DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-39 and Ndufa9

DIOPT Version :9

Sequence 1:	NP_001262116.1	Gene:	ND-39 / 40272	FlyBaseID:	FBgn0037001	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001094222.1	Gene:	Ndufa9 / 362440	RGDID:	1307307	Length:	377	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	158/368 - (42%)
Similarity:	221/368 - (60%)	Gaps:	41/368 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 AAMKRGTGGRSSFNGIVATVFGATGFVGRYVCNKLGKSGTQMILPYRGDDSDVIRLKVTGDLGQV 113
            |.:..|.|||||.:|:||||||||||:||||.|.||:.|:|:|:|||.|..|.:.|::.|||||:
  Rat    39 AVIPHGKGGRSSVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDIYDTMHLRLMGDLGQL 103

  Fly   114 LFHFYNLEDPASIRDAVKHSNVVINLVGRDFETKNFKFKDVHVNGAERIARIAREAGVERLIHLS 178
            :|..::..|..|||.||:||||||||:||::||:||.|:||.||....||:.::||||||.||:|
  Rat   104 IFLEWDARDKDSIRKAVQHSNVVINLIGREWETRNFDFEDVFVNIPRAIAQASKEAGVERFIHVS 168

  Fly   179 SLNVEANPKDLYVKGGSEWLKSKYEGELRVRDAFPNATIIRPADIYGSEDRFLRYYAHIWRRQFR 243
            .||..       :|..::.|:||..||..||..||:|.||||:|::|.|||||.::|:.  |.|.
  Rat   169 HLNAS-------MKSSAKSLRSKAVGEKEVRTVFPDAIIIRPSDMFGREDRFLNHFANY--RWFL 224

  Fly   244 SMPLWHKGEKTVKQPVYVSDVAQAIINAAKDPDSAGRIYQAVGPKRYQLSELVDWFHRLMRKDQK 308
            ::||...|.|||||||||:||::.|.||.|:||:.|:.:...||.||.|..||.:...:..:...
  Rat   225 AVPLVSLGFKTVKQPVYVADVSKGIANATKNPDAIGKTFAFTGPNRYLLFHLVKYIFGMTHRTFI 289

  Fly   309 RWGYMRYDMRWDPTFLLKAKLNSFICPGTPIG---GLHP-------ARIEREAVTDKVLTGVPTL 363
            .:...|:...|                   ||   ||.|       .::||..::|.:.|.:|.|
  Rat   290 PYPLPRFVYSW-------------------IGRLFGLSPFEPWTTKDKVERIHISDVMATDLPGL 335

  Fly   364 EDLGVTLTTMEQQVPWELRPYRAALYYDAELGEFETPSPPKCI 406
            |||||..|.:|.:....||.:|...:..:|:   |...|.|.:
  Rat   336 EDLGVQPTPLELKSIEVLRRHRTYRWLSSEI---EETKPAKTV 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-39	NP_001262116.1	NDUFA9_like_SDR_a	64..354	CDD:187579	132/299 (44%)
ND-39	NP_001262116.1	Epimerase	66..282	CDD:279681	115/215 (53%)
Ndufa9	NP_001094222.1	NDUFA9_like_SDR_a	54..326	CDD:187579	132/299 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354417
Domainoid	1	1.000	141	1.000	Domainoid score	I4614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3666
Inparanoid	1	1.050	267	1.000	Inparanoid score	I2960
OMA	1	1.010	-	-		QHG53586
OrthoDB	1	1.010	-	-		D465933at33208
OrthoFinder	1	1.000	-	-		FOG0004832
OrthoInspector	1	1.000	-	-		oto95928
orthoMCL	1	0.900	-	-		OOG6_101633
Panther	1	1.100	-	-	LDO	PTHR12126
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3413
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910