DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-39 and nduf-9

DIOPT Version :9

Sequence 1:	NP_001262116.1	Gene:	ND-39 / 40272	FlyBaseID:	FBgn0037001	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_497675.1	Gene:	nduf-9 / 175429	WormBaseID:	WBGene00021800	Length:	431	Species:	Caenorhabditis elegans

Alignment Length:	394	Identity:	161/394 - (40%)
Similarity:	227/394 - (57%)	Gaps:	18/394 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 VGVLCLRGYSAAAAPPEDG-PRPLKTTNPAAMKRGTGGRSSFNGIVATVFGATGFVGRYVCNKLG 84
            |.|:..:.:|:|....|:. |.|..::..|..::|.|||:||:|.|.|||||:||:|..|.||..
Worm    16 VSVVGSQNFSSAVTSAENAHPEPRVSSQSAQFRKGAGGRASFSGNVVTVFGASGFLGLPVVNKFA 80

  Fly    85 KSGTQMILPYRGDDSDVIRLKVTGDLGQVLFHFYNLEDPASIRDAVKHSNVVINLVGRDFETKNF 149
            |:|:|:|:|||.|...:...||.|:|||||:..:.|.|..|||.|||:|||||||:|....|..:
Worm    81 KNGSQIIIPYRQDPYYMREHKVLGELGQVLYFPFELMDEESIRKAVKYSNVVINLIGTRVPTGKY 145

  Fly   150 KFKDVHVNGAERIARIAREAGVERLIHLSSLNVEANPKDLYVKGGSEWLKSKYEGELRVRDAFPN 214
            .:.||:..||.|:|||.:|.|||:.:|||:|.....|:..:....|::|.||..||:.||:.||.
Worm   146 NYYDVNDTGARRLARICKEMGVEKFVHLSALGATTQPQKGHFVAKSQFLHSKGLGEVAVREEFPE 210

  Fly   215 ATIIRPADIYGSEDRFLRYYAHIWRR-QFRSMPLWHKGEKTVKQPVYVSDVAQAIINAAKDPDSA 278
            ||||||:.|||..|.|::||...||: ....:.|:.|||:|.|.|::|.|||..|.:|..||.:.
Worm   211 ATIIRPSVIYGELDGFIQYYVSRWRKTPLDYVYLYKKGEETYKMPIWVGDVAAGIQSAVNDPTAK 275

  Fly   279 GRIYQAVGPKRYQLSELVDWFHRLMR-KDQKRWGYMRYDMRWDPTFL-------LKAKLNSFICP 335
            |..|:.|||..||||||:|:.::... .....:.|.|:.|. ||.|:       |..|:  |.|.
Worm   276 GHTYEFVGPHCYQLSELIDFMYKKAHCLSDFGFRYKRHGMP-DPYFMALTMATELYGKV--FKCK 337

  Fly   336 GTPIGGLHPARIEREAVTDKVLTGVPTLEDLGVTLTTMEQQVPWELRPYRA-ALYYDAELGEFET 399
             .|   |:...:|...|...:|||..||.||||...|..:....:...||: ..|::.:.||...
Worm   338 -VP---LNREWMEFVEVQSDILTGERTLADLGVRRLTEFELAGGQQAFYRSFNRYFEEQYGELPA 398

  Fly   400 PSPP 403
            ||.|
Worm   399 PSLP 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-39	NP_001262116.1	NDUFA9_like_SDR_a	64..354	CDD:187579	128/298 (43%)
ND-39	NP_001262116.1	Epimerase	66..282	CDD:279681	102/216 (47%)
nduf-9	NP_497675.1	NDUFA9_like_SDR_a	61..352	CDD:187579	128/297 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167796
Domainoid	1	1.000	144	1.000	Domainoid score	I2855
eggNOG	1	0.900	-	-		E1_COG0702
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3666
Inparanoid	1	1.050	255	1.000	Inparanoid score	I1953
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D465933at33208
OrthoFinder	1	1.000	-	-		FOG0004832
OrthoInspector	1	1.000	-	-		oto18585
orthoMCL	1	0.900	-	-		OOG6_101633
Panther	1	1.100	-	-	LDO	PTHR12126
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4275
SonicParanoid	1	1.000	-	-		X3413
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.830