Protein Alignment ZnT77C and COT1

DIOPT Version :9

• Sequence 1: NP_649233.2
• Gene: ZnT77C / 40271
• FlyBaseID: FBgn0037000
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_014961.3
• Gene: COT1 / 854494
• SGDID: S000005843
• Length: 439
• Species: Saccharomyces cerevisiae
• Alignment Length: 478
• Identity: 110/478 - (23%)
• Similarity: 191/478 - (39%)
• Gaps: 124/478 - (25%)

  Fly    10 KPIPLYTVLVLSICYFVLQLILSHLTHGLTLLMASHHMLCNIFALGGCIITIKHSKQAPEARNPS 74
            |.:.:.::|:|...:|.:::...:|:|.|.|:..|.|||.:|.:|...:..:..:|.    |||.
Yeast     6 KQVKIISLLLLDTVFFGIEITTGYLSHSLALIADSFHMLNDIISLVVALWAVNVAKN----RNPD 66

  Fly    75 PALTKINGSGVAISLADTDAQTRAKRECREQKLRNTFGWARIDILTMLIVFIILASLSFSLVVEA 139
            ...                                |:||.|.:||..||..:.|.:|..|:::||
Yeast    67 STY--------------------------------TYGWKRAEILGALINAVFLIALCVSILIEA 99

  Fly   140 LQTLVHIDHQDTMHLPIPVMMLGFIGLILNGLTYLLI---------GGYTLHQGSF----LHL-- 189
            ||.::   ....:..|..|:.:|..|||.|.:...|.         |....|.|.|    :|:
Yeast   100 LQRII---APPVIENPKFVLYVGVAGLISNTVGLFLFHDNDQEHGHGHGHSHGGIFADHEMHMPS 161

  Fly   190 ---------------TPGG----------NVVLERPMSSNLDLSLTPMQRHLSKSRNDRQLREEL 229
                           ||..          |.:::..|:.|..| |||  .:.||:.:.......:
Yeast   162 SHTHTHAHVDGIENTTPMDSTDNISEIMPNAIVDSFMNENTRL-LTP--ENASKTPSYSTSSHTI 223

  Fly   230 ETEVGSVYFATKRQGAVEM-------LRDVSSTIFVIVCAAIVYVAEDEQHTAKFIDPVLSIFSC 287
            .:. |:.....||:.::.|       |.|....|.|::.|..::  :.:.....:.||::|:...
Yeast   224 ASG-GNYTEHNKRKRSLNMHGVFLHVLGDALGNIGVMLSAFFIW--KTDYSWKYYTDPLVSLIIT 285

  Fly   288 VLLVTLSYPYMKESCLILLQTIPGSIDLEIFERTLVTKFPEIISYHDLHIWQLAAHRYVATIHIQ 352
            .::.:.:.|...::..||||..|.::..:..|..|: |.|.||:.||.|||.|....::|::|||
Yeast   286 GIIFSSALPLSCKASKILLQATPSTLSGDQVEGDLL-KIPGIIAIHDFHIWNLTESIFIASLHIQ 349

  Fly   353 FQ-NPKLYLKIIEQVRSYFHDQGIGAVTIQPEFY--------------------------PSTNK 390
            .. :|:.:..:.:.|||..|..||.:.|:||||.                          |.|..
Yeast   350 LDISPEQFTDLAKIVRSKLHRYGIHSATLQPEFITREVTSTERAGDSQGDHLQNDPLSLRPKTYG 414

  Fly   391 NASASLECLM----QCQAVECIE 409
            ...:...||:    .|...:|:|
Yeast   415 TGISGSTCLIDDAANCNTADCLE 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT77C	NP_649233.2	CzcD	14..384	CDD:224151	100/417 (24%)
		Cation_efflux	25..306	CDD:279834	68/327 (21%)
COT1	NP_014961.3	CzcD	9..384	CDD:224151	102/420 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45820
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910