Protein Alignment ZnT77C and SLC30A6

DIOPT Version :9

• Sequence 1: NP_649233.2
• Gene: ZnT77C / 40271
• FlyBaseID: FBgn0037000
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001180442.1
• Gene: SLC30A6 / 55676
• HGNCID: 19305
• Length: 501
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 52/281 - (18%)
• Similarity: 107/281 - (38%)
• Gaps: 52/281 - (18%)

  Fly   110 TFGWARIDILTMLIVFIILASLSFSLVVEALQTLVHIDHQDTMHLPIPVMMLG-FIGLILNGLTY 173
            :||:.|:::|. :....:||.|....:::  ::......|..:|  ...:::| |:.|..|..|.
Human   133 SFGFERLEVLA-VFASTVLAQLGALFILK--ESAERFLEQPEIH--TGRLLVGTFVALCFNLFTM 192

  Fly   174 LLIGGYTLHQGSFLHLTPGGNVVLERPMSSNLDLSLTPMQRHLSKSRNDRQLREELETEVGSVYF 238
            |     ::....|.:::...:....:...::|..||..:...||                 |::.
Human   193 L-----SIRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLS-----------------SIFL 235

  Fly   239 ATKRQGAVEMLRDVSSTIFVIVCAAIV----YVAEDEQHTAKFIDPVLSIFSCVLLVTLSYPYMK 299
            .....   .:|.|::....:.:...::    |.|.|   ||..|...|..|..:      ||...
Human   236 PRMNP---FVLIDLAGAFALCITYMLIEINNYFAVD---TASAIAIALMTFGTM------YPMSV 288

  Fly   300 ESCLILLQTIP----GSIDLEIFERTLVTKFPEIISYHDLHIWQLAAHRYVATIHIQFQNPKLYL 360
            .|..:||||.|    |.:|..|.|   |:....::...:.|.|.|.......::|::.:......
Human   289 YSGKVLLQTTPPHVIGQLDKLIRE---VSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQ 350

  Fly   361 KIIEQVRSYFHDQGIGAVTIQ 381
            .::..|.:..:.. :..:|:|
Human   351 MVLAHVTNRLYTL-VSTLTVQ 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT77C	NP_649233.2	CzcD	14..384	CDD:224151	52/281 (19%)
		Cation_efflux	25..306	CDD:279834	35/200 (18%)
SLC30A6	NP_001180442.1	CzcD	<113..371	CDD:224151	52/281 (19%)
		Cation_efflux	113..295	CDD:279834	35/200 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810