Protein Alignment ZnT77C and slc30a1

DIOPT Version :9

• Sequence 1: NP_649233.2
• Gene: ZnT77C / 40271
• FlyBaseID: FBgn0037000
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001007940.1
• Gene: slc30a1 / 493316
• XenbaseID: XB-GENE-484357
• Length: 493
• Species: Xenopus tropicalis
• Alignment Length: 552
• Identity: 131/552 - (23%)
• Similarity: 219/552 - (39%)
• Gaps: 176/552 - (31%)

  Fly    12 IPLYTVLVLSICYFVLQLILSHLTHGLTLLMASHHMLCNIFALGGCIITIKHSKQAPEARNPSPA 76
            :.|..:|.|:..:||:::::|.:|..|.:|..|.|||.::.||...::.::.:::.
 Frog     7 VRLLFMLALTFIFFVVEVVVSRVTGSLAMLSDSFHMLSDVIALVVGLVAVRFAQKT--------- 62

  Fly    77 LTKINGSGVAISLADTDAQTRAKRECREQKLRNTFGWARIDILTMLIVFIILASLSFSLVVEALQ 141
                         ..||              :|||||.|..::..|:..:.|.:|.|::|:||::
 Frog    63 -------------RSTD--------------KNTFGWIRAGVMGALVNAVFLTALCFTIVLEAIE 100

  Fly   142 TLVHIDHQDTMHLPIPVMMLGFIGLILNGLTYLLIG--------GYTLHQGSFLHLTPGGNVVLE 198
               .......:..|:.||.:|..||::|     |||        |:....|...|
 Frog   101 ---RFTEPQAIEQPLVVMGVGAGGLLIN-----LIGLCMFRDSAGHGHSHGGHGH---------- 147

  Fly   199 RPMSSNLDLSLTPMQRHLSKSRN-DRQLREELETEVGSVYFATKRQGA----------------- 245
               |.....|..|.:|...:|.. ||:....|....|:...|...:|.
 Frog   148 ---SHGAKKSHRPRERAAGESAALDREETNILVENCGNSLAAAAAEGMPGKHDALAENIVDGRVN 209

  Fly   246 ------------------------VEMLRDVSSTIFVIVCAAIVYVAED-------------EQH 273
                                    :.:|.|...::.|::.|.:.|...:             |.|
 Frog   210 GNVIENNLPEIHEDGTQLNMRGVFLHVLGDALGSVIVVLNALVFYFVFNPCPSDEGCINPCVEDH 274

  Fly   274 TAK-----------------------------FIDPVLS-IFSCVLLVTLSYPYMKESCLILLQT 308
            ..|                             ::||.|. |..|:||.| :||.:|||.||||||
 Frog   275 CDKKVNVSALSSNPDNTSSPPEIQMAGPCWVLYLDPSLCVIMVCILLYT-TYPLLKESALILLQT 338

  Fly   309 IPGSIDLEIFERTLVTKFPEIISYHDLHIWQLAAHRYVATIHIQFQNPKLYLKIIEQVRSYFHDQ 373
            :|..||:...::.| .....:.:.|:||:||||..|.:||.||:..:|..|:.:.::::.:|||:
 Frog   339 VPKQIDISSLKQKL-KNLDGVEAVHELHVWQLAESRIIATAHIKCHDPTAYMDVAKRIKDFFHDE 402

  Fly   374 GIGAVTIQPEFYPSTNKNASASLECLMQCQAVECIEKVCCRDSRTDLREVCDAPSGRKSS----- 433
            ||.|.|||||| .|....:..|| |.:.|: .:|..|.||..:..::       ||:||:
 Frog   403 GIHATTIQPEF-SSVESGSRISL-CELSCR-TQCAPKQCCGSTEKNV-------SGKKSNCGAAS 457

  Fly   434 -SPVKCAGNSHEHSRAKSKSCAELSAVVVEKP 464
             |.:.....|.||:..::.:.        |||
 Frog   458 FSSLGMISESPEHATKRTNAS--------EKP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT77C	NP_649233.2	CzcD	14..384	CDD:224151	109/462 (24%)
		Cation_efflux	25..306	CDD:279834	74/373 (20%)
slc30a1	NP_001007940.1	CzcD	8..415	CDD:224151	111/466 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7998
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D458019at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45820
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020