Protein Alignment ZnT77C and slc30a5

DIOPT Version :9

• Sequence 1: NP_649233.2
• Gene: ZnT77C / 40271
• FlyBaseID: FBgn0037000
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001002322.1
• Gene: slc30a5 / 436594
• ZFINID: ZDB-GENE-040718-6
• Length: 775
• Species: Danio rerio
• Alignment Length: 447
• Identity: 94/447 - (21%)
• Similarity: 167/447 - (37%)
• Gaps: 122/447 - (27%)

  Fly     2 VKDILQRCKPIPLYTVLVLSICYFVLQLILSHLTHGLTLLMASHHML--CNIFALGGCIITIKHS 64
            :|.||:......::..|.|::.:..::|.....|:.|.|:....|||  |:...|
Zfish   403 LKQILEEYDSRQIFYFLCLNLAFTFVELFYGVWTNSLGLISDGFHMLFDCSALVL---------- 457

  Fly    65 KQAPEARNPSPALTKINGSGVAISLADTDAQTRAKRECREQKLRNTFGWARIDILTMLIVFIILA 129
                               |:..:|......||.          .::|:.|::||:..|..:.|.
Zfish   458 -------------------GLFAALMTRWKATRI----------YSYGYGRVEILSGFINGLFLM 493

  Fly   130 SLSFSLVVEALQTLVHIDHQDT-MHLPIPVMMLGFIGLILNGLTYLLIG---------------- 177
            .::|.:.||::..||...:.:| |..|:.|.     |||:|     |:|
Zfish   494 VIAFFVFVESVTRLVDPPNINTDMLTPVSVG-----GLIVN-----LVGICAFSHAHSHGASKGS 548

  Fly   178 ------GYTLH----------QGSFLHLTPGGNVVLERPMSSNLDLSLTPMQRHLSKSRNDRQLR 226
                  |::.|          .|...| :.||:           ..|......|.|...|
Zfish   549 CSGHDHGHSHHGHGHSSMEHSHGGHGH-SHGGH-----------GHSHGHGHSHSSGGMN----- 596

  Fly   227 EELETEVGSVYFATKRQGAVEMLRDVSSTIFVIVCAAIVYVAEDEQHTAKFIDPVLSIFSCVLLV 291
                        |..|...:.:|.|...::.||:...::     .|......||:.|:|...|:.
Zfish   597 ------------ANMRGVFLHVLADTLGSVGVIISTILI-----RQFGWLIADPICSLFISTLIF 644

  Fly   292 TLSYPYMKESCLILLQTIPGSIDLEI-FERTLVTKFPEIISYHDLHIWQLAAHRYVATIHIQFQN 355
            ....|.:|::|.:||..:|...:.|: |....:.|...::||.|.|.|:.:|.....|||:|..:
Zfish   645 LSVIPLLKDACEVLLLRMPPQHEKELNFALEKIQKIEGVLSYRDPHFWRHSASVIAGTIHLQLMS 709

  Fly   356 PKLYLKIIEQVRSYFHDQGIGAVTIQPE---FYPSTNKNASASLECLMQCQAVECIE 409
            ..:..::|:||.:...|.|:..:|||.|   ::...:..:|...|.|...|.:|.::
Zfish   710 DVVEQRVIQQVSAVLKDAGVNNLTIQLEKEAYFQHMSGLSSGFHEVLTMTQQMESMK 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT77C	NP_649233.2	CzcD	14..384	CDD:224151	86/408 (21%)
		Cation_efflux	25..306	CDD:279834	59/315 (19%)
slc30a5	NP_001002322.1	CzcD	411..739	CDD:224151	86/410 (21%)
		Cation_efflux	424..659	CDD:279834	59/317 (19%)
		His-rich loop	538..584		6/57 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..592		8/56 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810