Protein Alignment ZnT77C and ZnT63C

DIOPT Version :9

• Sequence 1: NP_649233.2
• Gene: ZnT77C / 40271
• FlyBaseID: FBgn0037000
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 130/509 - (25%)
• Similarity: 238/509 - (46%)
• Gaps: 128/509 - (25%)

  Fly     1 MVKDILQRCKPIPLYTVLVLSICYFVLQLILSHLTHGLTLLMASHHMLCNIFALGGCIITIKHSK 65
            |.|...::|:   |.:::.|:..:|.:::|:.::|:.:.|:..|.|||.:|.||   :|:....|
  Fly     1 MAKYSGKKCR---LLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAAL---VISFLSVK 59

  Fly    66 QAPEARNPSPALTKINGSGVAISLADTDAQTRAKRECREQKLRNTFGWARIDILTMLIVFIILAS 130
            .:|:..:                                   :|||||||.::|..|:..:.|.:
  Fly    60 MSPKKWS-----------------------------------KNTFGWARAEVLGALVNAVFLVA 89

  Fly   131 LSFSLVVEALQTLVHIDHQDTMHLPIPVMMLGFIGLILNGLTYLLIGGYTLHQGSFLHLTPGGNV 195
            |.||:.:||.:..:   .::.:|.|..::::|.:||::|.:...|:..:..|.|   |...||
  Fly    90 LCFSITIEACKRFI---EEEPIHEPELLVIVGALGLLVNVIGLCLLYEHGGHHG---HSHGGG-- 146

  Fly   196 VLERPMSSNLDLSLTPMQRHLSKSRNDRQLREELETEVGSVYFATKRQ----------------- 243
                         ||.....|::..|    .:|.|.|...  ||.::|
  Fly   147 -------------LTRNHSRLTELAN----MDEGEDEQND--FAYEKQKEKAPVKKSSHGHSHDP 192

  Fly   244 ------GA-VEMLRDVSSTIFVIVCAAIVYVAEDEQHTAKFIDPVLSIFSCVLLVTLSYPYMKES 301
                  || :.:|.|...:|.|::.|.:|:  :.|.....::||.|||...||::...:|.::||
  Fly   193 GQMNMRGAFLHVLSDALGSIIVVISAVVVW--KTEWKYRYYMDPALSIVLVVLILHSVWPLLRES 255

  Fly   302 CLILLQTIPGSIDLEIFERTLVTKFPEIISYHDLHIWQLAAHRYVATIHIQFQNPKLYLKIIEQV 366
            .||||||:|..|.::..::.|:.|...:::.|:.|:||||..|.:|:.||:.:|...|:||.|:|
  Fly   256 ALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKV 320

  Fly   367 RSYFHDQGIGAVTIQPEFYP---------STNKNASASLECLMQCQAVE--CIEKVCCRDSRTDL 420
            :.:||::||.:.||||||..         :::.|.|.|..|.:.|...|  |::..||:::
  Fly   321 KEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDCCALDCPTTEEGCVKATCCQNN---- 381

  Fly   421 REVCDAPSGRKSSSPVKCAGNSHEHSRAKSKSCAELSAVVVEKPEELSAGQLLK 474
            .::...||  .::||..|          :.::.|..:.       ::.||.||:
  Fly   382 NKLNQLPS--PTNSPYLC----------RQRNAARQAG-------DVEAGSLLE 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT77C	NP_649233.2	CzcD	14..384	CDD:224151	106/393 (27%)
		Cation_efflux	25..306	CDD:279834	72/304 (24%)
ZnT63C	NP_001261364.1	CzcD	10..339	CDD:224151	107/398 (27%)
		Cation_efflux	21..260	CDD:279834	72/305 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457009
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D458019at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51382
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45820
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850