Protein Alignment ZnT77C and Slc30a4

DIOPT Version :9

• Sequence 1: NP_649233.2
• Gene: ZnT77C / 40271
• FlyBaseID: FBgn0037000
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_035904.2
• Gene: Slc30a4 / 22785
• MGIID: 1345282
• Length: 430
• Species: Mus musculus
• Alignment Length: 354
• Identity: 69/354 - (19%)
• Similarity: 156/354 - (44%)
• Gaps: 81/354 - (22%)

  Fly     3 KDILQRCKPIPLYTV-LVLSICYFVLQLILSHLTHGLTLLMASHHMLCNIFALGGCIITIKHSKQ 66
            :::|::.|.....|: .||.:.:.:.:|:..::.:.|.::..:.|||.::.|:...::.:..|.:
Mouse   102 RELLKQRKVKTRLTIAAVLYLLFMIGELVGGYMANSLAIMTDALHMLTDLSAIILTLLALWLSSK 166

  Fly    67 APEARNPSPALTKINGSGVAISLADTDAQTRAKRECREQKLRNTFGWARIDILTMLIVFIILASL 131
            :|                           ||          |.|||:.|:::|:.:|..:::..|
Mouse   167 SP---------------------------TR----------RFTFGFHRLEVLSAMISVMLVYVL 194

  Fly   132 SFSLVVEALQTLVHIDHQ---DTMHLPIPVMMLGFIGLILNGLTYLLIGGYTLHQGSFLHLTPGG 193
            ...|:.||:|..:|::::   |.|      ::...:|:.:|     :|.|:.|:|....|
Mouse   195 MGFLLYEAVQRTIHMNYEINGDVM------LITAAVGVAVN-----VIMGFLLNQSGHHH----- 243

  Fly   194 NVVLERPMSSNLDLSLTPMQRHLSKSRNDRQLREELETEVGSVYFATKRQGAVEMLRDVSSTIFV 258
                ....|.:|..:...|   :|...|..|  :.|..          |...|..|.|:..::.|
Mouse   244 ----SHAHSHSLPSNSPSM---VSSGHNHGQ--DSLAV----------RAAFVHALGDLVQSVGV 289

  Fly   259 IVCAAIVYVAEDEQHTAKFIDPVLSIFSCVLLVTLSYPYMKESCLILLQTIPGSIDLEIFERTLV 323
            ::.|.|:....:    .|..||:.:....:|:...::..:.::.:|:|:.:|..::::..:.:|:
Mouse   290 LIAAYIIRFKPE----YKIADPICTYIFSLLVAFTTFRIIWDTVVIILEGVPSHLNVDYIKESLM 350

  Fly   324 TKFPEIISYHDLHIWQLAAHRYVATIHIQ 352
             |..::.|..||:||.|.:.:..|.:|:|
Mouse   351 -KIEDVYSVEDLNIWSLTSGKSTAIVHMQ 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT77C	NP_649233.2	CzcD	14..384	CDD:224151	67/343 (20%)
		Cation_efflux	25..306	CDD:279834	51/283 (18%)
Slc30a4	NP_035904.2	CDF	123..414	CDD:273544	64/333 (19%)
		Cation_efflux	123..333	CDD:279834	51/285 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..264		4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D820567at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820