Protein Alignment isoQC and H27A22.1

DIOPT Version :9

• Sequence 1: NP_788550.1
• Gene: isoQC / 40270
• FlyBaseID: FBgn0036999
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001041144.1
• Gene: H27A22.1 / 179482
• WormBaseID: WBGene00010418
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 310
• Identity: 127/310 - (40%)
• Similarity: 182/310 - (58%)
• Gaps: 34/310 - (10%)

  Fly    57 NLSDKLHLREAIDKILIPRVVGTTNHSIVREYIVQSLRDLDWDVEVNSFHDHAPIKGKLHFHNII 121
            :.::....:|.:..|::||:|.|..|..|.:|:...|.:|.:..|.::|.|..|: |..:|.|:|
 Worm    57 DFTNTTRFKEILAPIMVPRIVDTKQHRQVGDYLQSFLHNLGFATEWDAFTDTTPL-GTRNFRNLI 120

  Fly   122 ATLNPNAERYLVLSCHYDSKYMPGVEFLGATDSAVPCAMLLNLAQVLQEQLKPLKKSKLSLMLLF 186
            ||.:.:|.|.|||:||||||.:||...:.||||||||||:|::||.|...:......::.|.|:|
 Worm   121 ATFDESAPRRLVLACHYDSKIIPGQVMIAATDSAVPCAMMLDIAQTLAPYMYKRVAQQIGLQLIF 185

  Fly   187 FDGEEAFEEWGPKDSIYGARHLAKKWHHE--------------GKLDRIDMLVLLDLLGAPDPAF 237
            |||||||.:|...||:||:||||:||..:              .:|||||:|:|||||||.:|:
 Worm   186 FDGEEAFRDWTATDSLYGSRHLAQKWEQKWYPSSSSLNNFELSKELDRIDVLMLLDLLGAANPS- 249

  Fly   238 YSFFENT-----ESWYMRIQSVETRLAKLQLLERYASSGVAQRDPTRYFQSQAMRSSFIEDDHIP 297
               ..||     ...:.::..||:.|         .:||.........|..| :..:.:||||||
 Worm   250 ---IGNTIGMGANDLFSQLADVESNL---------RTSGCLSSLRRNVFNKQ-LSYNQVEDDHIP 301

  Fly   298 FLRRNVPILHLIPVPFPSVWHTPDDNASVIDYATTDNLALIIRLFALEYL 347
            ||:|.|||||||.||||||||...|||:.:.|.|.|::..:||:|..:||
 Worm   302 FLKRGVPILHLITVPFPSVWHRSSDNANALHYPTIDHMTAVIRVFVAKYL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
isoQC	NP_788550.1	M28_QC_like	56..346	CDD:193501	125/307 (41%)
H27A22.1	NP_001041144.1	M28_QC_like	50..350	CDD:349876	125/307 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55920
OrthoDB	1	1.010	-	-		D1257754at2759
OrthoFinder	1	1.000	-	-		FOG0001509
OrthoInspector	1	1.000	-	-		otm14729
orthoMCL	1	0.900	-	-		OOG6_102560
Panther	1	1.100	-	-	LDO	PTHR12283
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2349
SonicParanoid	1	1.000	-	-		X1074
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.960