DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5955 and HSD3B7

DIOPT Version :9

Sequence 1:	NP_649230.1	Gene:	CG5955 / 40268	FlyBaseID:	FBgn0036997	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_079469.2	Gene:	HSD3B7 / 80270	HGNCID:	18324	Length:	369	Species:	Homo sapiens

Alignment Length:	161	Identity:	44/161 - (27%)
Similarity:	65/161 - (40%)	Gaps:	22/161 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LITGGLGQLGIECAKLL---RTQYGSQNVILSDIIKPSQSVLENGPY----IFADILDFKGLQKI 106
            |:|||.|.||....::|   ..:.|...| ....:.|....|:.||.    |..|:.....:...
Human    13 LVTGGCGFLGEHVVRMLLQREPRLGELRV-FDQHLGPWLEELKTGPVRVTAIQGDVTQAHEVAAA 76

  Fly   107 VVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFV-PSTIGAFGPDSPR 170
            |....:  :||.:.|:...|..:......||::|..||||...|...|..| .|::...||::..
Human    77 VAGAHV--VIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVVGPNTKG 139

  Fly   171 NP-------TPNVTIQR-PRTIYGVSKVHAE 193
            :|       ||...:.| |   |..||..||
Human   140 HPFYRGNEDTPYEAVHRHP---YPCSKALAE 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5955	NP_649230.1	WcaG	47..355	CDD:223528	44/161 (27%)
CG5955	NP_649230.1	TDH_SDR_e	47..351	CDD:187580	44/161 (27%)
HSD3B7	NP_079469.2	3b-HSD_HSDB1_like_SDR_e	11..361	CDD:187671	44/161 (27%)
HSD3B7	NP_079469.2	3Beta_HSD	13..291	CDD:279420	44/161 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810