Protein Alignment Tdh and Sdr42e1

DIOPT Version :10

• Sequence 1: NP_649230.1
• Gene: Tdh / 40268
• FlyBaseID: FBgn0036997
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_083001.1
• Gene: Sdr42e1 / 74032
• MGIID: 1921282
• Length: 394
• Species: Mus musculus
• Alignment Length: 313
• Identity: 77/313 - (24%)
• Similarity: 114/313 - (36%)
• Gaps: 83/313 - (26%)

  Fly    40 PRESRPPKILITGGLGQLG--IECAKLLRTQYGSQNVILSDIIKPSQSVLENGPYIFADILDFKG 102
            |.|:    :|||||.|..|  :.||   ..|.|:: |||.||.:|:|::.|...::..||.....
Mouse     7 PEET----VLITGGGGYFGFRLGCA---LNQKGAR-VILFDITQPAQNLPEGIKFVCGDIRCLAD 63

  Fly   103 LQKIVVD-HRIDWLIHFSAL-LSAVGEQNVPLAVRVNIEGVHNVIELAKQYKL-RIFVPSTIGA- 163
            ::....| .::..:.|.::. :|...:.|......||:.|..|::....:..: |:...||...
Mouse    64 VETAFQDAEKVACVFHVASYGMSGREQLNKTQIEEVNVGGTENILRACLERGVPRLVYTSTFNVI 128

  Fly   164 FGPDSPRN---PTPNVTIQRPRTIYGVSKVHAELIGEYYYHKFGLDFRCLRFPGVISSDPPGGGT 225
            ||....||   ..|.:.:......|..:|..||   :......||.|:            .|.|
Mouse   129 FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAE---KKVLEANGLAFK------------QGDG- 177

  Fly   226 TDYAVAVFHEALRNGKYTCYLRP--------DTRLP--MMYIEDCLRALLEFMRAPNEQLKRRVY 280
                      .||    ||.:||        ...||  :.|||   |.|..|:....:.|...|
Mouse   178 ----------ILR----TCAIRPAGIYGAGEQRHLPRIVSYIE---RGLFRFVYGDPQSLVEFV- 224

  Fly   281 NVTAMSFTPEELFAQLGKHVPNLHVTYKPDSRQLIAD----AWPQVFDDSDAR 329
                              ||.||...:...|..|.||    |..|.:..||.|
Mouse   225 ------------------HVDNLAKAHILASEALKADKGHVASGQPYFISDGR 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdh	NP_649230.1	TDH_SDR_e	47..351	CDD:187580	75/306 (25%)
Sdr42e1	NP_083001.1	Rossmann-fold NAD(P)(+)-binding proteins	10..351	CDD:473865	75/310 (24%)