Protein Alignment CG5955 and GFUS

DIOPT Version :9

• Sequence 1: NP_649230.1
• Gene: CG5955 / 40268
• FlyBaseID: FBgn0036997
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_001304712.1
• Gene: GFUS / 7264
• HGNCID: 12390
• Length: 327
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 75/352 - (21%)
• Similarity: 118/352 - (33%)
• Gaps: 107/352 - (30%)

  Fly    47 KILITGGLGQLGIECAKLLRTQYGSQNVILSDIIKPSQSVLENG------PYIF-----ADILDF 100
            :||:|||.|.:|                      |..|.|:.:|      .::|     ||:.|.
Human    15 RILVTGGSGLVG----------------------KAIQKVVADGAGLPGEDWVFVSSKDADLTDT 57

  Fly   101 KG----LQKIVVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIE----GVH---NVIELAKQYKLR 154
            ..    .:|:...|    :||.:|::..:...     ::.|::    .||   ||:..|.:...|
Human    58 AQTRALFEKVQPTH----VIHLAAMVGGLFRN-----IKYNLDFWRKNVHMNDNVLHSAFEVGAR 113

  Fly   155 IFVPSTIGAFGPDSPRNPTPNVTIQR--PRTI---YGVSKVHAELIGEYYYHKFGLDFRCLRFPG 214
            ..|........||....|.....|..  |...   |..:|...::....|:.::|    | .|..
Human   114 KVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYG----C-TFTA 173

  Fly   215 VISSDPPG---------GGTTDYAVAVFHEALRNGK-YTCYLRPDTRLPMMYIEDCLRALLEFMR 269
            ||.::..|         |......:...|.|..:|. .|.:...:.|...:|..|..:..:..:|
Human   174 VIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLR 238

  Fly   270 APNE--------------QLKRRVYNVT-AMSFTPEELF------AQLGKHVPNLHV-TYKPDSR 312
            ..||              .:|.....|. ||.|..|..|      .|..|...|..: ||.||.|
Human   239 EYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFR 303

  Fly   313 -----QLIAD--AWPQVFDDS--DARR 330
                 |.:.:  ||   |.|:  .||:
Human   304 FTPFKQAVKETCAW---FTDNYEQARK 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5955	NP_649230.1	WcaG	47..355	CDD:223528	75/352 (21%)
		TDH_SDR_e	47..351	CDD:187580	75/352 (21%)
GFUS	NP_001304712.1	GDP_FS_SDR_e	15..318	CDD:187550	71/341 (21%)
		Epimerase	16..251	CDD:279681	53/270 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810