Protein Alignment Tdh and tdh2

DIOPT Version :10

• Sequence 1: NP_649230.1
• Gene: Tdh / 40268
• FlyBaseID: FBgn0036997
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_001092887.1
• Gene: tdh2 / 556781
• ZFINID: ZDB-GENE-070620-14
• Length: 363
• Species: Danio rerio
• Alignment Length: 367
• Identity: 202/367 - (55%)
• Similarity: 264/367 - (71%)
• Gaps: 27/367 - (7%)

  Fly     3 RKCLASLALAPVASPIPL-PRITPIASQLVQRRAFHQVPR-----ESRP----PKILITGGLGQL 57
            |.|:.||....:|..:.| ||               ||.|     .|.|    |::|||||||||
Zfish     6 RLCVRSLCNGRMARGMSLSPR---------------QVNRWPSSESSEPPTDSPRVLITGGLGQL 55

  Fly    58 GIECAKLLRTQYGSQNVILSDIIKPSQSVLENGPYIFADILDFKGLQKIVVDHRIDWLIHFSALL 122
            |:..|::||.|||.:|:|||||.:|...|...||:::||:||:|.|:::||::||.||:|:||||
Zfish    56 GVGLAQMLRQQYGKENIILSDIRRPPTEVYNMGPFVYADVLDYKNLRELVVNNRITWLVHYSALL 120

  Fly   123 SAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFVPSTIGAFGPDSPRNPTPNVTIQRPRTIYGV 187
            ||:||.||.||..:||.|:|||::||.:..||:|||||||||||.|||:|.|::.||||||||||
Zfish   121 SAIGEANVALARTINITGLHNVLDLALENCLRLFVPSTIGAFGPSSPRDPAPDLCIQRPRTIYGV 185

  Fly   188 SKVHAELIGEYYYHKFGLDFRCLRFPGVISS-DPPGGGTTDYAVAVFHEALRNGKYTCYLRPDTR 251
            |||||||:|||.:||:||||||||:|||:|: ..||||||||||.:||:||..|.:.|||||:||
Zfish   186 SKVHAELMGEYLHHKYGLDFRCLRYPGVVSAHTKPGGGTTDYAVQIFHDALSTGHHECYLRPNTR 250

  Fly   252 LPMMYIEDCLRALLEFMRAPNEQLKRRVYNVTAMSFTPEELFAQLGKHVPNLHVTYKPDS-RQLI 315
            ||||:|.||.||.:|||:||...|..|.||:.||||||.|:..::.|.:|:|.|||.||: ||.|
Zfish   251 LPMMHISDCHRATIEFMQAPESCLSLRTYNIAAMSFTPGEVAEEIRKLLPHLRVTYNPDAIRQKI 315

  Fly   316 ADAWPQVFDDSDARRDWHWQHKYDLSNLVDFMIKDVQDNYIN 357
            ||:||..||||:||:||.|:..:.||.||..|:..:::...|
Zfish   316 ADSWPVRFDDSNARQDWGWKPAFSLSELVTDMLASIREKRTN 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdh	NP_649230.1	TDH_SDR_e	47..351	CDD:187580	187/305 (61%)
tdh2	NP_001092887.1	TDH_SDR_e	45..351	CDD:187580	187/305 (61%)