Protein Alignment CG5955 and HSD3B1

DIOPT Version :9

• Sequence 1: NP_649230.1
• Gene: CG5955 / 40268
• FlyBaseID: FBgn0036997
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_000853.1
• Gene: HSD3B1 / 3283
• HGNCID: 5217
• Length: 373
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 68/335 - (20%)
• Similarity: 130/335 - (38%)
• Gaps: 72/335 - (21%)

  Fly    49 LITGGLGQLGIECAKLLRTQYGSQNVILSD-----IIKPSQSVLENG---PYIFADILDFKGLQK 105
            |:||..|.||....:||..:...:.:.:.|     .::...|.|:|.   ..:..||||...|::
Human     7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDEPFLKR 71

  Fly   106 IVVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFV-PSTIGAFGPDSP 169
            ...|  :..:||.:.::...|..:....:.||::|...::|...|..:.:|: .|:|...||:|.
Human    72 ACQD--VSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSY 134

  Fly   170 RNPTPNVTIQRP-RTIYGVSKVHAELIGE--------YYYHKFGLDFRCLRFPGVISSDPPGGGT 225
            :....|...:.| ...:.....|::.:.|        :.....|..:.|...|..|.     |..
Human   135 KEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTCALRPMYIY-----GEG 194

  Fly   226 TDYAVAVFHEALRN-------GKYTCYLRPDTRLPMMYIED-------CLRALLEFMRAPNEQLK 276
            :.:..|..:|||.|       ||::. :.|      :|:.:       .||||.:..:||:  ::
Human   195 SRFLSASINEALNNNGILSSVGKFST-VNP------VYVGNVAWAHILALRALQDPKKAPS--IR 250

  Fly   277 RRVYNVTAMSFTPEELFAQLGKHVPNLHVTYKPDSRQLIADAWPQVFDDSDARRDWHWQHKYDLS 341
            .:.|.::  ..||.:.:       .||:.|               :..:...|.|..|.....|.
Human   251 GQFYYIS--DDTPHQSY-------DNLNYT---------------LSKEFGLRLDSRWSFPLSLM 291

  Fly   342 NLVDFMIKDV 351
            ..:.|:::.|
Human   292 YWIGFLLEIV 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5955	NP_649230.1	WcaG	47..355	CDD:223528	68/335 (20%)
		TDH_SDR_e	47..351	CDD:187580	67/333 (20%)
HSD3B1	NP_000853.1	3b-HSD_HSDB1_like_SDR_e	5..357	CDD:187671	68/335 (20%)
		3Beta_HSD	7..287	CDD:279420	65/319 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810