Protein Alignment Tdh and Hsd3b2

DIOPT Version :10

• Sequence 1: NP_649230.1
• Gene: Tdh / 40268
• FlyBaseID: FBgn0036997
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_058961.4
• Gene: Hsd3b2 / 29632
• RGDID: 67377
• Length: 373
• Species: Rattus norvegicus
• Alignment Length: 226
• Identity: 58/226 - (25%)
• Similarity: 86/226 - (38%)
• Gaps: 59/226 - (26%)

  Fly    49 LITGGLGQLGIECAKLLRTQYGSQNV-ILSDIIKPSQ-------------SVLENGPYIFADILD 99
            |:||..|.||....:||..:...:.| :|..:.:|..             :|||      .||||
  Rat     7 LVTGAGGFLGQRIVQLLVQEKDLKEVRVLDKVFRPETREEFFNLGTSIKVTVLE------GDILD 65

  Fly   100 FKGLQKIVVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFV-PSTIGA 163
            .:.|::..  ..|..:||.:||:...|.......:.||::|..|::|...|..:..|: .||:..
  Rat    66 TQCLRRAC--QGISVVIHTAALIDVTGVNPRQTILDVNLKGTQNLLEACVQASVPAFIYCSTVDV 128

  Fly   164 FGPDSPRNPTPNVTIQRPRTIYGVSKVHAELI--GEYYYHKFGLDFRCLRFPGVISSDPPGGGTT 226
            .||:|.:....|          |..:.|.|..  ..|.|.|...:...|...|.|..:   |||.
  Rat   129 AGPNSYKKIILN----------GHEEEHHESTWSNPYPYSKKMAEKAVLAANGSILKN---GGTL 180

  Fly   227 DYAVAVFHEALRNGKYTCYLRPDTRLPMMYI 257
                           :||.|||      |||
  Rat   181 ---------------HTCALRP------MYI 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdh	NP_649230.1	TDH_SDR_e	47..351	CDD:187580	58/226 (26%)
Hsd3b2	NP_058961.4	Rossmann-fold NAD(P)(+)-binding proteins	5..357	CDD:473865	58/226 (26%)