DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5955 and Tdh

DIOPT Version :9

Sequence 1:	NP_649230.1	Gene:	CG5955 / 40268	FlyBaseID:	FBgn0036997	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001099514.1	Gene:	Tdh / 290315	RGDID:	1310214	Length:	373	Species:	Rattus norvegicus

Alignment Length:	324	Identity:	199/324 - (61%)
Similarity:	248/324 - (76%)	Gaps:	12/324 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 HQVP----------RESRPPKILITGGLGQLGIECAKLLRTQYGSQNVILSDIIKPSQSVLENGP 91
            |:||          .|:.||::||||||||||:..|.|||.::|..|||||||.||...|..:||
  Rat    37 HRVPANVNFHSTSFSEAEPPRVLITGGLGQLGVGLANLLRKRFGKDNVILSDIRKPPAHVFHSGP 101

  Fly    92 YIFADILDFKGLQKIVVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIF 156
            :|:|:|||:|.|::|||:|||.||.|:|||||||||.|||||..|||.|:||::::|.:|.:|:|
  Rat   102 FIYANILDYKNLREIVVNHRISWLFHYSALLSAVGEANVPLARDVNITGLHNILDVAAEYNVRLF 166

  Fly   157 VPSTIGAFGPDSPRNPTPNVTIQRPRTIYGVSKVHAELIGEYYYHKFGLDFRCLRFPGVISSD-P 220
            ||||||||||.|||||||::.:|||||||||||||.||:|||||:::||||||||:||:||:| .
  Rat   167 VPSTIGAFGPTSPRNPTPDLCVQRPRTIYGVSKVHTELMGEYYYYRYGLDFRCLRYPGIISADSQ 231

  Fly   221 PGGGTTDYAVAVFHEALRNGKYTCYLRPDTRLPMMYIEDCLRALLEFMRAPNEQLKRRVYNVTAM 285
            ||||||||||.:||.|.:||.:.|.|:..||||||||.|||||.||.|.||.|.|..|.||:.||
  Rat   232 PGGGTTDYAVQIFHAAAKNGTFECNLKASTRLPMMYISDCLRATLEVMEAPAECLSMRTYNINAM 296

  Fly   286 SFTPEELFAQLGKHVPNLHVTYKPDS-RQLIADAWPQVFDDSDARRDWHWQHKYDLSNLVDFMI 348
            |||||||...|.||.|:..:||..|. ||.||::||.:.|||:||:||.|:|.:||..||..|:
  Rat   297 SFTPEELALALRKHAPDFQITYCVDPLRQAIAESWPMILDDSNARKDWGWKHDFDLPELVATML 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5955	NP_649230.1	WcaG	47..355	CDD:223528	193/304 (63%)
CG5955	NP_649230.1	TDH_SDR_e	47..351	CDD:187580	193/304 (63%)
Tdh	NP_001099514.1	TDH_SDR_e	57..363	CDD:187580	193/304 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339851
Domainoid	1	1.000	336	1.000	Domainoid score	I1085
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10987
Inparanoid	1	1.050	418	1.000	Inparanoid score	I1751
OMA	1	1.010	-	-		QHG60810
OrthoDB	1	1.010	-	-		D1327602at2759
OrthoFinder	1	1.000	-	-		FOG0005649
OrthoInspector	1	1.000	-	-		oto97451
orthoMCL	1	0.900	-	-		OOG6_104776
Panther	1	1.100	-	-	LDO	PTHR42687
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4627
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770