Protein Alignment Tdh and Hsd3b7

DIOPT Version :10

• Sequence 1: NP_649230.1
• Gene: Tdh / 40268
• FlyBaseID: FBgn0036997
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_001385604.1
• Gene: Hsd3b7 / 246211
• RGDID: 628727
• Length: 369
• Species: Rattus norvegicus
• Alignment Length: 374
• Identity: 82/374 - (21%)
• Similarity: 127/374 - (33%)
• Gaps: 114/374 - (30%)

  Fly    49 LITGGLGQLGIECAK-LLRTQYGSQNVILSDI-IKPSQSVLENGPY----IFADILDFKGLQKIV 107
            |:|||.|.||....: ||..:...:.:.:.|: :......|:.||.    |..|:.....:...:
  Rat    13 LVTGGCGFLGEHIVRMLLEWEPRLRELRVFDLHLSSWLEELKTGPVQVTAIQGDVTQAHEVAAAM 77

  Fly   108 VDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFV-PSTIGAFGP----- 166
            ....:  :||.:.|:...|:.:.....:||::|..|||:...|...|:.| .|::...||
  Rat    78 AGSHV--VIHTAGLVDVFGKASPETIHKVNVQGTQNVIDACVQTGTRLLVYTSSMEVVGPNVKGH 140

  Fly   167 -------DSP-----RNP-----------------------TPNVTIQ-RPRTIYGVSKVHAELI 195
                   |:|     |:|                       .|.||.. ||..|||    ....:
  Rat   141 PFYRGNEDTPYEAIHRHPYPCSKALAEQLVLEANGRKVNGGLPLVTCALRPTGIYG----EGHQV 201

  Fly   196 GEYYYHKFGLDFRCLRFPGVISSDPPG----GGTTDYAVAVFHE-----ALRNGK-YTCYLRPDT 250
            ...:||: ||.|....|..:.:|...|    |......:.|..|     ||..|: |.||.:...
  Rat   202 MRDFYHQ-GLRFGGRLFRAIPASVEHGRVYVGNVAWMHILVARELEQRAALMGGQVYFCYDKSPY 265

  Fly   251 R----LPMMYIEDC---------------------LRALLEFMRAP----NEQLKRRVYNVTAMS 286
            :    ..|.::..|                     |.|||:::..|    ...|......|...:
  Rat   266 KSYEDFNMEFLSPCGLRLIGTHPLLPYWLLVLLAALNALLQWLLRPLVLYTPLLNPYTLAVANTT 330

  Fly   287 FTPEELFAQLGKHVPNLHVTYKPDSRQLIADAWPQVFDDSDAR-RDWHW 334
            ||.....||       .|..|||            :|...::| |..||
  Rat   331 FTVSTNKAQ-------RHFGYKP------------LFSWEESRARTIHW 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdh	NP_649230.1	TDH_SDR_e	47..351	CDD:187580	82/374 (22%)
Hsd3b7	NP_001385604.1	Rossmann-fold NAD(P)(+)-binding proteins	11..361	CDD:473865	82/374 (22%)