DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5955 and Hsd3b6

DIOPT Version :9

Sequence 1:NP_649230.1 Gene:CG5955 / 40268 FlyBaseID:FBgn0036997 Length:367 Species:Drosophila melanogaster
Sequence 2:NP_038849.2 Gene:Hsd3b6 / 15497 MGIID:109598 Length:373 Species:Mus musculus


Alignment Length:347 Identity:76/347 - (21%)
Similarity:123/347 - (35%) Gaps:96/347 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 LITGGLGQLGIECAKLLRTQYGSQNV-ILSDIIKPSQ-------------SVLENGPYIFADILD 99
            |:||..|.||....:||..:...:.: :|....:|..             :|||      .||||
Mouse     7 LVTGAGGFLGQRIVQLLMQEKDLEEIRVLDKFFRPETREQFFNLDTNIKVTVLE------GDILD 65

  Fly   100 FKGLQKIVVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFV-PSTIGA 163
            .:.|:|..  ..|..:||.:|::...|.......:.||::|..|::|...|..:..|: .|::..
Mouse    66 TQYLRKAC--QGISVVIHTAAVIDVTGVIPRQTILDVNLKGTQNLLEACIQASVPAFIFSSSVDV 128

  Fly   164 FGPDSPRNPTPNVTIQRPRTIYGVSKVHAELI--GEYYYHKFGLDFRCLRFPGVISSDPPGGGTT 226
            .||:|.:....|          |..:.|.|.|  ..|.|.|...:...|...|.:...   |||.
Mouse   129 AGPNSYKEIILN----------GNEEEHHESIWSDPYPYSKKMAEKAVLAANGSMLKI---GGTL 180

  Fly   227 DYAVAVFHEALRNGKYTCYLRP----DTRLPMMYIEDCLRALLEFMRAPNEQLKRRVYNVTAMSF 287
                           :||.|||    ..|.|  :|.:.:...|:         .:.:...|....
Mouse   181 ---------------HTCALRPMYIYGERSP--FISNTIITALK---------NKNILGCTGKFS 219

  Fly   288 TPEELF----------AQLG----KHVPNLHVTYKPDSRQLIADAWP-QVFDDSD--ARRDW--- 332
            |...::          |..|    |..||:...:     ..|:|..| |.:||.:  ..::|   
Mouse   220 TANPVYVGNVAWAHILAARGLRDPKKSPNIQGEF-----YYISDDTPHQSYDDLNYTLSKEWGFC 279

  Fly   333 ---HWQHKYDLSNLVDFMIKDV 351
               .|.....|...:.||::.|
Mouse   280 PDSSWSLPVPLLYWLAFMLETV 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5955NP_649230.1 WcaG 47..355 CDD:223528 76/347 (22%)
TDH_SDR_e 47..351 CDD:187580 75/345 (22%)
Hsd3b6NP_038849.2 NADB_Rossmann 5..357 CDD:304358 76/347 (22%)
3Beta_HSD 7..287 CDD:279420 72/331 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0451
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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