DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5955 and Mat2b

DIOPT Version :9

Sequence 1:	NP_649230.1	Gene:	CG5955 / 40268	FlyBaseID:	FBgn0036997	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_598778.1	Gene:	Mat2b / 108645	MGIID:	1913667	Length:	334	Species:	Mus musculus

Alignment Length:	213	Identity:	48/213 - (22%)
Similarity:	73/213 - (34%)	Gaps:	67/213 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PIASQLVQRRAFHQVPRESRPPKILITGGLGQLG--------------IECA-KLLRTQYGSQNV 74
            |...|||:...  .:|  ||  ::||||..|.||              :.|. :..|.::...|
Mouse    14 PGCCQLVEEEV--NIP--SR--RVLITGATGLLGRAVYKEFQQSNWHTVGCGFRRARPKFEQVN- 71

  Fly    75 ILSDIIKPSQSVLENGPYIFADILDFKGLQKIVVDHRIDWLIHFSA-LLSAVGEQNVPLAVRVNI 138
                                  :||.:.:..::.|.:...::|.:| ....|.|.....|.::|:
Mouse    72 ----------------------LLDSEAVHHLIHDFQPHVIVHCAAERRPDVVESQPDAASQLNV 114

  Fly   139 EGVHNVIELAKQYKLRIFVPSTIGAF--------GPDSPRNPTPNVTIQRPRTIYGVSKVHAELI 195
            ....|   |||:       .:.||||        ..|....|.....|..|..:||.:|    |.
Mouse   115 GASGN---LAKE-------AAAIGAFLIYISSDYVFDGTNPPYTEEDIPSPLNLYGKTK----LD 165

  Fly   196 GEYYYHKFGLDFRCLRFP 213
            ||....:..|....||.|
Mouse   166 GEKAVLENNLGAAVLRIP 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5955	NP_649230.1	WcaG	47..355	CDD:223528	41/191 (21%)
CG5955	NP_649230.1	TDH_SDR_e	47..351	CDD:187580	41/191 (21%)
Mat2b	NP_598778.1	dTDP_HR_like_SDR_e	30..316	CDD:187564	41/191 (21%)
		RmlD_sub_bind	31..322	CDD:282214	41/190 (22%)
		Required for interaction with MAT2A. /evidence=ECO:0000250\|UniProtKB:Q9NZL9	319..334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900