DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mag and lipf

DIOPT Version :9

Sequence 1:	NP_649229.1	Gene:	mag / 40267	FlyBaseID:	FBgn0036996	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_998569.1	Gene:	lipf / 406713	ZFINID:	ZDB-GENE-040426-2737	Length:	396	Species:	Danio rerio

Alignment Length:	413	Identity:	140/413 - (33%)
Similarity:	205/413 - (49%)	Gaps:	55/413 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLFSLV---AGLV-----------LAEKSDYCLSEIVKSDERIRSHGYPTETHEVTTQDGYVLTL 58
            |:.|||   :|||           |..:.:..:|||      ||..|||.|..||.|:|||:|::
Zfish     4 LVLSLVILTSGLVQYGQSALDGTGLDPEVNMNISEI------IRHWGYPAEEFEVVTEDGYILSI 62

  Fly    59 FRIPYSHKLKNQNEK-RPPILLQHGLFSNSDCWLSSGPDNSLAYLLADAGYDVWLGNARGNIYSR 122
            .|||  |.:||:||: :|.:.|||||.:....|:::.|:|||.::|||||:|||:||:|||.:|.
Zfish    63 NRIP--HGVKNKNEEVKPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSC 125

  Fly   123 NNIIISLNSHKFWHFDWHEIGTIDIPAMIDYILADTGFDQIHYAGHSQGTTVYLVMLSERPEYNA 187
            .::.:.....::|.|...|:...|:||:|::|...||.:||.|.|||||||:..:..|..||..:
Zfish   126 KHVSLDPRQKEYWKFSHDEMAKKDLPAVINFITKMTGQEQIFYVGHSQGTTIAFMAFSTMPELAS 190

  Fly   188 LIKSGHLLAPCAFFEHGTSFIFNALGPLVGTPGG------------IWNQLLVDTELIPNNNLVN 240
            .||....|||.|               .||....            ||: |....:..|.|.|:.
Zfish   191 KIKMFFALAPVA---------------TVGMTKSPMTKLSVIPEFLIWD-LFGQKDFFPQNELIK 239

  Fly   241 RLVDNSCHLS--NTICNNAFIMFANGGYVNANASSMSVLIETHPAGSSSNQGIHYLQLWKSLKFR 303
            ......|...  :.:|.|.|.:.......|.|.|...|.....|||:|....||:.|..||.|..
Zfish   240 FFATEFCSRKPLSVLCGNVFFLLCGFDEKNLNMSRTPVYTAHCPAGTSVQNMIHWAQAVKSSKLM 304

  Fly   304 QYDWGTKKNNELYGQDLPPDYDLSKIVAPTHLYSSTNDALCGPEDVNTLVENFPHLTEDYRVPVQ 368
            .||:|...|...|.|..||.|::..::.||.::|...|.|..|:||..|:...|.|.  |:..::
Zfish   305 AYDYGRAGNMAHYNQSTPPLYNIQDMMVPTAVWSGGQDTLADPKDVALLLTQIPKLV--YKRDIK 367

  Fly   369 SFNHLDFIIAKNMKELVNDPIIE 391
            .:.|||||...:..:.:.:.:||
Zfish   368 HWEHLDFIWGMDAPQEMYEKMIE 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mag	NP_649229.1	Abhydro_lipase	34..94	CDD:282003	28/60 (47%)
		MhpC	56..366	CDD:223669	110/324 (34%)
		Abhydrolase_5	76..>197	CDD:289465	50/120 (42%)
lipf	NP_998569.1	PLN02872	4..393	CDD:215470	140/413 (34%)
		Abhydro_lipase	36..97	CDD:282003	31/68 (46%)
		Abhydrolase_5	78..242	CDD:289465	62/179 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574730
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.860