DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mag and lipl-8

DIOPT Version :9

Sequence 1:	NP_649229.1	Gene:	mag / 40267	FlyBaseID:	FBgn0036996	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_506641.1	Gene:	lipl-8 / 190108	WormBaseID:	WBGene00013050	Length:	401	Species:	Caenorhabditis elegans

Alignment Length:	406	Identity:	120/406 - (29%)
Similarity:	184/406 - (45%)	Gaps:	70/406 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LSEIVKSDERIRSHGYPTETHEVTTQDGYVLTLFRIPYSHKLKN--QNEKRPPILLQHGLFSNSD 88
            :.|.:.:.:.|..:||..|.|.|||.|||.:.|.|||.....::  ...|||.:...||||.:|.
Worm    19 IEETLDAADTISHYGYTVEKHYVTTDDGYTVQLQRIPVGRDDRSILGCSKRPVVFFMHGLFGSSY 83

  Fly    89 CWLSSGPDNSLAYLLADAGYDVWLGNARGNIYSRNNIIISLNSHKFWHFDWHEIGTIDIPAMIDY 153
            .:|.:.|..|.||:.||||:||||||.||..|..|:...|.|...||:|..:|....|:...|:|
Worm    84 HFLLNLPSQSAAYIFADAGFDVWLGNIRGTEYGLNHTSFSTNGVNFWNFSLYEHSHYDLRQQIEY 148

  Fly   154 ILADTGFDQIHYAGHSQGTTVYLVMLSERP-EYNALIKSGHLLAPCAFFEHGTSFIFNALGPLVG 217
            :|..|..:.:.|.||||||.|....|:|.. .:.:.|:                 :|.||||..|
Worm   149 VLDYTRHESLFYVGHSQGTAVMFARLAEADVTWQSKIR-----------------VFFALGPTAG 196

  Fly   218 TPGGIWNQLLVDTELIPNNNL-----------------------VNRLVDNSCHLSNTICNNAFI 259
                 :.:.|:...|:..|.|                       .::..|        .|::.|.
Worm   197 -----FMKPLMPFTLLEENYLQALIQFALDGKFGILPVEIPRAIASKFAD--------FCSSKFF 248

  Fly   260 MF-ANGGYVNA---------NASSMSVLIETHPAGSSSNQGIHYLQLWKSLKFRQYDWGTKKNNE 314
            .| .:.|:..|         |.|.:.:::...|:.:|:...:|::|::|..:.|:.|.||.:|..
Worm   249 TFLCSAGFKVAAGIETLGQVNDSRIPIILSHFPSATSTLNLLHWMQIFKYHELRRLDLGTARNLI 313

  Fly   315 LYGQDLPPDYDLSKIVAPTHLYSSTNDALCGPEDVNTLV--ENFPHLTEDYRVPVQSFNHLDFII 377
            .|||...|..::..|:|.|.||.|.:|.:....||..::  :..|.|.|.|  .:..|.|.|||:
Worm   314 AYGQKDAPRLEIGNIIAQTILYFSKDDQITDEVDVREIIMKQMGPGLIESY--DLDHFTHFDFIL 376

  Fly   378 AKNMKELVNDPIIERI 393
            .....:.|..||:.||
Worm   377 GLRATDEVYKPIVYRI 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mag	NP_649229.1	Abhydro_lipase	34..94	CDD:282003	24/61 (39%)
		MhpC	56..366	CDD:223669	98/347 (28%)
		Abhydrolase_5	76..>197	CDD:289465	46/121 (38%)
lipl-8	NP_506641.1	PLN02872	26..401	CDD:215470	119/399 (30%)
		Abhydro_lipase	26..89	CDD:282003	24/62 (39%)
		Abhydrolase_5	71..>193	CDD:289465	49/138 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I7224
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.930