DRSC/TRiP Functional Genomics Resources

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Protein Alignment IGLON5 and DIP-delta

DIOPT Version :9

Sequence 1:NP_001094842.1 Gene:IGLON5 / 402665 HGNCID:34550 Length:336 Species:Homo sapiens
Sequence 2:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster


Alignment Length:310 Identity:89/310 - (28%)
Similarity:132/310 - (42%) Gaps:60/310 - (19%)


- Green bases have known domain annotations that are detailed below.


Human    35 FNSPADNYTVCEGDNATLSCFIDEHV--TRVAW--LNRSNILYAGNDRWTSDPRVRLLINTPEEF 95
            |..|..|.||..|.:|.|.|.: ||:  .:|||  ::|..||.......:..||..:.. |...:
  Fly    46 FAQPIPNVTVAVGRDANLPCVV-EHLGGYKVAWIHIDRQMILTIHRHVISRIPRYSITY-TDNTW 108

Human    96 SILITEVGLGDEGLYTCSFQTRHQPYTTQV-YLIVHVPARIVNIS---SPVTVNEGGNVNLLCLA 156
            .:.:.:....|.|.|.|...|  .|..:|| ||.|.||..|::|.   |.|.|.|..|:|:.|.|
  Fly   109 LLHVNQAHQDDRGYYMCQVNT--NPMISQVGYLQVVVPPNILDIESTPSSVAVRENQNINMTCRA 171

Human   157 VGRPEPTVTWRQLRDG-----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
            .|.|.|.:.||: .||           ...:.::|.::.:.|.:.|.|.|:..|||..:. |:|:
  Fly   172 DGFPAPKIIWRR-EDGEEIAVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPSV-SKRI 234

Human   211 LVTVNYPPTI------------TDVTSARTALGRAALLRCEAMAVPPADFQW-YKDDRLLSSGTA 262
            ::.|.:.|.|            ||||           :.|...|.|.|...| |....:|.|   
  Fly   235 ILDVEFSPMIWVPNQLVGAPSGTDVT-----------IDCHTEAHPKAIIYWVYNSVMVLPS--- 285

Human   263 EGLKVQTE------RTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
              .|.:|:      |....|...|:....:|||.|.:.|.||.:..|:|:
  Fly   286 --KKYKTDYTENSYRAHMKLTIRNLQYGDFGNYRCISKNSLGETEGSIRV 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IGLON5NP_001094842.1 Ig 41..129 CDD:416386 28/92 (30%)
Ig strand A' 41..46 CDD:409353 3/4 (75%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 1/3 (33%)
FR2 61..68 CDD:409353 3/8 (38%)
Ig strand C 61..67 CDD:409353 3/7 (43%)
CDR2 69..79 CDD:409353 2/9 (22%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 7/34 (21%)
Ig strand D 84..91 CDD:409353 1/6 (17%)
Ig strand E 94..100 CDD:409353 0/5 (0%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 5/9 (56%)
FR4 122..129 CDD:409353 4/7 (57%)
Ig_3 134..199 CDD:404760 22/78 (28%)
Ig strand B 148..157 CDD:409353 3/8 (38%)
Ig strand C 162..170 CDD:409353 3/7 (43%)
Ig strand F 191..199 CDD:409353 3/7 (43%)
Ig strand G 202..212 CDD:409353 2/9 (22%)
Ig_3 217..295 CDD:404760 23/96 (24%)
putative Ig strand A 218..224 CDD:409353 4/17 (24%)
Ig strand B 234..238 CDD:409353 0/3 (0%)
Ig strand C 247..251 CDD:409353 1/4 (25%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 3/4 (75%)
Ig strand G 301..304 CDD:409353 0/2 (0%)
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 29/95 (31%)
Ig 145..238 CDD:416386 27/94 (29%)
Ig strand A 145..149 CDD:409353 1/3 (33%)
Ig strand A' 154..159 CDD:409353 2/4 (50%)
Ig strand B 165..172 CDD:409353 2/6 (33%)
Ig strand C 178..183 CDD:409353 1/4 (25%)
Ig strand C' 185..187 CDD:409353 1/1 (100%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 1/5 (20%)
Ig strand F 216..223 CDD:409353 3/6 (50%)
Ig strand G 230..238 CDD:409353 2/8 (25%)
Ig 242..333 CDD:416386 27/106 (25%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 3/17 (18%)
Ig strand C 272..277 CDD:409353 1/4 (25%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 1/3 (33%)
Ig strand E 295..305 CDD:409353 2/9 (22%)
Ig strand F 314..322 CDD:409353 4/7 (57%)
Ig strand G 325..334 CDD:409353 3/9 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 45 1.000 Domainoid score I12195
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 141 1.000 Inparanoid score I4481
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8497
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
98.870

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