DRSC/TRiP Functional Genomics Resources

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Protein Alignment IGLON5 and Iglon5

DIOPT Version :9

Sequence 1:NP_001094842.1 Gene:IGLON5 / 402665 HGNCID:34550 Length:336 Species:Homo sapiens
Sequence 2:XP_218634.5 Gene:Iglon5 / 308557 RGDID:1305344 Length:336 Species:Rattus norvegicus


Alignment Length:336 Identity:329/336 - (97%)
Similarity:332/336 - (98%) Gaps:0/336 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MPPPAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVTRVAW 65
            |||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
  Rat     1 MPPPAPGARLRLLAAAALAGLAVISRGLLSQSLEFSSPADNYTVCEGDNATLSCFIDEHVTRVAW 65

Human    66 LNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVH 130
            |||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
  Rat    66 LNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITQVGLGDEGLYTCSFQTRHQPYTTQVYLIVH 130

Human   131 VPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYEC 195
            ||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 VPARIVNISSPVAVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYEC 195

Human   196 VTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSG 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 VTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSG 260

Human   261 TAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPPGLLAL 325
            :||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|.|
  Rat   261 SAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPPGPLTL 325

Human   326 LSALGWLWWRM 336
            ||||.||||||
  Rat   326 LSALSWLWWRM 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IGLON5NP_001094842.1 Ig 41..129 CDD:416386 86/87 (99%)
Ig strand A' 41..46 CDD:409353 4/4 (100%)
Ig strand B 48..56 CDD:409353 7/7 (100%)
CDR1 56..60 CDD:409353 3/3 (100%)
FR2 61..68 CDD:409353 6/6 (100%)
Ig strand C 61..67 CDD:409353 5/5 (100%)
CDR2 69..79 CDD:409353 9/9 (100%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 2/2 (100%)
FR3 80..115 CDD:409353 33/34 (97%)
Ig strand D 84..91 CDD:409353 6/6 (100%)
Ig strand E 94..100 CDD:409353 5/5 (100%)
Ig strand F 107..115 CDD:409353 7/7 (100%)
CDR3 116..120 CDD:409353 3/3 (100%)
Ig strand G 120..129 CDD:409353 8/8 (100%)
FR4 122..129 CDD:409353 6/6 (100%)
Ig_3 134..199 CDD:404760 63/64 (98%)
Ig strand B 148..157 CDD:409353 8/8 (100%)
Ig strand C 162..170 CDD:409353 7/7 (100%)
Ig strand F 191..199 CDD:409353 7/7 (100%)
Ig strand G 202..212 CDD:409353 9/9 (100%)
Ig_3 217..295 CDD:404760 76/77 (99%)
putative Ig strand A 218..224 CDD:409353 5/5 (100%)
Ig strand B 234..238 CDD:409353 3/3 (100%)
Ig strand C 247..251 CDD:409353 3/3 (100%)
Ig strand E 274..278 CDD:409353 3/3 (100%)
Ig strand F 288..293 CDD:409353 4/4 (100%)
Ig strand G 301..304 CDD:409353 2/2 (100%)
Iglon5XP_218634.5 Ig 41..129 CDD:416386 86/87 (99%)
Ig strand A' 41..46 CDD:409353 4/4 (100%)
Ig strand B 48..56 CDD:409353 7/7 (100%)
CDR1 56..60 CDD:409353 3/3 (100%)
FR2 61..68 CDD:409353 6/6 (100%)
Ig strand C 61..67 CDD:409353 5/5 (100%)
CDR2 69..79 CDD:409353 9/9 (100%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 2/2 (100%)
FR3 80..115 CDD:409353 33/34 (97%)
Ig strand D 84..91 CDD:409353 6/6 (100%)
Ig strand E 94..100 CDD:409353 5/5 (100%)
Ig strand F 107..115 CDD:409353 7/7 (100%)
CDR3 116..120 CDD:409353 3/3 (100%)
Ig strand G 120..129 CDD:409353 8/8 (100%)
FR4 122..129 CDD:409353 6/6 (100%)
Ig strand A 132..137 CDD:409353 4/4 (100%)
Ig_3 134..199 CDD:404760 63/64 (98%)
Ig strand A' 140..145 CDD:409353 3/4 (75%)
Ig strand B 148..157 CDD:409353 8/8 (100%)
Ig strand C 163..167 CDD:409353 3/3 (100%)
Ig strand D 174..177 CDD:409353 2/2 (100%)
Ig strand E 178..183 CDD:409353 4/4 (100%)
Ig strand F 191..199 CDD:409353 7/7 (100%)
Ig_3 217..295 CDD:404760 76/77 (99%)
putative Ig strand A 218..224 CDD:409353 5/5 (100%)
Ig strand B 234..238 CDD:409353 3/3 (100%)
Ig strand C 247..251 CDD:409353 3/3 (100%)
Ig strand E 274..278 CDD:409353 3/3 (100%)
Ig strand F 288..293 CDD:409353 4/4 (100%)
Ig strand G 301..304 CDD:409353 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C83679250
Domainoid 1 1.000 183 1.000 Domainoid score I26550
eggNOG 1 0.900 - - E1_KOG3510
HGNC 1 1.500 - -
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H46295
Inparanoid 1 1.050 666 1.000 Inparanoid score I9255
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG43105
OrthoDB 1 1.010 - - D124744at40674
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - oto132452
orthoMCL 1 0.900 - - OOG6_117834
Panther 1 1.100 - - LDO PTHR42757
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1818.270

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