DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment atk and AT1G56140

DIOPT Version :9

Sequence 1:	NP_001262113.1	Gene:	atk / 40266	FlyBaseID:	FBgn0036995	Length:	1535	Species:	Drosophila melanogaster
Sequence 2:	NP_564709.2	Gene:	AT1G56140 / 842066	AraportID:	AT1G56140	Length:	1033	Species:	Arabidopsis thaliana

Alignment Length:	1155	Identity:	228/1155 - (19%)
Similarity:	383/1155 - (33%)	Gaps:	397/1155 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LCIG--INLIRAESCPPSQAILPCRCSLRGKEIQIWCSHSNLPQIMDGLKAVERNIKGRIDELVL 72
            ||.|  |:....:|.|....::.|.||.....|   |..:|       :|.....:.|.|.:.:.
plant    65 LCSGAAIDASVLDSNPAYNPLIKCDCSFENSTI---CRITN-------IKVYAMEVVGSIPQQLW 119

  Fly    73 ENNQLPALPGRFFGSLQIVRLMLRHNSIERVSNGWLNELENGLVEIFVVEPQLRSIPAESLNGMI 137
                                      ::|.::|  ||..:|.|.         .|:| .:|..:.
plant   120 --------------------------TLEYLTN--LNLGQNVLT---------GSLP-PALGNLT 146

  Fly   138 NMLAITIQSEELK-HLPDFSGLLS-LTYLSVQTGALQ-ELPSHLFRHLPKLQHIHITGGSGLTRL 199
            .|..:|.....|. .:|...|||: |..||:.:.... .:|..:.| ..|||.|:|.
plant   147 RMRWMTFGINALSGPIPKEIGLLTDLRLLSISSNNFSGSIPDEIGR-CTKLQQIYID-------- 202

  Fly   200 EAGLFDGL-ISLKNLDLSHNGLNWIHLRALSRLPNLVSLKLSHNQISDVGMVGRI---VKDLEHL 260
            .:||..|| :|..||                       ::|....|:|:.:.|:|   :.|...|
plant   203 SSGLSGGLPVSFANL-----------------------VELEQAWIADMELTGQIPDFIGDWTKL 244

  Fly   261 KKLRLDNNLITVIEDGSFVDLPNLSELHLND--NRITELQYGAFLRTPQLKTIYLQNNLIRRIHP 323
            ..||:....::.....||.:|.:|:||.|.|  |..:.|::...:::  |..:.|:||.:....|
plant   245 TTLRILGTGLSGPIPASFSNLTSLTELRLGDISNGNSSLEFIKDMKS--LSILVLRNNNLTGTIP 307

  Fly   324 ESLLQASGSGVEAVHMYNNEIGHVEALRALLDALPRLRYLDMSGNLLSELPYGALRGHGTLEQLH 388
            .::.:.|.                            ||.||:|.|.|          |||:..
plant   308 SNIGEYSS----------------------------LRQLDLSFNKL----------HGTIPA-- 332

  Fly   389 LNHNHLRLIERDALMAMPALRELRMRNNSLSSDLP--------------------LPFW-NLPGL 432
                        :|..:..|..|.:.||:|:..||                    ||.| :||.|
plant   333 ------------SLFNLRQLTHLFLGNNTLNGSLPTQKGQSLSNVDVSYNDLSGSLPSWVSLPNL 385

  Fly   433 KGLDLAQNQFA--RVDSQLLAGLPSLRR-----------LDLSEN-----------GLIE----- 468
             .|:|..|.|.  .:|:::|:||..|::           .|.|.|           .:.|
plant   386 -NLNLVANNFTLEGLDNRVLSGLNCLQKNFPCNRGKGIYSDFSINCGGPEIRSVTEAVFEREDED 449

  Fly   469 LAPNSF-------------------RHNPLLETLNISSNELTKIHSSTLIHLERLFEVDASYNQL 514
            |.|.||                   .:|..:.|   |.::......|.|....||     |.:.|
plant   450 LGPASFVVSAGQRWAASSVGLFAGSSNNIYIST---SQSQFVNTLDSELFQSARL-----SASSL 506

  Fly   515 KSVIAGLPRIVERISLKGNQITSLPAAASKDLQLPNLRMLDLSQNRIEQLPRHGFQGAMELRVLS 579
            :....||..       .|..:|         ||...:::|..:.|....|.|..|...::.|::.
plant   507 RYYGLGLEN-------GGYTVT---------LQFAEIQILGSTSNTWRGLGRRRFDIYVQGRLVE 555

  Fly   580 LAQNELRQLKDTSFIGIQRLELLHLQENQL-------GEAD-----ERALLPLAELRNL------ 626
            ...:..|...|::...:||....::.:|.|       |:..     :.|..||......
plant   556 KDFDVRRTAGDSTVRAVQREYKANVSQNHLEIHLFWAGKGTCCIPIQGAYGPLISAVGATPDFTP 620

  Fly   627 ---NLQSNKLEAITDN-------------------FFSNNSRLEQLDLSRNLIRSISPTAF---D 666
               |...:|.:::|..                   |.....|....|....|...:.|..|   :
plant   621 TVGNRPPSKGKSMTGTIVGVIVGVGLLSIISGVVIFIIRKRRKRYTDDEEILSMDVKPYTFTYSE 685

  Fly   667 TQRSLEYLDLSGNALLDISVG---LGNLNNLRDIDLSYNQISRIQ------SDVIG----GWRNV 718
            .:.:.:..|.| |.|.:...|   .|.||:.|::.:....:...|      ::::.    ..||:
plant   686 LKSATQDFDPS-NKLGEGGFGPVYKGKLNDGREVAVKLLSVGSRQGKGQFVAEIVAISAVQHRNL 749

  Fly   719 VEI---------RLSNNLIVE------LQQGTFRNLPKLQYLDLSSNEIRNVEPGALKGLDELQE 768
            |::         ||   |:.|      |.|..|..  |..:||.|:.  ..:..|..:||..|.|
plant   750 VKLYGCCYEGEHRL---LVYEYLPNGSLDQALFGE--KTLHLDWSTR--YEICLGVARGLVYLHE 807

  Fly   769 --------------FVLADNKLV-ELKDHVFEELPSLLASHFQ---YNKLRYISPESFHN----- 810
                          .:|.|:||| ::.|....:|.....:|..   ...:.|::||....
plant   808 EARLRIVHRDVKASNILLDSKLVPKVSDFGLAKLYDDKKTHISTRVAGTIGYLAPEYAMRGHLTE 872

  Fly   811 -----ANSLVFLNLSNNHFRNMENIGLRSMRNLE-VLDLSTNG--VKLVSTMPLKALNWLVELKM 867
                 |..:|.|.|.:....:.||:.......|| ..:|...|  |:|:.       :.|.|..|
plant   873 KTDVYAFGVVALELVSGRPNSDENLEDEKRYLLEWAWNLHEKGREVELID-------HQLTEFNM 930

  Fly   868 DNNQICRIQGSPFETMPRLRVLSMRNNQLRSIKERTFRNVRGNIAILDVDGNPIDCNCEMQWLSV 932
            :..:  |:.|...       :.:..::.||....|....:.|::.:.||...|       .:|:.
plant   931 EEGK--RMIGIAL-------LCTQTSHALRPPMSRVVAMLSGDVEVSDVTSKP-------GYLTD 979

  Fly   933 WLQE---------------------TNFPYP----GPKCQDGRLLRSARM 957
            |..:                     |:|..|    .|:..|.|.:..|:|
plant   980 WRFDDTTASSISGFPLRNTQASESFTSFVAPRSEISPRNNDARPMLGAQM 1029

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
atk	NP_001262113.1	leucine-rich repeat	69..89	CDD:275380	0/19 (0%)
		leucine-rich repeat	90..113	CDD:275380	4/22 (18%)
		leucine-rich repeat	115..138	CDD:275380	4/22 (18%)
		leucine-rich repeat	139..160	CDD:275380	6/21 (29%)
		leucine-rich repeat	161..184	CDD:275380	5/23 (22%)
		LRR_8	183..244	CDD:290566	13/61 (21%)
		leucine-rich repeat	185..209	CDD:275380	8/24 (33%)
		LRR_4	209..247	CDD:289563	5/37 (14%)
		leucine-rich repeat	210..233	CDD:275380	2/22 (9%)
		leucine-rich repeat	234..259	CDD:275380	6/27 (22%)
		LRR_RI	250..492	CDD:238064	66/315 (21%)
		LRR_8	259..318	CDD:290566	17/60 (28%)
		leucine-rich repeat	260..283	CDD:275380	6/22 (27%)
		leucine-rich repeat	284..307	CDD:275380	7/24 (29%)
		leucine-rich repeat	308..359	CDD:275380	6/50 (12%)
		leucine-rich repeat	334..348	CDD:275378	0/13 (0%)
		LRR_8	358..418	CDD:290566	15/59 (25%)
		leucine-rich repeat	360..383	CDD:275380	8/22 (36%)
		leucine-rich repeat	384..407	CDD:275380	1/22 (5%)
		LRR_8	406..466	CDD:290566	25/104 (24%)
		leucine-rich repeat	408..431	CDD:275380	11/43 (26%)
		leucine-rich repeat	432..455	CDD:275380	9/24 (38%)
		LRR_RI	447..705	CDD:238064	61/349 (17%)
		LRR_8	454..514	CDD:290566	17/105 (16%)
		leucine-rich repeat	456..476	CDD:275380	9/65 (14%)
		leucine-rich repeat	480..501	CDD:275380	4/20 (20%)
		leucine-rich repeat	505..517	CDD:275378	2/11 (18%)
		leucine-rich repeat	525..550	CDD:275380	4/24 (17%)
		LRR_8	549..609	CDD:290566	11/59 (19%)
		leucine-rich repeat	551..574	CDD:275380	5/22 (23%)
		leucine-rich repeat	575..598	CDD:275380	3/22 (14%)
		leucine-rich repeat	599..622	CDD:275380	6/34 (18%)
		LRR_8	622..681	CDD:290566	12/89 (13%)
		leucine-rich repeat	623..646	CDD:275380	4/50 (8%)
		LRR_RI	647..896	CDD:238064	61/310 (20%)
		leucine-rich repeat	647..670	CDD:275380	4/25 (16%)
		leucine-rich repeat	671..693	CDD:275380	7/24 (29%)
		leucine-rich repeat	694..717	CDD:275380	2/32 (6%)
		LRR_8	716..776	CDD:290566	21/88 (24%)
		leucine-rich repeat	718..741	CDD:275380	8/37 (22%)
		leucine-rich repeat	742..763	CDD:275380	4/20 (20%)
		LRR_8	765..824	CDD:290566	17/86 (20%)
		leucine-rich repeat	766..789	CDD:275380	9/37 (24%)
		leucine-rich repeat	790..813	CDD:275380	5/35 (14%)
		leucine-rich repeat	814..835	CDD:275380	5/20 (25%)
		leucine-rich repeat	838..861	CDD:275380	6/25 (24%)
		LRR_8	862..921	CDD:290566	11/58 (19%)
		leucine-rich repeat	862..885	CDD:275380	5/22 (23%)
		leucine-rich repeat	886..906	CDD:275380	3/19 (16%)
		TPKR_C2	919..>946	CDD:301599	7/51 (14%)
AT1G56140	NP_564709.2	leucine-rich repeat	124..147	CDD:275380	8/34 (24%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		leucine-rich repeat	172..195	CDD:275380	5/23 (22%)
		leucine-rich repeat	196..243	CDD:275380	17/77 (22%)
		leucine-rich repeat	220..241	CDD:275380	5/20 (25%)
		leucine-rich repeat	244..267	CDD:275380	6/22 (27%)
		leucine-rich repeat	268..291	CDD:275380	7/22 (32%)
		leucine-rich repeat	292..315	CDD:275380	5/22 (23%)
		leucine-rich repeat	316..339	CDD:275380	11/46 (24%)
		leucine-rich repeat	340..364	CDD:275380	7/23 (30%)
		Malectin	426..612	CDD:288557	38/209 (18%)
		STKc_IRAK	699..961	CDD:270968	57/284 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000