DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment atk and AT1G53420

DIOPT Version :9

Sequence 1:	NP_001262113.1	Gene:	atk / 40266	FlyBaseID:	FBgn0036995	Length:	1535	Species:	Drosophila melanogaster
Sequence 2:	NP_175747.2	Gene:	AT1G53420 / 841777	AraportID:	AT1G53420	Length:	953	Species:	Arabidopsis thaliana

Alignment Length:	561	Identity:	117/561 - (20%)
Similarity:	202/561 - (36%)	Gaps:	170/561 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 NLLSELPYGALRGHGTLEQLHLNHNHLRLIERDALMAMPALRELRMRNNSLSSDLPLPFWNLPGL 432
            ||...|| ..|.|...|:::.|:.|:|..........:| |..:.:..|.|:..:|..|.|:..|
plant    74 NLQGSLP-KELVGLPLLQEIDLSRNYLNGSIPPEWGVLP-LVNIWLLGNRLTGPIPKEFGNITTL 136

  Fly   433 KGLDLAQNQFARVDSQLLAGLPSLRRLDLSENGLIELAPNSFRHNPLLETLNISSNELTKIHSST 497
            ..|.|..||.:......|..||:::::.||.|......|::|.....|....:|.|:|    |.|
plant   137 TSLVLEANQLSGELPLELGNLPNIQQMILSSNNFNGEIPSTFAKLTTLRDFRVSDNQL----SGT 197

  Fly   498 L-------IHLERLFEVDASYNQLKSVIAGLPRIVERISLKGNQITSLPAAASKDLQLPNLRMLD 555
            :       ..||||| :.||         ||             :..:|.|.:..::|.:||:.|
plant   198 IPDFIQKWTKLERLF-IQAS---------GL-------------VGPIPIAIASLVELKDLRISD 239

  Fly   556 LSQNRIEQLPRHGFQGAMELRVLSLAQNELRQLKDTSFIGIQRLELLHLQENQLGEADERALLPL 620
            |:.      |...|.             :||.:|        ::|.|
plant   240 LNG------PESPFP-------------QLRNIK--------KMETL------------------ 259

  Fly   621 AELRNLNLQSNKLEAITDNFFSNNSRLEQLDLSRNLIRSISPTAFDTQRSLEYLDLSGNALLDIS 685
             .|||.||..:     ..::....:..:.||||.|.:....|..:...|...|:..:|| :|:.|
plant   260 -ILRNCNLTGD-----LPDYLGKITSFKFLDLSFNKLSGAIPNTYINLRDGGYIYFTGN-MLNGS 317

  Fly   686 VGLGNLNNLRDIDLSYNQISRIQSDVIGGWRNVV----------------------EIRLSNNLI 728
            |....:|....||||||..|...::.:..:.||:                      |:.::..:.
plant   318 VPDWMVNKGYKIDLSYNNFSVDPTNAVCKYNNVLSCMRNYQCPKTFNALHINCGGDEMSINGTIY 382

  Fly   729 -----------VELQQGTFRN----------LPKLQYLDLSSNEIRNVEPGALKGLDELQEFVLA 772
                       .|.:.|.|.|          :|:...::.:|:|:..|:.|.         :..|
plant   383 ESDKYDRLESWYESRNGWFSNNVGVFVDDKHVPERVTIESNSSELNVVDFGL---------YTQA 438

  Fly   773 DNKLVELKDHVFEELPSLLASHFQYNKLRYISPESFHNANSLVFLNLSNNHFRNMENIGLR---- 833
            ....:.|..:      :|...:..||.             :|.|..:..|...|.:::|.|
plant   439 RISAISLTYY------ALCLENGNYNV-------------NLHFAEIMFNGNNNYQSLGRRFFDI 484

  Fly   834 -SMRNLEVLDLSTN------GVKLVSTMPLKALNWLVELKM 867
             ..|.|||.|.:..      |..::.|.|::..:..:|:::
plant   485 YIQRKLEVKDFNIAKEAKDVGNVVIKTFPVEIKDGKLEIRL 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
atk	NP_001262113.1	leucine-rich repeat	69..89	CDD:275380
		leucine-rich repeat	90..113	CDD:275380
		leucine-rich repeat	115..138	CDD:275380
		leucine-rich repeat	139..160	CDD:275380
		leucine-rich repeat	161..184	CDD:275380
		LRR_8	183..244	CDD:290566
		leucine-rich repeat	185..209	CDD:275380
		LRR_4	209..247	CDD:289563
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..259	CDD:275380
		LRR_RI	250..492	CDD:238064	34/123 (28%)
		LRR_8	259..318	CDD:290566
		leucine-rich repeat	260..283	CDD:275380
		leucine-rich repeat	284..307	CDD:275380
		leucine-rich repeat	308..359	CDD:275380
		leucine-rich repeat	334..348	CDD:275378
		LRR_8	358..418	CDD:290566	13/49 (27%)
		leucine-rich repeat	360..383	CDD:275380	6/14 (43%)
		leucine-rich repeat	384..407	CDD:275380	4/22 (18%)
		LRR_8	406..466	CDD:290566	18/59 (31%)
		leucine-rich repeat	408..431	CDD:275380	6/22 (27%)
		leucine-rich repeat	432..455	CDD:275380	7/22 (32%)
		LRR_RI	447..705	CDD:238064	62/264 (23%)
		LRR_8	454..514	CDD:290566	19/66 (29%)
		leucine-rich repeat	456..476	CDD:275380	5/19 (26%)
		leucine-rich repeat	480..501	CDD:275380	6/27 (22%)
		leucine-rich repeat	505..517	CDD:275378	3/11 (27%)
		leucine-rich repeat	525..550	CDD:275380	3/24 (13%)
		LRR_8	549..609	CDD:290566	11/59 (19%)
		leucine-rich repeat	551..574	CDD:275380	6/22 (27%)
		leucine-rich repeat	575..598	CDD:275380	3/22 (14%)
		leucine-rich repeat	599..622	CDD:275380	2/22 (9%)
		LRR_8	622..681	CDD:290566	15/58 (26%)
		leucine-rich repeat	623..646	CDD:275380	5/22 (23%)
		LRR_RI	647..896	CDD:238064	53/275 (19%)
		leucine-rich repeat	647..670	CDD:275380	6/22 (27%)
		leucine-rich repeat	671..693	CDD:275380	6/21 (29%)
		leucine-rich repeat	694..717	CDD:275380	7/22 (32%)
		LRR_8	716..776	CDD:290566	13/102 (13%)
		leucine-rich repeat	718..741	CDD:275380	6/65 (9%)
		leucine-rich repeat	742..763	CDD:275380	4/20 (20%)
		LRR_8	765..824	CDD:290566	8/58 (14%)
		leucine-rich repeat	766..789	CDD:275380	2/22 (9%)
		leucine-rich repeat	790..813	CDD:275380	3/22 (14%)
		leucine-rich repeat	814..835	CDD:275380	6/25 (24%)
		leucine-rich repeat	838..861	CDD:275380	7/28 (25%)
		LRR_8	862..921	CDD:290566	1/6 (17%)
		leucine-rich repeat	862..885	CDD:275380	1/6 (17%)
		leucine-rich repeat	886..906	CDD:275380
		TPKR_C2	919..>946	CDD:301599
AT1G53420	NP_175747.2	leucine-rich repeat	89..110	CDD:275380	4/20 (20%)
		leucine-rich repeat	112..135	CDD:275380	6/22 (27%)
		leucine-rich repeat	136..159	CDD:275380	7/22 (32%)
		leucine-rich repeat	160..183	CDD:275380	5/22 (23%)
		leucine-rich repeat	184..207	CDD:275380	6/26 (23%)
		leucine-rich repeat	208..231	CDD:275380	11/45 (24%)
		leucine-rich repeat	232..255	CDD:275380	10/49 (20%)
		leucine-rich repeat	256..279	CDD:275380	7/46 (15%)
		leucine-rich repeat	280..301	CDD:275380	6/20 (30%)
		leucine-rich repeat	304..325	CDD:275380	6/21 (29%)
		leucine-rich repeat	327..345	CDD:275380	7/17 (41%)
		Malectin	366..548	CDD:288557	30/188 (16%)
		STKc_IRAK	630..897	CDD:270968
		TyrKc	630..895	CDD:197581
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000