DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment atk and RLP19

DIOPT Version :10

Sequence 1:NP_649228.1 Gene:atk / 40266 FlyBaseID:FBgn0036995 Length:1535 Species:Drosophila melanogaster
Sequence 2:NP_179112.1 Gene:RLP19 / 815997 AraportID:AT2G15080 Length:983 Species:Arabidopsis thaliana


Alignment Length:1007 Identity:224/1007 - (22%)
Similarity:362/1007 - (35%) Gaps:269/1007 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   157 GLLSLTYLSVQT-GALQELPSHLFRHL--PKLQHIHITGGSGLTRLEAGLFDGLISLKNLDLSHN 218
            |.::|::|.:.. ..|.|..:.. |||  |......:...:....||...||..|.||....::|
plant     4 GYITLSFLIILIFNFLDEFAAST-RHLCDPDQSDAILEFKNEFETLEESCFDSNIPLKTESWTNN 67

  Fly   219 G--LNWIHLRALSRLPNLVSLKLS----HNQISDVGMVGRIVKDLEHLKKLRLDNNLITVIEDGS 277
            .  ..|..::..::..:::.|.||    ..|::....:.|: ..|..|..|.|.||........|
plant    68 SDCCYWDGIKCDAKFGDVIELDLSFSCLRGQLNSNSSLFRL-PQLRFLTTLDLSNNDFIGQIPSS 131

  Fly   278 FVDLPNLSELHLNDNR--------ITELQYGAFLRTPQLKTIYLQNNLIRRIHPESLLQASGSGV 334
            ...|.||:.|.|:.|.        |..|.:..|:.       :..||...:| |.||...|    
plant   132 LETLSNLTTLDLSRNHFSGRIPSSIGNLSHLIFVD-------FSHNNFSGQI-PSSLGYLS---- 184

  Fly   335 EAVHM------YNNEIGHVEALRALLDALPRLRYLDMSGN-LLSELPYGALRGHGTLEQLHLNHN 392
               |:      |||..|.|.:....|..|..||   :|.| ...|||                  
plant   185 ---HLTSFNLSYNNFSGRVPSSIGNLSYLTTLR---LSRNSFFGELP------------------ 225

  Fly   393 HLRLIERDALMAMPALRELRMRNNSLSSDLPLPFWNLPGLKGLDLAQNQFARVDSQLLAGLPSLR 457
                   .:|.::..|.:|.:..|.....:|....||..|..:||.:|.|.......|..|..|.
plant   226 -------SSLGSLFHLTDLILDTNHFVGKIPSSLGNLSHLTSIDLHKNNFVGEIPFSLGNLSCLT 283

  Fly   458 RLDLSENGLIELAPNSFRHNPLLETLNISSNELTKIHSSTLIHLERLFEVDASYNQLKSVIAGLP 522
            ...||:|.::...|:||.:...|:.||:.||:|:......|::|.:|                  
plant   284 SFILSDNNIVGEIPSSFGNLNQLDILNVKSNKLSGSFPIALLNLRKL------------------ 330

  Fly   523 RIVERISLKGNQIT-SLPAAASKDLQLPNLRMLDLSQNRIE-QLPRHGFQGAMELRVLSLAQNEL 585
               ..:||..|::| :||:..|   .|.||::.|.::|... .||...| ....|:.::|..|:|
plant   331 ---STLSLFNNRLTGTLPSNMS---SLSNLKLFDATENHFTGPLPSSLF-NIPSLKTITLENNQL 388

  Fly   586 R-QLKDTSFIGIQRLELLHLQENQLGEADERALLPLAELRNLNLQSNKLEAITD-NFFSNNSRLE 648
            . .|...:......|.:|.|..|.......|::..|..|:.|:|.:...:.:.| ..||:...:|
plant   389 NGSLGFGNISSYSNLTVLRLGNNNFRGPIHRSISKLVNLKELDLSNYNTQGLVDFTIFSHLKSIE 453

  Fly   649 QLDLSR-NLIRSISP-TAFDTQRSLEYLDLSGNALLDISVGLGNLNN------------------ 693
            .|:||. |...:|.. ....:.:.|:.|||||:.:  .:....:|:|                  
plant   454 YLNLSHLNTTTTIDMYEILSSFKLLDTLDLSGSHV--STTNKSSLSNSSLVLISQLYLSGCGITE 516

  Fly   694 ----LRD------IDLSYNQISRIQSDVIGGWRNVVE----IRLSNNLIVELQQGT--------- 735
                ||.      :|:|.|:|    ...:.||..::.    :.||||..:..::.|         
plant   517 FPKFLRSQELMLTLDISNNKI----KGQVPGWLWMLPVLNYVNLSNNTFIGFERSTKLGLTSIQE 577

  Fly   736 ---------------------FRNLPKLQYLDLSSNEIRNVEPGALKGLDE--LQEFVLADNKLV 777
                                 ...||.|..||.|:|:.....|..:..:..  ||...|..|:|.
plant   578 PPAMRQLFCSNNNFTGNIPSFICELPYLSTLDFSNNKFNGSIPTCMGNIQSPYLQALNLRHNRLS 642

  Fly   778 E-LKDHVFEELPSLLASHFQYNKLRYISPESFHNANSLVFLNLSNNHFRNMENIGLRSMRNLEVL 841
            . |.:::||.|.||...|   |:|....|.|..:.:||..||:.:|...:...:.|.|::.|:||
plant   643 GLLPENIFESLISLDVGH---NQLVGKLPRSLSHISSLGLLNVESNKISDTFPLWLSSLQELQVL 704

  Fly   842 DLSTN--------------------GVKLVSTMPLK-ALNWLVELKMDNNQ-------------- 871
            .|.:|                    |.:...|:|.. .:||.....:|.|:              
plant   705 VLRSNAFYGPIEKTQFSKLRIIDISGNQFNGTLPANFFVNWTAMFSLDENEDQSNGETMSNMYMS 769

  Fly   872 ----------------------------ICRIQGSPFE--------TMPRLRVLSMRNNQLRSIK 900
                                        :....|:.||        .:..|.||::.||.|....
plant   770 TDYFYFDSMVLMNKGVEMELERVLKVFTVIDFSGNKFEGEIPKSIGLLKELHVLNLSNNALSGHI 834

  Fly   901 ERTFRNVRGNIAILDVDGNPI--DCNCEMQWLSVWLQETNFPY-------PG------PKC---Q 947
            ..:..|:.. :..|||..|.:  :...|:..|: :|...||.:       ||      .||   :
plant   835 ASSMGNLMA-LESLDVSQNKLSGEIPQELGKLT-YLAYMNFSHNQLVGLLPGGTQFQTQKCSSFE 897

  Fly   948 DGRLLRSARMERSLCVGADIYGNERTDGNQLP 979
            |...|....:|: :|   ||:|......:..|
plant   898 DNHGLYGPSLEK-IC---DIHGKTPQQSDMAP 925

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
atkNP_649228.1 leucine-rich repeat 886..906 CDD:275380 6/19 (32%)
PCC 891..>936 CDD:188093 11/46 (24%)
leucine-rich repeat 69..89 CDD:275380
leucine-rich repeat 90..113 CDD:275380
LRR 93..530 CDD:443914 91/396 (23%)
leucine-rich repeat 115..138 CDD:275380
leucine-rich repeat 139..160 CDD:275380 1/2 (50%)
leucine-rich repeat 161..184 CDD:275380 7/25 (28%)
leucine-rich repeat 185..209 CDD:275380 4/23 (17%)
leucine-rich repeat 210..233 CDD:275380 4/24 (17%)
leucine-rich repeat 234..259 CDD:275380 6/28 (21%)
leucine-rich repeat 260..283 CDD:275380 7/22 (32%)
leucine-rich repeat 284..307 CDD:275380 7/30 (23%)
leucine-rich repeat 308..359 CDD:275380 15/56 (27%)
leucine-rich repeat 334..348 CDD:275378 5/19 (26%)
PLN00113 359..>824 CDD:215061 125/536 (23%)
leucine-rich repeat 360..383 CDD:275380 7/23 (30%)
leucine-rich repeat 384..407 CDD:275380 1/22 (5%)
leucine-rich repeat 408..431 CDD:275380 6/22 (27%)
leucine-rich repeat 432..455 CDD:275380 7/22 (32%)
leucine-rich repeat 456..476 CDD:275380 7/19 (37%)
leucine-rich repeat 480..501 CDD:275380 7/20 (35%)
leucine-rich repeat 505..517 CDD:275378 0/11 (0%)
leucine-rich repeat 525..550 CDD:275380 8/25 (32%)
leucine-rich repeat 551..574 CDD:275380 6/23 (26%)
leucine-rich repeat 575..598 CDD:275380 5/23 (22%)
leucine-rich repeat 599..622 CDD:275380 6/22 (27%)
leucine-rich repeat 623..646 CDD:275380 6/23 (26%)
leucine-rich repeat 647..670 CDD:275380 6/24 (25%)
leucine-rich repeat 671..693 CDD:275380 7/21 (33%)
leucine-rich repeat 694..717 CDD:275380 8/28 (29%)
leucine-rich repeat 718..741 CDD:275380 6/56 (11%)
leucine-rich repeat 742..763 CDD:275380 6/20 (30%)
leucine-rich repeat 766..789 CDD:275380 9/23 (39%)
leucine-rich repeat 790..813 CDD:275380 6/22 (27%)
leucine-rich repeat 814..835 CDD:275380 5/20 (25%)
leucine-rich repeat 838..861 CDD:275380 8/43 (19%)
leucine-rich repeat 862..885 CDD:275380 5/72 (7%)
RLP19NP_179112.1 PLN00113 3..>646 CDD:215061 163/717 (23%)
leucine-rich repeat 114..137 CDD:275380 7/22 (32%)
leucine-rich repeat 138..161 CDD:275380 6/22 (27%)
leucine-rich repeat 162..185 CDD:275380 8/37 (22%)
leucine-rich repeat 186..209 CDD:275380 6/22 (27%)
leucine-rich repeat 210..233 CDD:275380 9/50 (18%)
leucine-rich repeat 234..257 CDD:275380 6/22 (27%)
leucine-rich repeat 258..281 CDD:275380 7/22 (32%)
leucine-rich repeat 282..305 CDD:275380 7/22 (32%)
leucine-rich repeat 306..329 CDD:275380 8/22 (36%)
leucine-rich repeat 330..351 CDD:275380 8/44 (18%)
leucine-rich repeat 354..377 CDD:275380 6/23 (26%)
leucine-rich repeat 378..402 CDD:275380 5/23 (22%)
leucine-rich repeat 403..424 CDD:275380 5/20 (25%)
leucine-rich repeat 427..451 CDD:275380 6/23 (26%)
leucine-rich repeat 452..477 CDD:275380 6/24 (25%)
leucine-rich repeat 507..526 CDD:275380 2/18 (11%)
leucine-rich repeat 527..550 CDD:275380 6/26 (23%)
leucine-rich repeat 551..574 CDD:275380 5/22 (23%)
leucine-rich repeat 575..604 CDD:275380 1/28 (4%)
PLN03150 <604..692 CDD:178695 27/90 (30%)
leucine-rich repeat 605..630 CDD:275380 6/24 (25%)
leucine-rich repeat 631..655 CDD:275380 9/23 (39%)
PLN03150 <656..739 CDD:178695 20/85 (24%)
leucine-rich repeat 656..676 CDD:275380 6/22 (27%)
leucine-rich repeat 677..700 CDD:275380 6/22 (27%)
leucine-rich repeat 701..722 CDD:275380 5/20 (25%)
leucine-rich repeat 723..795 CDD:275380 7/71 (10%)
leucine-rich repeat 796..819 CDD:275380 3/22 (14%)
PLN03150 <808..962 CDD:178695 28/124 (23%)
leucine-rich repeat 820..843 CDD:275380 7/22 (32%)
leucine-rich repeat 844..867 CDD:275380 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

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