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Protein Alignment atk and LRFN1

DIOPT Version :10

Sequence 1:	NP_649228.1	Gene:	atk / 40266	FlyBaseID:	FBgn0036995	Length:	1535	Species:	Drosophila melanogaster
Sequence 2:	NP_065913.1	Gene:	LRFN1 / 57622	HGNCID:	29290	Length:	771	Species:	Homo sapiens

Alignment Length:	803	Identity:	180/803 - (22%)
Similarity:	287/803 - (35%)	Gaps:	189/803 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   716 RNVVEIRLSNNLIVELQQGTFRNLPKLQYLDLSSNEIRNVEPGALKGLDELQEFVLADNKLVELK 780
            |.|||:||::|.|..:::..|.|:..|.:|.||.|.|..|..||
Human    65 RRVVELRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGA--------------------- 108

  Fly   781 DHVFEELPSLLASHFQYNKLRYISPESFHNANSLVFLNLSNNHFRNMENIGLRS-MRNLEVLDLS 844
               |.:|.:|.|.|...|:|..:..:......:|..|.|.||..|.:|:....: :..:|.||||
Human   109 ---FADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQIRRVESAAFDAFLSTVEDLDLS 170

  Fly   845 TNGVKLVSTMPLKALNWLVELK---MDNNQICRIQGSPFETMPRLRVLSMRNNQLRSI-KERTFR 905
            .|.::   .:|.:|:..:|.|.   :|:|.|..|....|..:.:|..|.|.:|:|..: .:..|.
Human   171 YNNLE---ALPWEAVGQMVNLNTLTLDHNLIDHIAEGTFVQLHKLVRLDMTSNRLHKLPPDGLFL 232

  Fly   906 NVRG------NIAILDVDGNPIDCNCEMQWLSVWLQETNFPYPGPKCQDGRLLRSARMERSLCVG 964
            ..:|      ....:...|||:.||||:.||.                  ||.|...:|  .|.
Human   233 RSQGTGPKPPTPLTVSFGGNPLHCNCELLWLR------------------RLTREDDLE--TCA- 276

  Fly   965 ADIYGNERTDGNQLPLLNEH-GDVFQRDLPDDFNDECEAGEGTRLPGDRPLV--GESEYFYDQYV 1026
                            ..|| .|.:...:|:: ...||....||..|.|.||  |::.....:.|
Human   277 ----------------TPEHLTDRYFWSIPEE-EFLCEPPLITRQAGGRALVVEGQAVSLRCRAV 324

  Fly  1027 DATE------APDTTHSAISTSQRPKPTPTINSNIDLNNTILHTKYFNRKPQPGSG---SPFTFF 1082
            ...|      |||......|:..|.:...|::..|   .|:..:..|.......:|   :|....
Human   325 GDPEPVVHWVAPDGRLLGNSSRTRVRGDGTLDVTI---TTLRDSGTFTCIASNAAGEATAPVEVC 386

  Fly  1083 GYPLPSVSLGRFF-------GFGDRGRKQRTDSNDDMPATHRMAHISLPSGR-----------GK 1129
            ..|||.::.....       |..|.....|..:||. .|..|:....|.|..           ..
Human   387 VVPLPLMAPPPAAPPPLTEPGSSDIATPGRPGANDS-AAERRLVAAELTSNSVLIRWPAQRPVPG 450

  Fly  1130 TRMYQPNSAEFEKYLKDQQKQEKLNIARNRYVDTDSTTSSMED----ALSNESGSA--AT-TVGV 1187
            .||||   .::...:.|......:......::..|.......|    |:.::..:|  || .||.
Human   451 IRMYQ---VQYNSSVDDSLVYRMIPSTSQTFLVNDLAAGRAYDLCVLAVYDDGATALPATRVVGC 512

  Fly  1188 FR-TTFREPSSIERGGFRPIVPAHVGGFMPVHDPQQRRGLVEVVNITGNPSEIVQGIGQRKFIPI 1251
            .: ||..:|:..     ||:....:||.|             ::.|.|   .||..:  ..|| :
Human   513 VQFTTAGDPAPC-----RPLRAHFLGGTM-------------IIAIGG---VIVASV--LVFI-V 553

  Fly  1252 STQARPKPTKSSGESSETATYEVTETTPDITTTTPLMQRIATSTTKASTTTTRSTTTTSTTQVTP 1316
            ....|.| ....|:|.....          :.:.|.:..:.:.|..|.|...::       ...|
Human   554 LLMIRYK-VYGDGDSRRVKG----------SRSLPRVSHVCSQTNGAGTGAAQA-------PALP 600

  Fly  1317 AENNASSSTELDSQYDDEDLEAQSVTLLRPPPLVQTTTAE-------------TILLIPPAEEHV 1368
            |:::..:..|::||      .|.:|.:.......:|.:||             |.|.:.|:||..
Human   601 AQDHYEALREVESQ------AAPAVAVEAKAMEAETASAEPEVVLGRSLGGSATSLCLLPSEETS 659

  Fly  1369 AQIKSRSWVTTTTPQSPSDNQVTLAGPTSTVPPPPPASPPLRGGGRSTITKVYTPYQQQVAQP-- 1431
            .: :||:.|.....:|.:....|.|.||..:.|...|:.| |...|.:....|....|..:.|
Human   660 GE-ESRAAVGPRRSRSGALEPPTSAPPTLALVPGGAAARP-RPQQRYSFDGDYGALFQSHSYPRR 722

  Fly  1432 -TAEEYQRTTP--SGDNEGVASE 1451
             ...:..|:||  .|...|.|.|
Human   723 ARRTKRHRSTPHLDGAGGGAAGE 745

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.