DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment atk and si:dkey-90m5.4

DIOPT Version :9

Sequence 1:NP_001262113.1 Gene:atk / 40266 FlyBaseID:FBgn0036995 Length:1535 Species:Drosophila melanogaster
Sequence 2:NP_001038237.1 Gene:si:dkey-90m5.4 / 553466 ZFINID:ZDB-GENE-041014-250 Length:327 Species:Danio rerio


Alignment Length:333 Identity:88/333 - (26%)
Similarity:136/333 - (40%) Gaps:99/333 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   370 LSELPYGALRGHGTLEQLHLNHNHLRLIERDALMAMPALRELRMRNNSLSSDLPLPFWNLPGLKG 434
            ||..|...|....|  .|.:...:|.::..:.|.|:|.|.||.:..|.|||        ||    
Zfish    45 LSHFPGDGLPPSTT--SLTIQFTNLTVLTSEHLRAVPLLEELHLPGNKLSS--------LP---- 95

  Fly   435 LDLAQNQFARVDSQLLAGLPSLRRLDLSENGLIELAPNSFRHNPLLETLNISSNELTKIHSSTLI 499
                        :.:|..|..|..:||::|.|.||....|||.||| .|.:..|.::.||.....
Zfish    96 ------------ADILKDLKYLHTIDLTDNELRELPEYVFRHAPLL-NLVLKDNRISNIHPDWFP 147

  Fly   500 HLERLFEVDASYNQLKSVIAGLPRIVERISLKGNQITSLPAAASKDLQLPNLRMLDLSQNRIEQL 564
            :...|..:|                     |.|||:...|.|..::|:  :|::|.||||:||:|
Zfish   148 NNSNLTWLD---------------------LSGNQLMKFPMAQLQNLR--HLKVLHLSQNKIEEL 189

  Fly   565 PRHGFQGAMELRVLSLAQNELRQLKDTSFIGIQRLELLHLQENQLGEADERALLPLAELRNLNLQ 629
            |    .|.::...                    .||.|:|.:|::...|.:|             
Zfish   190 P----VGCLDAHT--------------------ALERLYLDQNKIQTLDVKA------------- 217

  Fly   630 SNKLEAITDNFFSNNSRLEQLDLSRNLIRSISPTAFDTQRSLEYLDLSGNALLDISVGLGNLNNL 694
                       ||.::.|..:.|.:|.|.|:.||.|...:.|||:|||.|.|..:|.|:.::|. 
Zfish   218 -----------FSGSTNLTHIFLQKNRIDSLPPTVFQELKRLEYVDLSDNRLQFLSPGILDINT- 270

  Fly   695 RDIDLSYN 702
            ..::|::|
Zfish   271 SWVELTFN 278

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
atkNP_001262113.1 leucine-rich repeat 69..89 CDD:275380
leucine-rich repeat 90..113 CDD:275380
leucine-rich repeat 115..138 CDD:275380
leucine-rich repeat 139..160 CDD:275380
leucine-rich repeat 161..184 CDD:275380
LRR_8 183..244 CDD:290566
leucine-rich repeat 185..209 CDD:275380
LRR_4 209..247 CDD:289563
leucine-rich repeat 210..233 CDD:275380
leucine-rich repeat 234..259 CDD:275380
LRR_RI 250..492 CDD:238064 36/121 (30%)
LRR_8 259..318 CDD:290566
leucine-rich repeat 260..283 CDD:275380
leucine-rich repeat 284..307 CDD:275380
leucine-rich repeat 308..359 CDD:275380
leucine-rich repeat 334..348 CDD:275378
LRR_8 358..418 CDD:290566 14/47 (30%)
leucine-rich repeat 360..383 CDD:275380 4/12 (33%)
leucine-rich repeat 384..407 CDD:275380 4/22 (18%)
LRR_8 406..466 CDD:290566 16/59 (27%)
leucine-rich repeat 408..431 CDD:275380 8/22 (36%)
leucine-rich repeat 432..455 CDD:275380 2/22 (9%)
LRR_RI 447..705 CDD:238064 69/256 (27%)
LRR_8 454..514 CDD:290566 19/59 (32%)
leucine-rich repeat 456..476 CDD:275380 8/19 (42%)
leucine-rich repeat 480..501 CDD:275380 5/20 (25%)
leucine-rich repeat 505..517 CDD:275378 1/11 (9%)
leucine-rich repeat 525..550 CDD:275380 7/24 (29%)
LRR_8 549..609 CDD:290566 16/59 (27%)
leucine-rich repeat 551..574 CDD:275380 11/22 (50%)
leucine-rich repeat 575..598 CDD:275380 0/22 (0%)
leucine-rich repeat 599..622 CDD:275380 7/22 (32%)
LRR_8 622..681 CDD:290566 17/58 (29%)
leucine-rich repeat 623..646 CDD:275380 2/22 (9%)
LRR_RI 647..896 CDD:238064 21/56 (38%)
leucine-rich repeat 647..670 CDD:275380 8/22 (36%)
leucine-rich repeat 671..693 CDD:275380 10/21 (48%)
leucine-rich repeat 694..717 CDD:275380 2/9 (22%)
LRR_8 716..776 CDD:290566
leucine-rich repeat 718..741 CDD:275380
leucine-rich repeat 742..763 CDD:275380
LRR_8 765..824 CDD:290566
leucine-rich repeat 766..789 CDD:275380
leucine-rich repeat 790..813 CDD:275380
leucine-rich repeat 814..835 CDD:275380
leucine-rich repeat 838..861 CDD:275380
LRR_8 862..921 CDD:290566
leucine-rich repeat 862..885 CDD:275380
leucine-rich repeat 886..906 CDD:275380
TPKR_C2 919..>946 CDD:301599
si:dkey-90m5.4NP_001038237.1 LRR_8 55..115 CDD:404697 21/85 (25%)
leucine-rich repeat 57..80 CDD:275380 5/24 (21%)
leucine-rich repeat 81..104 CDD:275380 11/46 (24%)
PPP1R42 102..279 CDD:411060 68/250 (27%)
leucine-rich repeat 105..126 CDD:275380 9/20 (45%)
leucine-rich repeat 128..151 CDD:275380 6/23 (26%)
leucine-rich repeat 152..175 CDD:275380 9/45 (20%)
leucine-rich repeat 176..199 CDD:275380 11/46 (24%)
leucine-rich repeat 200..223 CDD:275380 9/46 (20%)
leucine-rich repeat 224..247 CDD:275380 8/22 (36%)
leucine-rich repeat 248..271 CDD:275380 11/23 (48%)
TPKR_C2 278..319 CDD:417692 1/1 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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