Protein Alignment atk and tsku

DIOPT Version :10

• Sequence 1: NP_649228.1
• Gene: atk / 40266
• FlyBaseID: FBgn0036995
• Length: 1535
• Species: Drosophila melanogaster
• Sequence 2: NP_001011330.1
• Gene: tsku / 496792
• XenbaseID: XB-GENE-493206
• Length: 350
• Species: Xenopus tropicalis
• Alignment Length: 377
• Identity: 100/377 - (26%)
• Similarity: 153/377 - (40%)
• Gaps: 116/377 - (30%)

  Fly   213 LDLSHNGLNWIHLRALS--RLPNLVSLKLSHNQISDVGMVGRIVKDLEHLKKLRLDNNLITVIED 275
            ||||.||:..|:...||  ....|::|.||||||..:..  .....|.:|:.|.|.:||:..:.|
 Frog    64 LDLSANGIKRINESVLSGPGYTTLINLNLSHNQIVRISF--STFSKLRYLESLDLSHNLLETLPD 126

  Fly   276 GSFVDLPNLSELHLNDNRITELQYGAFLRTPQLK--TIYLQNNLIRRIHPESLLQASGSGVEAVH 338
            |||: ...|:||.|:.|::.|:..|||....|.:  ||.|.||.||.||         .|.|.
 Frog   127 GSFL-YSRLTELDLSSNKLLEVGIGAFTLKSQGRSMTINLGNNNIRSIH---------RGAER-- 179

  Fly   339 MYNNEIGHVEALRALLDALPRLRYLDMSGNLLSELPYGALRGHGTLEQLHLNHNHLRLIERDALM 403
                             .:|.:..|.:|||.|..:|           .||
 Frog   180 -----------------PVPNIHSLTLSGNDLLSVP-----------DLH--------------- 201

  Fly   404 AMPALRELRMRNNSLSSDLPLPFWNLPGLKGLDLAQNQFARVDSQLLAGLPSLRRLDLSE-NGLI 467
                                    .:| |:.|||.:|..|:::.:...||..|..|.||: ..|.
 Frog   202 ------------------------GIP-LRHLDLDRNPLAKIEKESFLGLEGLTHLSLSDLPNLR 241

  Fly   468 ELAPNSFRHNPLLETLNISSN-ELTKIHSSTLIHLERLFEVDASYNQLKSVIAGLPRIVERISLK 531
            |::|.||:..|.|..|::||| :|..:.|.....|:.|.|::.:|    |.:|.||:.:.
 Frog   242 EVSPYSFKTLPSLLDLDLSSNPQLKSLSSDMFFGLDSLQELNLAY----SGVAALPKDIM----- 297

  Fly   532 GNQITSLPAAASKDLQLPNLRMLDLSQN-----RIEQLPRHGFQGAMELRVL 578
                          |.||:::.:...:|     .:::.|.|..:|.:...||
 Frog   298 --------------LNLPSMKSITWGENIRCSKTVKESPFHAQKGRVREEVL 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atk	NP_649228.1	leucine-rich repeat	886..906	CDD:275380
		PCC	891..>936	CDD:188093
		leucine-rich repeat	69..89	CDD:275380
		leucine-rich repeat	90..113	CDD:275380
		LRR	93..530	CDD:443914	91/322 (28%)
		leucine-rich repeat	115..138	CDD:275380
		leucine-rich repeat	139..160	CDD:275380
		leucine-rich repeat	161..184	CDD:275380
		leucine-rich repeat	185..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380	9/21 (43%)
		leucine-rich repeat	234..259	CDD:275380	9/24 (38%)
		leucine-rich repeat	260..283	CDD:275380	9/22 (41%)
		leucine-rich repeat	284..307	CDD:275380	9/22 (41%)
		leucine-rich repeat	308..359	CDD:275380	11/52 (21%)
		leucine-rich repeat	334..348	CDD:275378	1/13 (8%)
		PLN00113	359..>824	CDD:215061	51/227 (22%)
		leucine-rich repeat	360..383	CDD:275380	6/22 (27%)
		leucine-rich repeat	384..407	CDD:275380	2/22 (9%)
		leucine-rich repeat	408..431	CDD:275380	0/22 (0%)
		leucine-rich repeat	432..455	CDD:275380	8/22 (36%)
		leucine-rich repeat	456..476	CDD:275380	9/20 (45%)
		leucine-rich repeat	480..501	CDD:275380	7/21 (33%)
		leucine-rich repeat	505..517	CDD:275378	2/11 (18%)
		leucine-rich repeat	525..550	CDD:275380	2/24 (8%)
		leucine-rich repeat	551..574	CDD:275380	4/27 (15%)
		leucine-rich repeat	575..598	CDD:275380	2/4 (50%)
		leucine-rich repeat	599..622	CDD:275380
		leucine-rich repeat	623..646	CDD:275380
		leucine-rich repeat	647..670	CDD:275380
		leucine-rich repeat	671..693	CDD:275380
		leucine-rich repeat	694..717	CDD:275380
		leucine-rich repeat	718..741	CDD:275380
		leucine-rich repeat	742..763	CDD:275380
		leucine-rich repeat	766..789	CDD:275380
		leucine-rich repeat	790..813	CDD:275380
		leucine-rich repeat	814..835	CDD:275380
		leucine-rich repeat	838..861	CDD:275380
		leucine-rich repeat	862..885	CDD:275380
tsku	NP_001011330.1	LRRNT	21..63	CDD:214470
		LRR 1	60..81		8/16 (50%)
		leucine-rich repeat	61..86	CDD:275380	9/21 (43%)
		LRR	<62..>236	CDD:443914	69/253 (27%)
		LRR 2	86..107		8/22 (36%)
		leucine-rich repeat	87..110	CDD:275380	9/24 (38%)
		LRR 3	110..131		9/21 (43%)
		leucine-rich repeat	111..133	CDD:275380	9/22 (41%)
		LRR 4	133..154		9/20 (45%)
		leucine-rich repeat	134..159	CDD:275380	10/24 (42%)
		LRR 5	159..180		11/48 (23%)
		leucine-rich repeat	160..183	CDD:275380	11/50 (22%)
		LRR 6	183..203		8/69 (12%)
		leucine-rich repeat	184..203	CDD:275380	8/68 (12%)
		LRR 7	204..225		7/21 (33%)
		LRR_8	205..286	CDD:404697	28/80 (35%)
		leucine-rich repeat	205..228	CDD:275380	8/22 (36%)
		LRR 8	228..250		9/21 (43%)
		leucine-rich repeat	229..278	CDD:275380	18/48 (38%)
		LRR 9	253..275		7/21 (33%)
		LRR 10	278..299		7/43 (16%)
		leucine-rich repeat	279..302	CDD:275380	9/45 (20%)