Protein Alignment atk and tril

DIOPT Version :10

• Sequence 1: NP_649228.1
• Gene: atk / 40266
• FlyBaseID: FBgn0036995
• Length: 1535
• Species: Drosophila melanogaster
• Sequence 2: XP_009292463.1
• Gene: tril / 448885
• ZFINID: ZDB-GENE-131218-1
• Length: 758
• Species: Danio rerio
• Alignment Length: 802
• Identity: 166/802 - (20%)
• Similarity: 279/802 - (34%)
• Gaps: 227/802 - (28%)

  Fly   572 AMELRVLSLAQNELRQLKDTSFIGIQRLELLHLQENQLGEADERALLPLAELRNLNLQSNKLEAI 636
            |.::||||||.|.:..:....|                        :...:|..||||.|::.:|
Zfish    57 AEDVRVLSLAGNFIHNISAFDF------------------------MRYGDLMRLNLQFNQIRSI 97

  Fly   637 TDNFFSNNSRLEQLDLSRNLIRSISPTAFDTQRSLEYLDLSGNALLDISVGLGNLNNLRDIDLSY 701
            ....|...|:||:|.|..|||.:|.|                          |.|.:|:.:.:.|
Zfish    98 HPESFKKLSKLEELFLGNNLISTIQP--------------------------GTLQSLKKLTILY 136

  Fly   702 ---NQISRIQSDVIGGWRNVVEIRLSNNLIVELQQGTFRNLPKLQYLDLSSNEIRNVEPGALKGL 763
               |:|:...........::|::||..|.|..|::..|..||.|.:|.|.||.:|.::..|...|
Zfish   137 SNNNEINECIPKSFTHLNSLVKLRLDGNSIEVLKESVFEGLPNLMFLHLESNHLRRIDRNAFLRL 201

  Fly   764 DELQEFVLADNKLVELKD-HVFEELPSLLASHFQYNKLRYISPESFHNANSLVFLNLSNNHFRNM 827
            .:||...|:|||..||:| .:|.:|.||.......|::|::....|.:...|..|:||:|....:
Zfish   202 SKLQFLNLSDNKQTELQDVFMFSDLKSLKTLLIAGNQIRHVGNHVFQSLKKLSKLSLSHNKISKL 266

  Fly   828 ENIGLRSMRNLEVLDLSTNGVKLVSTMPLKALNWLVELKMDNNQICRIQGSPFETMPRLRVLSMR 892
            .|...:.:..:....:..|.:..:....|..|..:..|...:|.|..:....|..:..|::|.::
Zfish   267 GNEAFKGLGRVREFMIDRNELTEIPAGLLDPLERIEHLDFSDNHISLVDQGAFGHLSHLKILKLK 331

  Fly   893 NNQLRSIKERTFRNVRGNIAILDVDGNPIDCNCEMQWLSVWLQETNFPYPGPKCQDGRLLR-SAR 956
            ||:|.::....|.: .|.:..::::||...|:|.|:.|..|:...:        ..|:||. ..|
Zfish   332 NNRLMNLSGSIFAS-NGGLFHVELNGNNWTCDCRMEKLKSWMTHAH--------SQGKLLTVFVR 387

  Fly   957 MERSLCVGADIYGNERTD---GNQL----------PL---LNEHGDVFQRDLPDDFNDECEAGEG 1005
                 |:...:...:..|   ..||          ||   :...|.|.:..:..:..::.|..:.
Zfish   388 -----CLHPPVLAGKYLDYVSNLQLKNMSGFCESEPLSQPMESRGAVVETPVFKEEREKREKHDE 447

  Fly  1006 TRLPGDRPLVGESEYFYDQYVDATEAPDTT----HSAISTSQRPKPTPTINSNIDLNNTILHTKY 1066
            ..:.||:.:.|               |.||    ......|.|||||        ..||
Zfish   448 VEVQGDQGVQG---------------PGTTLKRKKKRKLASSRPKPT--------ARNT------ 483

  Fly  1067 FNRKPQPGSGSPFTFFGYPLPSVSLGRFFGFGDRGRKQRTDSNDDMPATHRMAHISLPSGRGKTR 1131
                   |:||....|      .::..|.                             .|...:.
Zfish   484 -------GNGSLSDLF------TTMAMFL-----------------------------EGHNYST 506

  Fly  1132 MYQPNSAEFEKYLKDQQKQE--------------KLNIARNRYVDTDSTTSSMEDALSNESGSAA 1182
            .......:|...|:||.|.|              :|:|......|..|.|:::..:.:.::|.|.
Zfish   507 FALTPQEQFNLPLQDQSKYEDSKTAGIADACQFNRLSILNVSVEDITSITATVRWSTTPDTGLAH 571

  Fly  1183 TTVGVFRT-------TFREPSSIERGG---------FRP------------------IVPA-HVG 1212
            .....||.       .||.|..:...|         .||                  :.|. |..
Zfish   572 GKELHFRVLFDRFGHAFRFPRYVYTDGSDRAVTLQELRPESTYITCVESVVDGTLCKVAPRDHCT 636

  Fly  1213 GF---MPVHDPQQRRGLVEVVNITGNP--SEIVQGIGQRKFIPISTQARPKPTKSSGESSETATY 1272
            ||   :|....:....|:.|..:..|.  ..:|.|:...:.:    :.|.:..|||..:.....|
Zfish   637 GFVTLLPSVTTEVNLQLITVAALAANALLLLLVGGVWLGRVL----KRRIRSRKSSAHAHVRHMY 697

  Fly  1273 EVTETTPDITTTTPLMQRIATS 1294
                     :|..|....:||:
Zfish   698 ---------STRHPFRSTVATT 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atk	NP_649228.1	leucine-rich repeat	886..906	CDD:275380	6/19 (32%)
		PCC	891..>936	CDD:188093	12/44 (27%)
		leucine-rich repeat	69..89	CDD:275380
		leucine-rich repeat	90..113	CDD:275380
		LRR	93..530	CDD:443914
		leucine-rich repeat	115..138	CDD:275380
		leucine-rich repeat	139..160	CDD:275380
		leucine-rich repeat	161..184	CDD:275380
		leucine-rich repeat	185..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..259	CDD:275380
		leucine-rich repeat	260..283	CDD:275380
		leucine-rich repeat	284..307	CDD:275380
		leucine-rich repeat	308..359	CDD:275380
		leucine-rich repeat	334..348	CDD:275378
		PLN00113	359..>824	CDD:215061	71/255 (28%)
		leucine-rich repeat	360..383	CDD:275380
		leucine-rich repeat	384..407	CDD:275380
		leucine-rich repeat	408..431	CDD:275380
		leucine-rich repeat	432..455	CDD:275380
		leucine-rich repeat	456..476	CDD:275380
		leucine-rich repeat	480..501	CDD:275380
		leucine-rich repeat	505..517	CDD:275378
		leucine-rich repeat	525..550	CDD:275380
		leucine-rich repeat	551..574	CDD:275380	1/1 (100%)
		leucine-rich repeat	575..598	CDD:275380	8/22 (36%)
		leucine-rich repeat	599..622	CDD:275380	0/22 (0%)
		leucine-rich repeat	623..646	CDD:275380	8/22 (36%)
		leucine-rich repeat	647..670	CDD:275380	9/22 (41%)
		leucine-rich repeat	671..693	CDD:275380	2/21 (10%)
		leucine-rich repeat	694..717	CDD:275380	4/25 (16%)
		leucine-rich repeat	718..741	CDD:275380	8/22 (36%)
		leucine-rich repeat	742..763	CDD:275380	7/20 (35%)
		leucine-rich repeat	766..789	CDD:275380	11/23 (48%)
		leucine-rich repeat	790..813	CDD:275380	4/22 (18%)
		leucine-rich repeat	814..835	CDD:275380	6/20 (30%)
		leucine-rich repeat	838..861	CDD:275380	3/22 (14%)
		leucine-rich repeat	862..885	CDD:275380	4/22 (18%)
tril	XP_009292463.1	LRRNT	25..56	CDD:214470
		leucine-rich repeat	60..83	CDD:275380	8/46 (17%)
		LRR	<83..>242	CDD:443914	56/184 (30%)
		leucine-rich repeat	84..107	CDD:275380	8/22 (36%)
		leucine-rich repeat	108..131	CDD:275380	12/48 (25%)
		leucine-rich repeat	132..155	CDD:275380	3/22 (14%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..203	CDD:275380	8/22 (36%)
		leucine-rich repeat	204..228	CDD:275380	11/23 (48%)
		leucine-rich repeat	229..252	CDD:275380	4/22 (18%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		LRR_8	259..311	CDD:404697	8/51 (16%)
		leucine-rich repeat	277..298	CDD:275380	2/20 (10%)
		LRR_8	300..358	CDD:404697	12/58 (21%)
		leucine-rich repeat	301..324	CDD:275380	4/22 (18%)
		leucine-rich repeat	325..348	CDD:275380	6/23 (26%)
		FN3	546..614	CDD:214495	13/67 (19%)