Protein Alignment atk and Xrra1

DIOPT Version :10

• Sequence 1: NP_649228.1
• Gene: atk / 40266
• FlyBaseID: FBgn0036995
• Length: 1535
• Species: Drosophila melanogaster
• Sequence 2: XP_017177834.1
• Gene: Xrra1 / 446101
• MGIID: 2181647
• Length: 788
• Species: Mus musculus
• Alignment Length: 488
• Identity: 106/488 - (21%)
• Similarity: 186/488 - (38%)
• Gaps: 128/488 - (26%)

  Fly   145 QSEELKHLPDFSGLL---------SLTYLSVQTGALQELPSHLFRHLPKLQHIHITGGSGLTRLE 200
            |::.|.|:.|.|.||         .|..::|......:.....|:|...:  |:|.....|..|:
Mouse    79 QADVLGHILDRSFLLKHHSARKPSDLCTINVSGMKFSKAKEKDFKHFTSV--IYINASENLLPLD 141

  Fly   201 AGLFDGLISLKNLDLSHNGLNWIHLRALSRLPNLVSLKLSHNQ-----ISDVGMVGRIVKDLEHL 260
              :|.....||.|:|:.||:..:::: ......|..|.||.|.     |.|:|:       |.||
Mouse   142 --VFHTFPVLKELELAFNGIKMVYVK-YGDFKTLEFLDLSFNSLTEEAICDLGI-------LPHL 196

  Fly   261 KKLRLDNNLITVI--------EDGSFVDL---------PNLSELHLNDNRITELQ-YGAFLRTPQ 307
            :.|.|..|.:|.:        ::.|...|         |.|..|.|:||:::... :.:.....:
Mouse   197 RVLLLTGNGLTSLPPNMAVKEQEASMTSLTSKKYILRFPALETLMLDDNKLSNPSCFASLAGLRR 261

  Fly   308 LKTIYL-QNNLIRRIHPESLLQASGSGVEAVHMYNNEIGHVEALRALL------DALPRLRYLDM 365
            ||.:.| ||.::|..:.:.:....|||.......|.:    :.|:..:      |..|....|.|
Mouse   262 LKKLSLDQNKIVRIPYLQQIQLRDGSGDWVTEGPNPQ----KELQPQMWIFETPDEQPNYTVLPM 322

  Fly   366 SGNL-LSELPYGALRGHGTLEQLHLNHNHLRLIERDALMAMPALRELRMRNNSLSSDLPLPFWNL 429
            ..:: .:|:.:.:..|..|.|.       .::.....:..:..::.|:.||.:|:.    ||
Mouse   323 KKDVDRTEVVFSSYPGFSTSET-------AKVCSLPPMFEILPVKSLKARNQTLAP----PF--- 373

  Fly   430 PGLKGLDLAQNQFARVDSQLLAGL-PSLRRLDLSENGLIELAPNSFRHNPLLETLNISSNELTKI 493
            |.|:.|.||.|:.|:.|:.|.|.| |||..|             .|.:|||:            .
Mouse   374 PELRYLSLAYNKIAKEDAVLPAALFPSLCEL-------------VFHNNPLV------------A 413

  Fly   494 HSSTLIHLERLFEVDASYNQLKSVIAGLPRIVERISLKGNQITSLPAAASKDLQLPNLRMLDLSQ 558
            |:..:..|.:.|..|.         .|: |:|.:..:|......:|...|:.:           :
Mouse   414 HTRGIPPLLKSFLQDR---------LGI-RLVRKKLVKPKHHMLMPRKESRKV-----------K 457

  Fly   559 NRIEQLPRHGFQGAMELRVLSLAQNELRQLKDT 591
            ..|.::|:|           ||..:.|..:.|:
Mouse   458 TYIPKVPKH-----------SLVPHHLNMITDS 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atk	NP_649228.1	leucine-rich repeat	886..906	CDD:275380
		PCC	891..>936	CDD:188093
		leucine-rich repeat	69..89	CDD:275380
		leucine-rich repeat	90..113	CDD:275380
		LRR	93..530	CDD:443914	96/425 (23%)
		leucine-rich repeat	115..138	CDD:275380
		leucine-rich repeat	139..160	CDD:275380	7/23 (30%)
		leucine-rich repeat	161..184	CDD:275380	4/22 (18%)
		leucine-rich repeat	185..209	CDD:275380	5/23 (22%)
		leucine-rich repeat	210..233	CDD:275380	6/22 (27%)
		leucine-rich repeat	234..259	CDD:275380	9/29 (31%)
		leucine-rich repeat	260..283	CDD:275380	7/39 (18%)
		leucine-rich repeat	284..307	CDD:275380	5/23 (22%)
		leucine-rich repeat	308..359	CDD:275380	12/57 (21%)
		leucine-rich repeat	334..348	CDD:275378	1/13 (8%)
		PLN00113	359..>824	CDD:215061	48/235 (20%)
		leucine-rich repeat	360..383	CDD:275380	4/23 (17%)
		leucine-rich repeat	384..407	CDD:275380	1/22 (5%)
		leucine-rich repeat	408..431	CDD:275380	6/22 (27%)
		leucine-rich repeat	432..455	CDD:275380	10/23 (43%)
		leucine-rich repeat	456..476	CDD:275380	3/19 (16%)
		leucine-rich repeat	480..501	CDD:275380	1/20 (5%)
		leucine-rich repeat	505..517	CDD:275378	2/11 (18%)
		leucine-rich repeat	525..550	CDD:275380	4/24 (17%)
		leucine-rich repeat	551..574	CDD:275380	3/22 (14%)
		leucine-rich repeat	575..598	CDD:275380	4/17 (24%)
		leucine-rich repeat	599..622	CDD:275380
		leucine-rich repeat	623..646	CDD:275380
		leucine-rich repeat	647..670	CDD:275380
		leucine-rich repeat	671..693	CDD:275380
		leucine-rich repeat	694..717	CDD:275380
		leucine-rich repeat	718..741	CDD:275380
		leucine-rich repeat	742..763	CDD:275380
		leucine-rich repeat	766..789	CDD:275380
		leucine-rich repeat	790..813	CDD:275380
		leucine-rich repeat	814..835	CDD:275380
		leucine-rich repeat	838..861	CDD:275380
		leucine-rich repeat	862..885	CDD:275380
Xrra1	XP_017177834.1	LRR	<120..>280	CDD:443914	42/171 (25%)
		leucine-rich repeat	149..171	CDD:275378	6/22 (27%)
		leucine-rich repeat	172..195	CDD:275378	9/29 (31%)
		leucine-rich repeat	196..227	CDD:275378	7/30 (23%)
		leucine-rich repeat	237..261	CDD:275378	5/23 (22%)
		PRK15370	<239..>423	CDD:185268	50/226 (22%)
		leucine-rich repeat	262..275	CDD:275378	5/12 (42%)