DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment atk and CG5810

DIOPT Version :9

Sequence 1:NP_001262113.1 Gene:atk / 40266 FlyBaseID:FBgn0036995 Length:1535 Species:Drosophila melanogaster
Sequence 2:NP_650952.2 Gene:CG5810 / 42513 FlyBaseID:FBgn0038866 Length:428 Species:Drosophila melanogaster


Alignment Length:458 Identity:116/458 - (25%)
Similarity:188/458 - (41%) Gaps:91/458 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   107 WLNELENGLVEIFVVEPQ-LRSIPAESL----NGMINM-----LAITIQSEEL-KHLPDFSGLLS 160
            :||.:...::.....|.| |..|..:||    |...|:     .|:...||.: |||..:..|: 
  Fly     6 YLNYILIAVIAFATCESQKLEEIAIDSLDCRENTCTNLKYPSASAVAYFSENVTKHLRKYETLV- 69

  Fly   161 LTYLSVQTGALQELPSHLFRHLPKLQHIHITGGSGLTRLEAGLFDGLISLKNLDLSHNGLNWIHL 225
                 :.:..|..||..:|.:||:|...|:. ...|.::|:..|||..:||.|:...|.|..:..
  Fly    70 -----LHSSDLANLPRKIFLNLPQLVEFHVL-ECELQQIESVCFDGAKNLKRLNFGGNALRVLDS 128

  Fly   226 RALSRLPNLVSLKLSHNQISDVGMVGRIVKDLEHLKKLRLDNNLITVIEDGSFVDLPNLSELHLN 290
            ........|..|.||.||:.|:...  |.:.|::|:|:.|.||.:..:....|..|.:|..::::
  Fly   129 NTFELATQLEELNLSDNQLEDLPTT--IFRPLKNLQKINLSNNRLITLSQHIFSQLGSLKSINVD 191

  Fly   291 DNRITELQYGAFLRTPQ--LKTIYLQNNLIRRIHPESLLQASGSGVEAVHMYNNEIGHVEALRAL 353
            .|::.||. |...|..:  |.....|:|.:.|| |.::.:              ||.|:.     
  Fly   192 SNQLVELP-GELFRDQRKHLSEFSAQSNQLVRI-PFNIFR--------------EIDHLS----- 235

  Fly   354 LDALPRLRYLDMSGNLLSELPYGALRGHGTLEQLHLNHNHLRLIERDA------LMAMPALRELR 412
            |...|:||.|.:|..               :.:|...:..|..:|.|.      |.|.|.|.||:
  Fly   236 LSFNPQLRRLHLSAK---------------INELEATNCDLESVELDGRVIGVQLEANPKLHELK 285

  Fly   413 MRNNSLSSDLPLPFWNLPGLKGLDLAQNQFARVDSQLLAGLPSLRRLDLSENGLIELAP----NS 473
            :   |...|          |:.|.||.....|:|  .|:....|..||:::  ::.||.    .|
  Fly   286 I---SQPQD----------LEHLYLANTNLYRLD--FLSKASKLVDLDVTD--IVNLADLPKITS 333

  Fly   474 FRHNPLLETLNISSNELTKIHSSTLIHLERLFEVDASYNQLKSV-IAGLPR--IVERISLKGNQI 535
            .:.   ||.|:.:.:.||..|...|.||:.|..::.|:.:.|.: |..|..  .||...|...|:
  Fly   334 AKG---LERLSFTYDNLTSNHMDMLPHLKDLNYLEISHEKGKEIFIKDLDEDFFVEEAELNCGQL 395

  Fly   536 TSL 538
            ..|
  Fly   396 ADL 398

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
atkNP_001262113.1 leucine-rich repeat 69..89 CDD:275380
leucine-rich repeat 90..113 CDD:275380 2/5 (40%)
leucine-rich repeat 115..138 CDD:275380 7/27 (26%)
leucine-rich repeat 139..160 CDD:275380 7/26 (27%)
leucine-rich repeat 161..184 CDD:275380 5/22 (23%)
LRR_8 183..244 CDD:290566 18/60 (30%)
leucine-rich repeat 185..209 CDD:275380 7/23 (30%)
LRR_4 209..247 CDD:289563 11/37 (30%)
leucine-rich repeat 210..233 CDD:275380 5/22 (23%)
leucine-rich repeat 234..259 CDD:275380 9/24 (38%)
LRR_RI 250..492 CDD:238064 59/253 (23%)
LRR_8 259..318 CDD:290566 16/60 (27%)
leucine-rich repeat 260..283 CDD:275380 7/22 (32%)
leucine-rich repeat 284..307 CDD:275380 6/22 (27%)
leucine-rich repeat 308..359 CDD:275380 10/50 (20%)
leucine-rich repeat 334..348 CDD:275378 3/13 (23%)
LRR_8 358..418 CDD:290566 15/65 (23%)
leucine-rich repeat 360..383 CDD:275380 4/22 (18%)
leucine-rich repeat 384..407 CDD:275380 6/28 (21%)
LRR_8 406..466 CDD:290566 16/59 (27%)
leucine-rich repeat 408..431 CDD:275380 5/22 (23%)
leucine-rich repeat 432..455 CDD:275380 7/22 (32%)
LRR_RI 447..705 CDD:238064 26/99 (26%)
LRR_8 454..514 CDD:290566 17/63 (27%)
leucine-rich repeat 456..476 CDD:275380 6/23 (26%)
leucine-rich repeat 480..501 CDD:275380 7/20 (35%)
leucine-rich repeat 505..517 CDD:275378 2/11 (18%)
leucine-rich repeat 525..550 CDD:275380 5/14 (36%)
LRR_8 549..609 CDD:290566
leucine-rich repeat 551..574 CDD:275380
leucine-rich repeat 575..598 CDD:275380
leucine-rich repeat 599..622 CDD:275380
LRR_8 622..681 CDD:290566
leucine-rich repeat 623..646 CDD:275380
LRR_RI 647..896 CDD:238064
leucine-rich repeat 647..670 CDD:275380
leucine-rich repeat 671..693 CDD:275380
leucine-rich repeat 694..717 CDD:275380
LRR_8 716..776 CDD:290566
leucine-rich repeat 718..741 CDD:275380
leucine-rich repeat 742..763 CDD:275380
LRR_8 765..824 CDD:290566
leucine-rich repeat 766..789 CDD:275380
leucine-rich repeat 790..813 CDD:275380
leucine-rich repeat 814..835 CDD:275380
leucine-rich repeat 838..861 CDD:275380
LRR_8 862..921 CDD:290566
leucine-rich repeat 862..885 CDD:275380
leucine-rich repeat 886..906 CDD:275380
TPKR_C2 919..>946 CDD:301599
CG5810NP_650952.2 leucine-rich repeat 65..88 CDD:275380 6/28 (21%)
LRR_8 87..147 CDD:290566 18/60 (30%)
leucine-rich repeat 89..112 CDD:275380 7/23 (30%)
leucine-rich repeat 113..136 CDD:275380 5/22 (23%)
LRR_8 135..195 CDD:290566 18/61 (30%)
LRR_4 135..175 CDD:289563 14/41 (34%)
leucine-rich repeat 137..160 CDD:275380 9/24 (38%)
leucine-rich repeat 161..184 CDD:275380 7/22 (32%)
leucine-rich repeat 185..209 CDD:275380 6/24 (25%)
leucine-rich repeat 210..231 CDD:275380 6/35 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.