DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment atk and CG4781

DIOPT Version :9

Sequence 1:NP_001262113.1 Gene:atk / 40266 FlyBaseID:FBgn0036995 Length:1535 Species:Drosophila melanogaster
Sequence 2:NP_611951.1 Gene:CG4781 / 37943 FlyBaseID:FBgn0035043 Length:469 Species:Drosophila melanogaster


Alignment Length:569 Identity:129/569 - (22%)
Similarity:195/569 - (34%) Gaps:176/569 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   432 LKGLDLAQNQFARVDSQLLAG-LPSLRRLDLSENGLI---ELAPNSFRHNPLLETLNISSNELTK 492
            ::||     .||.:.:||||. :.....:|..|....   |.:.||.|.   .|..|:|::... 
  Fly     7 IRGL-----TFALLLTQLLAAHVARAEVIDAEETDRFCYPESSKNSRRS---CECSNVSASPWG- 62

  Fly   493 IHSSTLIHLERLFEVDASYNQLK----SVIAGLPRIVERISLKGNQITSLPAAASKDLQLPNLRM 553
                     .|...:|.||...|    |::  ||..::.:.|..|.:.|:|...|..|...||| 
  Fly    63 ---------NRALRIDCSYKDYKVADLSLL--LPLYIDSLDLSWNALDSVPIFTSDSLHQLNLR- 115

  Fly   554 LDLSQNRIEQLPRHGFQGAMELRVLSLAQNELRQLKDTSFIGIQRLELLHLQENQLGEADERALL 618
                .|.|.||....|:....||.|.|..|.:.:|:..||.|:..|::|.|..|.|.........
  Fly   116 ----HNNISQLVSGNFKQLTSLRELYLGWNSIGKLESGSFDGLPHLQVLDLAHNNLHLLPGHLFA 176

  Fly   619 PLAELRNLNLQSNKLEAITDNFFSNNSRLEQLDLSRNLIRSISPTAFDTQRSLEYLDLSGNALLD 683
            ||..|..|::..|:      .|..:...|.              |.......|..|.|...:|.|
  Fly   177 PLLVLGTLDISWNR------RFNESGGDLY--------------TGLGVNWKLSTLRLDACSLND 221

  Fly   684 ISVGLGNLNNLRDIDLSYNQISRIQSDVIGGWRNVVEIRLSNNLIVELQQGTFRNLPK-LQYLDL 747
            :.:.:.  ..|:::.|..||:.||.:                            .||: |..||:
  Fly   222 LHLPVN--APLKELSLRRNQLKRIPT----------------------------QLPETLLRLDI 256

  Fly   748 SSNEIRNVEPGALKGLDELQEFVLADNKLVELKDHVFEELPSLLASHFQYNKLRYISPESFHNAN 812
            |.|.:..:.|.....|.::::..:             |::|.|         .|.:       ||
  Fly   257 SDNLLEELLPEDTANLTQVRQLFI-------------EDMPVL---------QRVV-------AN 292

  Fly   813 SLVFLNLSNNHFRNMENIGLRSMRNLEVLDLSTNGVKLVSTMPLKALNWLVELKMDNNQICRIQG 877
            ||       .|...:|.:..::.|.|..||....|.  :.|.|.|                    
  Fly   293 SL-------THVDVLETLSFQNSRQLSHLDAEAFGP--IMTTPTK-------------------- 328

  Fly   878 SPFETMPRLRVLSMRNNQLRSIKERTFRNVRGNIAILDVDGNPIDCNCEMQWLSVWLQETNFPYP 942
                 ...||.||.|...||:... |...:...:|.||::|.|:.|:||:.||.....:||    
  Fly   329 -----KRALRSLSFRGTMLRTFNS-TLAPIFTQLAELDLNGLPLQCDCELVWLKQLPVQTN---- 383

  Fly   943 GPKCQDGRLLRSARMERSLCVGADIYGNERTDGNQLPLLNEHGDVFQRD 991
                  ||..:.||:...|...|                  .||.|..|
  Fly   384 ------GRCYKPARIRGMLVTSA------------------RGDAFSCD 408

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
atkNP_001262113.1 leucine-rich repeat 69..89 CDD:275380
leucine-rich repeat 90..113 CDD:275380
leucine-rich repeat 115..138 CDD:275380
leucine-rich repeat 139..160 CDD:275380
leucine-rich repeat 161..184 CDD:275380
LRR_8 183..244 CDD:290566
leucine-rich repeat 185..209 CDD:275380
LRR_4 209..247 CDD:289563
leucine-rich repeat 210..233 CDD:275380
leucine-rich repeat 234..259 CDD:275380
LRR_RI 250..492 CDD:238064 17/63 (27%)
LRR_8 259..318 CDD:290566
leucine-rich repeat 260..283 CDD:275380
leucine-rich repeat 284..307 CDD:275380
leucine-rich repeat 308..359 CDD:275380
leucine-rich repeat 334..348 CDD:275378
LRR_8 358..418 CDD:290566
leucine-rich repeat 360..383 CDD:275380
leucine-rich repeat 384..407 CDD:275380
LRR_8 406..466 CDD:290566 10/34 (29%)
leucine-rich repeat 408..431 CDD:275380
leucine-rich repeat 432..455 CDD:275380 8/23 (35%)
LRR_RI 447..705 CDD:238064 66/265 (25%)
LRR_8 454..514 CDD:290566 13/62 (21%)
leucine-rich repeat 456..476 CDD:275380 5/22 (23%)
leucine-rich repeat 480..501 CDD:275380 3/20 (15%)
leucine-rich repeat 505..517 CDD:275378 4/15 (27%)
leucine-rich repeat 525..550 CDD:275380 6/24 (25%)
LRR_8 549..609 CDD:290566 21/59 (36%)
leucine-rich repeat 551..574 CDD:275380 7/22 (32%)
leucine-rich repeat 575..598 CDD:275380 9/22 (41%)
leucine-rich repeat 599..622 CDD:275380 7/22 (32%)
LRR_8 622..681 CDD:290566 9/58 (16%)
leucine-rich repeat 623..646 CDD:275380 4/22 (18%)
LRR_RI 647..896 CDD:238064 45/249 (18%)
leucine-rich repeat 647..670 CDD:275380 2/22 (9%)
leucine-rich repeat 671..693 CDD:275380 5/21 (24%)
leucine-rich repeat 694..717 CDD:275380 6/22 (27%)
LRR_8 716..776 CDD:290566 9/60 (15%)
leucine-rich repeat 718..741 CDD:275380 1/22 (5%)
leucine-rich repeat 742..763 CDD:275380 6/20 (30%)
LRR_8 765..824 CDD:290566 8/58 (14%)
leucine-rich repeat 766..789 CDD:275380 1/22 (5%)
leucine-rich repeat 790..813 CDD:275380 3/22 (14%)
leucine-rich repeat 814..835 CDD:275380 3/20 (15%)
leucine-rich repeat 838..861 CDD:275380 7/22 (32%)
LRR_8 862..921 CDD:290566 12/58 (21%)
leucine-rich repeat 862..885 CDD:275380 0/22 (0%)
leucine-rich repeat 886..906 CDD:275380 8/19 (42%)
TPKR_C2 919..>946 CDD:301599 8/26 (31%)
CG4781NP_611951.1 leucine-rich repeat 90..108 CDD:275380 5/17 (29%)
LRR_8 108..167 CDD:290566 22/63 (35%)
leucine-rich repeat 109..132 CDD:275380 9/27 (33%)
LRR_RI <121..>261 CDD:238064 43/189 (23%)
leucine-rich repeat 133..156 CDD:275380 9/22 (41%)
leucine-rich repeat 157..180 CDD:275380 7/22 (32%)
leucine-rich repeat 181..208 CDD:275380 6/46 (13%)
leucine-rich repeat 230..253 CDD:275380 9/50 (18%)
leucine-rich repeat 254..274 CDD:275380 6/19 (32%)
leucine-rich repeat 275..299 CDD:275380 9/59 (15%)
leucine-rich repeat 300..319 CDD:275380 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.