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Protein Alignment atk and LRRC32

DIOPT Version :9

Sequence 1:	NP_001262113.1	Gene:	atk / 40266	FlyBaseID:	FBgn0036995	Length:	1535	Species:	Drosophila melanogaster
Sequence 2:	NP_001122394.1	Gene:	LRRC32 / 2615	HGNCID:	4161	Length:	662	Species:	Homo sapiens

Alignment Length:	629	Identity:	171/629 - (27%)
Similarity:	257/629 - (40%)	Gaps:	140/629 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 PRLRYLDMSGNLLSELPYGALRGHGTLEQLHLNHNHLRLIERDALMAMPALRELRMRNNSLSSDL 422
            |....||:|||.|..:....|..:..|..|.|:.|.:..::..|..|:..|..|.:.:|.|:...
Human    49 PDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMAT 113

  Fly   423 PLP---FWNLPGLKGLDLAQNQ-FARVDSQLLAGLPSLRRLDLSENGLIELAPNSFRHNPLLETL 483
            .|.   ...||.:..|||:.|. ::.:..:||...|||..|.|:||.|..|..::||..|.||.|
Human   114 ALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQL 178

  Fly   484 NISSNELTKIHSSTLIHLERLFEVDASYNQLKSVIAGLPRIVERISLKGNQITSLPAAASKDLQL 548
            :        :||:.|:.:|     |.::.       ||||:. .::|..|.:|.:     .|..|
Human   179 D--------LHSNVLMDIE-----DGAFE-------GLPRLT-HLNLSRNSLTCI-----SDFSL 217

  Fly   549 PNLRMLDLSQNRIEQLPRHGFQGA------MELRVLSLAQNELRQLKDTSFIGIQRLELLHLQEN 607
            ..||:||||.|.||     .||.|      .:|..|.|.:|:|....|.:  .:.||..|:|..|
Human   218 QQLRVLDLSCNSIE-----AFQTASQPQAEFQLTWLDLRENKLLHFPDLA--ALPRLIYLNLSNN 275

  Fly   608 QL-----------------------------GEADERALLPLAELRNLNLQSNKLEAITDNFFSN 643
            .:                             |.|..|   ||::|.||:|..|::|.|.|:|..:
Human   276 LIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGR---PLSQLLNLDLSYNEIELIPDSFLEH 337

  Fly   644 NSRLEQLDLSRNLIRSISPTAFDTQRSLEYLDLSGNALLDISVGLGNLNNLRDIDLSYNQISRIQ 708
            .:.|..|:||||.:|:.......:...|..||||.|||..:.:|...|.:||
Human   338 LTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLR------------- 389

  Fly   709 SDVIGGWRNVVEIRLSNNLIVELQQGTFRNLPKLQYLDLSSNEIRNV----EPG-----ALKGLD 764
                       .:.|..|.:.:|...||.||..||.|:|..|.:...    |||     |..|:.
Human   390 -----------TLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGIT 443

  Fly   765 ELQEFVLADNKLVELKDHVFEELPSLLASHFQYNKLRYISPESFHNANSLVFLNLSNNHFRNMEN 829
            .|:...|.||::..|:...|...|                         |..|:||:|....:..
Human   444 SLRSLSLVDNEIELLRAGAFLHTP-------------------------LTELDLSSNPGLEVAT 483

  Fly   830 IGLRSMR-NLEVLDLSTNGVKLVSTMPLKALNWLVELKMDNNQICRIQGSPFETMP-RLRVLSMR 892
            ..|..:. :||||.|..||: :|..:.|.....|..|.:..|::..:   |..|.. .|.||.:|
Human   484 GALGGLEASLEVLALQGNGL-MVLQVDLPCFICLKRLNLAENRLSHL---PAWTQAVSLEVLDLR 544

  Fly   893 NNQLRSIKERTFRNVRGNIAILDVDGNPIDCNCEMQWLSVWLQE 936
            ||....:.......:..::..|.:.|||:.| |...||:..|.:
Human   545 NNSFSLLPGSAMGGLETSLRRLYLQGNPLSC-CGNGWLAAQLHQ 587

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.