Protein Alignment atk and lron-11

DIOPT Version :10

• Sequence 1: NP_649228.1
• Gene: atk / 40266
• FlyBaseID: FBgn0036995
• Length: 1535
• Species: Drosophila melanogaster
• Sequence 2: NP_491035.1
• Gene: lron-11 / 171837
• WormBaseID: WBGene00022129
• Length: 542
• Species: Caenorhabditis elegans
• Alignment Length: 464
• Identity: 125/464 - (26%)
• Similarity: 212/464 - (45%)
• Gaps: 80/464 - (17%)

  Fly   472 NSFRHNPLL-----ETLNISSNELTKIHSSTLIHLERLFEVDASYNQLKSVIAGLPRIVERISLK 531
            :|.|..|:|     ..|::|:|.::::.:..|          :.|..|           |::.|.
 Worm    35 SSLRSIPILLDPRTTVLDLSNNRISRLSADEL----------SLYPNL-----------EQLILH 78

  Fly   532 GNQITSLPAAASKDLQLPNLRMLDLSQNRIEQLPRHGFQGAMELRVLSLAQNELRQLKDTSFIGI 596
            .|.||.|.|....  .||:||:||||.|.:..||...|.....|:.|.::.|:: ||....|.|:
 Worm    79 NNSITHLSADVFS--TLPSLRVLDLSSNSLLSLPNEVFSKLKNLKTLIISSNDV-QLGPECFAGL 140

  Fly   597 QRLELLHLQENQLGEADERALLPLAELRNLNLQSNKLEAITDNFFSNNSRLEQLDLSRNLIRSIS 661
            .:|:.|.:.:|:|.......|.||:.||||:|.:|||.::..:..:|...||.|.|.:||:.|:.
 Worm   141 SQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKLLSMPASVMNNLGGLETLKLKQNLLSSLE 205

  Fly   662 PTAFDTQRSLEYLDLSGNALLDISVG-LGNLNNLRDIDLSYNQISRIQSDVIGGWR--NVVEIRL 723
            ...|.:|:.|::||:|.|.:.||..| |..|..|..::|:.||:.|:..:.   |.  .:..:.|
 Worm   206 TGMFLSQKELKHLDVSENLIGDIEEGALYGLEKLETLNLTNNQLVRLPGNT---WSLPALKTLDL 267

  Fly   724 SNNLIVELQQGTFRNLPKLQYLDLS-SNEIRNVEPGALKGLDELQEFVLADNKLVELKDHVFEEL 787
            |:||.|.|:..:|..||.||||::| |..::.::......|..|....::.:.|..:....|..:
 Worm   268 SSNLFVSLETASFDGLPALQYLNISHSRNLKTIQMATFVQLSSLHWLSISSSALTHIHPSAFNPI 332

  Fly   788 PSLLASHFQYNKLRYISPESFHNANSLVFLNLSNNHFRN----------MENIGLRSMRNLEVLD 842
            |.|.......|:|||::|      ..|.:.|:.|.|..|          :.|:..|.       |
 Worm   333 PPLSHLDLSNNELRYVAP------GMLQWPNIRNLHLANNDWHCSCDLRVSNLNPRD-------D 384

  Fly   843 LSTNGVKLVSTMPLKALNWLVELKMDNNQICRIQGS---PFETMPRLRVLSM-------RNNQLR 897
            ...:|.:.::..|:..|:           .|.|.|.   ||..:..:.:|::       :.::..
 Worm   385 AKCSGPENLAGAPINELS-----------SCSILGGLLIPFLLVLFILLLALVILALACKKSKPV 438

  Fly   898 SIKERTFRN 906
            |:|.|.|.|
 Worm   439 SLKNRAFYN 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atk	NP_649228.1	leucine-rich repeat	886..906	CDD:275380	5/26 (19%)
		PCC	891..>936	CDD:188093	5/23 (22%)
		leucine-rich repeat	69..89	CDD:275380
		leucine-rich repeat	90..113	CDD:275380
		LRR	93..530	CDD:443914	11/62 (18%)
		leucine-rich repeat	115..138	CDD:275380
		leucine-rich repeat	139..160	CDD:275380
		leucine-rich repeat	161..184	CDD:275380
		leucine-rich repeat	185..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..259	CDD:275380
		leucine-rich repeat	260..283	CDD:275380
		leucine-rich repeat	284..307	CDD:275380
		leucine-rich repeat	308..359	CDD:275380
		leucine-rich repeat	334..348	CDD:275378
		PLN00113	359..>824	CDD:215061	106/360 (29%)
		leucine-rich repeat	360..383	CDD:275380
		leucine-rich repeat	384..407	CDD:275380
		leucine-rich repeat	408..431	CDD:275380
		leucine-rich repeat	432..455	CDD:275380
		leucine-rich repeat	456..476	CDD:275380	1/3 (33%)
		leucine-rich repeat	480..501	CDD:275380	5/25 (20%)
		leucine-rich repeat	505..517	CDD:275378	2/11 (18%)
		leucine-rich repeat	525..550	CDD:275380	8/24 (33%)
		leucine-rich repeat	551..574	CDD:275380	10/22 (45%)
		leucine-rich repeat	575..598	CDD:275380	7/22 (32%)
		leucine-rich repeat	599..622	CDD:275380	7/22 (32%)
		leucine-rich repeat	623..646	CDD:275380	9/22 (41%)
		leucine-rich repeat	647..670	CDD:275380	9/22 (41%)
		leucine-rich repeat	671..693	CDD:275380	10/22 (45%)
		leucine-rich repeat	694..717	CDD:275380	6/24 (25%)
		leucine-rich repeat	718..741	CDD:275380	8/22 (36%)
		leucine-rich repeat	742..763	CDD:275380	6/21 (29%)
		leucine-rich repeat	766..789	CDD:275380	3/22 (14%)
		leucine-rich repeat	790..813	CDD:275380	6/22 (27%)
		leucine-rich repeat	814..835	CDD:275380	7/30 (23%)
		leucine-rich repeat	838..861	CDD:275380	4/22 (18%)
		leucine-rich repeat	862..885	CDD:275380	5/25 (20%)
lron-11	NP_491035.1	LRR	33..368	CDD:443914	108/365 (30%)
		leucine-rich repeat	48..71	CDD:275380	5/32 (16%)
		leucine-rich repeat	72..95	CDD:275380	9/35 (26%)
		leucine-rich repeat	96..119	CDD:275380	10/22 (45%)
		leucine-rich repeat	120..142	CDD:275380	7/22 (32%)
		leucine-rich repeat	143..166	CDD:275380	7/22 (32%)
		leucine-rich repeat	167..190	CDD:275380	9/22 (41%)
		leucine-rich repeat	191..214	CDD:275380	9/22 (41%)
		leucine-rich repeat	215..238	CDD:275380	10/22 (45%)
		leucine-rich repeat	239..261	CDD:275380	6/24 (25%)
		leucine-rich repeat	262..283	CDD:275380	7/20 (35%)
		leucine-rich repeat	286..310	CDD:275380	7/23 (30%)
		leucine-rich repeat	311..334	CDD:275380	3/22 (14%)
		leucine-rich repeat	335..357	CDD:275380	7/27 (26%)