DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Psn and PS1

DIOPT Version :9

Sequence 1:	NP_001262111.1	Gene:	Psn / 40260	FlyBaseID:	FBgn0284421	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_172346.1	Gene:	PS1 / 837391	AraportID:	AT1G08700	Length:	453	Species:	Arabidopsis thaliana

Alignment Length:	460	Identity:	142/460 - (30%)
Similarity:	237/460 - (51%)	Gaps:	61/460 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 VIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPS--VKFWSALANSLILMSVVV 166
            :|.:..|||:||.:||....|:|..:...:.......:.::|..|  ||...:|||:::.:.::.
plant    13 IIGVMAPVSICMFLVVLLTYSLSVTSDPQIRSAANLIYIENPSDSTTVKLEGSLANAIVFVVLIA 77

  Fly   167 VMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVG 231
            .:||:|::|:.......:..::..|:|.:|..........:::.::||:|..|..::::||.::|
plant    78 AVTFILVLLFYYNFTNFLKHYMRFSAFFVLGTMGGAIFLSIIQHFSIPVDSITCFILLFNFTILG 142

  Fly   232 MMSIHWQG-PLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVE 295
            .:|:...| |:.|:|.|::.:..::|..|.| |||||.|.:|.|::::||:|||:|.|||::|||
plant   143 TLSVFAGGIPIVLRQCYMVVMGIVVAAWFTK-LPEWTTWFILVALALYDLVAVLAPGGPLKLLVE 206

  Fly   296 TAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAAS 360
            .|..|:|:: ||::|               :::.|.||.....|..::.||........::.:..
plant   207 LASSRDEEL-PAMVY---------------EARPTVSSGNQRRNRGSSLRALVGGGGVSDSGSVE 255

  Fly   361 GQRTGNSHPRQNQRD-----DGSVLATEGMPLVTFKSNLRGNAEAAGFTQEWSANLSERVARRQI 420
            .|...|....|..|:     |.:.:|...:..|   .:..||....|..:      |..|.....
plant   256 LQAVRNHDVNQLGRENSHNMDYNAIAVRDIDNV---DDGIGNGSRGGLER------SPLVGSPSA 311

  Fly   421 EVQSTQSGNAQRSN-EYRTVTAPDQNHP--------DGQEE---------------RGIKLGLGD 461
            ...||..|.  |.| |.|.....::..|        |.:||               |||||||||
plant   312 SEHSTSVGT--RGNMEDRESVMDEEMSPLVELMGWGDNREEARGLEESDNVVDISNRGIKLGLGD 374

  Fly   462 FIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAV 526
            |||||||||:|:.| |..|..||::||:.||..||:||:::.:|||||||||..|::|.|.|..:
plant   375 FIFYSVLVGRAAMY-DLMTVYACYLAIISGLGCTLILLSVYNRALPALPISIMLGVVFYFLTRLL 438

  Fly   527 VKPFM 531
            ::||:
plant   439 MEPFV 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Psn	NP_001262111.1	Presenilin	98..531	CDD:279427	141/458 (31%)
PS1	NP_172346.1	Presenilin	10..443	CDD:395857	141/458 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	203	1.000	Domainoid score	I843
eggNOG	1	0.900	-	-		E1_KOG2736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I1299
OMA	1	1.010	-	-		QHG54370
OrthoDB	1	1.010	-	-		D797738at2759
OrthoFinder	1	1.000	-	-		FOG0002393
OrthoInspector	1	1.000	-	-		otm2476
orthoMCL	1	0.900	-	-		OOG6_101989
Panther	1	1.100	-	-	O	PTHR10202
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1815
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840