Protein Alignment Psn and hop-1

DIOPT Version :9

• Sequence 1: NP_001262111.1
• Gene: Psn / 40260
• FlyBaseID: FBgn0284421
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_491328.1
• Gene: hop-1 / 172017
• WormBaseID: WBGene00001985
• Length: 358
• Species: Caenorhabditis elegans
• Alignment Length: 444
• Identity: 118/444 - (26%)
• Similarity: 201/444 - (45%)
• Gaps: 95/444 - (21%)

  Fly    99 YGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMS 163
            |..:.:..:..||::|||.|...:............::|..||......|...      :|.|:.
 Worm     8 YSGKTITGVLYPVAICMLFVAINVKLSQPEQQEQSKVVYGLFHSYDTADSGTI------TLYLIG 66

  Fly   164 VVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFG 228
            .:::.|.|.:..|:.:.|:.|..:::.:|..:|.:::..:.:.:..|.:||:..||...::..||
 Worm    67 FLILTTSLGVFCYQMKFYKAIKVYVLANSIGILLVYSVFHFQRIAEAQSIPVSVPTFFFLILQFG 131

  Fly   229 VVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRIL 293
            .:|:..:||:...||.|.|||.:|.|.|:..:..||:||.|..|.|||.||::|||:|.|||::|
 Worm   132 GLGITCLHWKSHRRLHQFYLIMLAGLTAIFILNILPDWTVWMALTAISFWDIVAVLTPCGPLKML 196

  Fly   294 VETAQERNEQIFPALIYSSTVVYALVNTV-TPQQSQATASSSPSSSNSTTTTRATQNSLASPEAA 357
            ||||..|.:..|||::|:|:   :.||.| :|..:::.::.....:||:::.....:||..|...
 Worm   197 VETANRRGDDKFPAILYNSS---SYVNEVDSPDTTRSNSTPLTEFNNSSSSRLLESDSLLRPPVI 258

  Fly   358 AASGQRTGNSHPRQNQRDDGSVLATEGMPLVTFKSNLRGNAEAAGFTQEWSANLSERVARRQIEV 422
                       |||                                            .|...||
 Worm   259 -----------PRQ--------------------------------------------IREVREV 268

  Fly   423 QSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVA 487
            :.|                             |:||:|||:|||:::|.........|.:||||:
 Worm   269 EGT-----------------------------IRLGMGDFVFYSLMLGNTVQTCPLPTVVACFVS 304

  Fly   488 ILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI 541
            .|:||.:||.::.:.:.||||||..:....||.|::...:.|| .||...|:.:
 Worm   305 NLVGLTITLPIVTLSQTALPALPFPLAIAAIFYFSSHIALTPF-TDLCTSQLIL 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psn	NP_001262111.1	Presenilin	98..531	CDD:279427	114/432 (26%)
hop-1	NP_491328.1	Peptidase_A22B	8..348	CDD:294809	115/433 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3257
OMA	1	1.010	-	-		QHG54370
OrthoDB	1	1.010	-	-		D357270at33208
OrthoFinder	1	1.000	-	-		FOG0002393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101989
Panther	1	1.100	-	-	O	PTHR10202
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.740