Protein Alignment Psn and Psn

DIOPT Version :10

• Sequence 1: NP_524184.1
• Gene: Psn / 40260
• FlyBaseID: FBgn0284421
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_061505643.1
• Gene: Psn / 1273006
• VectorBaseID: AGAMI1_000986
• Length: 540
• Species: Anopheles gambiae
• Alignment Length: 564
• Identity: 323/564 - (57%)
• Similarity: 389/564 - (68%)
• Gaps: 75/564 - (13%)

  Fly    15 ASEDDANVGSQIGAAERLERPP--RRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLT 77
            |:..||:.|.  |:.:|.::.|  .......:||:::         ::|.|.:|: ..||
Mosquito    15 ATAQDASDGR--GSRKRWQKMPADASSSPHPSYGTTD---------SIPQVTIRD-TSSR----- 62

  Fly    78 GGGGGSGGPPTNE---------------MEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISF 127
            |..|.|.|.|:..               :.||:||||||||||||||||:|||:||||||:||:|
Mosquito    63 GRAGPSRGSPSGNSSRQRQQQQQEQEQALNEEEGLKYGAQHVIKLFVPVTLCMMVVVATISSINF 127

  Fly   128 YNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSS 192
            |...||||:||||||.:.:...|.|:|||||||||:|:|:||.|||||||.|||::|||||||||
Mosquito   128 YTIKDVYLVYTPFHELTDDTGTKIWNALANSLILMTVIVIMTILLIVLYKHRCYKVIHGWLILSS 192

  Fly   193 FMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMAL 257
            .:|||:|:.|||.|:|||||:|||:.||.|::||||||||:||||||||||||||||||||||||
Mosquito   193 LLLLFLFSGLYLFEILRAYNVPMDWFTAGLLVWNFGVVGMISIHWQGPLRLQQGYLIFVAALMAL 257

  Fly   258 VFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTV 322
            ||||||||||.|||||.||||||||||:|:||||||||||||||||||||||||||::|:.:.|.
Mosquito   258 VFIKYLPEWTTWAVLAVISIWDLIAVLTPKGPLRILVETAQERNEQIFPALIYSSTIMYSYLGTH 322

  Fly   323 T------PQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSH-PRQNQRDDGSVL 380
            |      |...:.|..:.|.|              |...:..|.|....|:| |.|.    |:.:
Mosquito   323 TDPDRAAPLSGERTIGTGPGS--------------AGGGSRQAGGYGAVNNHGPTQT----GATV 369

  Fly   381 ATEGMPLVTFKSNLRGNA---EAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTA- 441
              |||.||...::...:.   :.|||||:|:|..::||.|||||||:..:.|..|. |||||||
Mosquito   370 --EGMRLVAIPNDRTHDLPRDQTAGFTQDWAATANQRVTRRQIEVQANIANNPSRP-EYRTVTAE 431

  Fly   442 -------PDQNHP--DGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLL 497
                   |.....  |..||||||||||||||||||||||||||||.||||||||||:|||||||
Mosquito   432 ATRAGQDPQLGGALYDQAEERGIKLGLGDFIFYSVLVGKASSYGDWNTTIACFVAILVGLCLTLL 496

  Fly   498 LLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI 541
            ||||:|||||||||||.|||||||.||.:||||.|.|:.:||||
Mosquito   497 LLAIFRKALPALPISIFFGLIFCFVTSVIVKPFTEALTLEQVFI 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psn	NP_524184.1	Presenilin	98..531	CDD:460052	293/452 (65%)
Psn	XP_061505643.1	None