DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5274 and c7orf26

DIOPT Version :9

Sequence 1:	NP_649222.1	Gene:	CG5274 / 40257	FlyBaseID:	FBgn0036987	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001016231.1	Gene:	c7orf26 / 548985	XenbaseID:	XB-GENE-5734232	Length:	450	Species:	Xenopus tropicalis

Alignment Length:	403	Identity:	119/403 - (29%)
Similarity:	188/403 - (46%)	Gaps:	70/403 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DSNKLLLRKGDMKLDNYPTCAVEALTRLETLIASRNKQNMV-------MQIISEFIFLERTPKDG 63
            |....|||:..:      :.|.|.|..|:...:|:.:...|       ::::.||||  :.|||
Frog     3 DIRHSLLRRDTL------SAAKEVLYHLDIYFSSQLQNAPVPLVEKGPIELLEEFIF--QVPKD- 58

  Fly    64 DVRKSQALPISQMNLFQEFQLIIALIEYFSRPGRDATRNAIFLSLF---GSHLTPQRSKLLSRLI 125
              |.|.....|.|   ||.||:..|..||....::|.|..||.|||   |:....||..||.:|.
Frog    59 --RGSHTKRFSAM---QELQLLEILCNYFQEQNKEAVRQVIFSSLFSPQGNKADDQRMALLGKLT 118

  Fly   126 STAVSGSVAPLLSSAGTWMQQVGCKTP--LSLEVAQNIVSDFISYSRKTPEQLKQLPMVGPHFAA 188
            |.:|:....|:|..|.:|:|    :||  ..:.:|:.:|.|:......:.:.|||:..|.|.|..
Frog   119 SMSVAVCRVPVLECAASWLQ----RTPAVYCVRLAKALVDDYCGLVPGSVQTLKQIISVSPRFCC 179

  Fly   189 NFMVAVADLYLNEQRSPTLNPPPDALLDTITEWMMENPTLCQAS--QQPLV--LPAGAIAMPFTT 249
            .|:.|||.||  :..|..|.||.: ||:.|..|:.::|.|...:  ..|:.  :|.|.:..   :
Frog   180 QFITAVAALY--DMSSEELLPPHN-LLEMIVSWIFDDPMLILITFLNTPITANVPLGFLDF---S 238

  Fly   250 PLAGLLRWVVLAPL--------------VSNRSAYSNLHLSLLRALQQLVSS-------GESTAL 293
            ||.||:||.|.|||              |.::..||.||||:|:.|..|.:.       |.....
Frog   239 PLMGLVRWCVTAPLAYRRKQKAAGGQLPVESQGLYSKLHLSMLQGLMVLQTHLTEKNLYGRLGLF 303

  Fly   294 PSQDLMQIVKSLQSYCARLAESKTDPQADAAYQKCMERFAQAVQIALSSN---CITNQIQLLCLL 355
            ....|:.:|:.|...|..|.....:.:.:.|    ::|.|||:|:::::.   |..:.::.||
Frog   304 HFDQLVPLVEELGQLCDELNPLNAEQEMELA----LDRLAQALQVSMATGALLCARDDLRTLC-- 362

  Fly   356 ESLPPHKLMKIVI 368
            ..||.:.||::||
Frog   363 ARLPHNNLMQLVI 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5274	NP_649222.1	DUF4507	14..360	CDD:291625	110/385 (29%)
c7orf26	NP_001016231.1	DUF4507	2..367	CDD:405629	114/393 (29%)
c7orf26	NP_001016231.1	PHA03247	<378..447	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I5696
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H11445
Inparanoid	1	1.050	126	1.000	Inparanoid score	I4549
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1387798at2759
OrthoFinder	1	1.000	-	-		FOG0007054
OrthoInspector	1	1.000	-	-		oto105385
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5565
SonicParanoid	1	1.000	-	-		X5922
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090