DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5282 and Dpep3

DIOPT Version :9

Sequence 1:	NP_649221.1	Gene:	CG5282 / 40256	FlyBaseID:	FBgn0036986	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_082236.1	Gene:	Dpep3 / 71854	MGIID:	1919104	Length:	493	Species:	Mus musculus

Alignment Length:	354	Identity:	109/354 - (30%)
Similarity:	190/354 - (53%)	Gaps:	57/354 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 LLEARLAFIRRLLTESPLIEGSWKPP----------------STMSLNSSNLFEVRQNHIGAVLW 160
            |.|..||.:|    :.||::|....|                ...:...:||..:|...:||..|
Mouse    77 LREQALALMR----DFPLVDGHNDLPLLLRELFQNQLQDVNLRNFTRGQTNLDRLRDGLVGAQFW 137

  Fly   161 PIAVPCGAQYLDAVQLTLEGIDRAKRITAATDSMHIVESADEMEQTHIRGEVAVLMGISGGHALG 225
            ...:||..|..|||:|.||.||..:|:.:|...:.:|.|||.:..|.   ::|.|:|:.|||:|.
Mouse   138 SAYIPCQTQDRDAVRLALEQIDLIRRMCSAYPELELVTSADGLNNTQ---KLACLIGVEGGHSLD 199

  Fly   226 TSTAVLRSIYLLGARFVSITSLECTTPWAAAAIRRPDYLVEENVTNSFNEFGQTMLFEMNRLGML 290
            ||.|||||.|.||.|::::| ..|:||||.:|.:...:.. .|: :....||:.::.|||||||:
Mouse   200 TSLAVLRSFYELGVRYLTLT-FTCSTPWAESATKFRHHFY-TNI-SGLTSFGEKVVEEMNRLGMM 261

  Fly   291 VEISMLSEAAMLAVLKTAKAPVLLTNATPLSMCNSSNIASIPDHVLSLLPENGGVILLNLERCGD 355
            :::|..|:..:...|:.::|||:.:::...|:|:  |:.:|||.:|.||.:|||::::.|
Mouse   262 IDLSHASDTLVKQTLEVSQAPVIFSHSAARSVCD--NLLNIPDDILQLLKKNGGIVMVTL----- 319

  Fly   356 RTLGVREAITAIN---------YVRKVAGVDHIGLGGA-------PK------SYALLLAELARD 398
             ::||.:.....|         ::|.|.|.:.||:||:       |:      :|.:|:.||. .
Mouse   320 -SMGVLQCSLFANVSTVADHFDHIRTVIGSEFIGIGGSYDGSGRFPQGLEDVSTYPVLIEELL-S 382

  Fly   399 RVWGNAAIKKLVGGNVMRILREIETLKNR 427
            |.|....::.::.||::|:.|::|.::.:
Mouse   383 RGWDERELQGVLRGNLLRVFRQVEQVREK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5282	NP_649221.1	Peptidase_M19	123..420	CDD:395996	102/334 (31%)
Dpep3	NP_082236.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	41..74
Dpep3	NP_082236.1	Peptidase_M19	83..404	CDD:279569	104/339 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2355
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1272387at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880