DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5282 and SPAC3A11.10c

DIOPT Version :9

Sequence 1:	NP_649221.1	Gene:	CG5282 / 40256	FlyBaseID:	FBgn0036986	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_594193.1	Gene:	SPAC3A11.10c / 2543080	PomBaseID:	SPAC3A11.10c	Length:	409	Species:	Schizosaccharomyces pombe

Alignment Length:	436	Identity:	109/436 - (25%)
Similarity:	184/436 - (42%)	Gaps:	103/436 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 SESSAERP-----ERSRGRKI----LLGVGVVLVCIAMAG-----GIPLALQLRSSSLLEARLAF 119
            |:|..|.|     ::.|.|:|    ||...::|..:...|     ..|           |.:..|
pombe     3 SDSKLELPLPVNQQKPRRRRILKVHLLIAALILSAVGYLGKGKWIWTP-----------ERKAHF 56

  Fly   120 IRRLLTESPLIEGSWKPPSTMSLNSSN---------------LFEVRQNHIGAVLWPIAVPCGA- 168
            :   ||..|||:|....|..:..|..|               :|.:||.|:|...|.:.|.|.:
pombe    57 V---LTHFPLIDGHNDLPIYLRENYDNRLLNISLEHLPGQTDIFRLRQGHVGGQFWSVFVECPSL 118

  Fly   169 ------------QYLDAVQLTLEGIDRAKRITA-ATDSMHIVESADEMEQTHIRGEVAVLMGISG 220
                        :| :||..||:.||..||:.. ...:..:.:.:.:::...:|..::.:|||.|
pombe   119 DSNSSLSWNRTGEY-EAVTQTLQQIDVVKRMALYYPKTFSLTDHSGKVKFDFLRNHISSMMGIEG 182

  Fly   221 GHALGTSTAVLRSIYLLGARFVSITSLECTTPWAAAAIRRPDYLVEENVTN-SFNEFGQTMLFEM 284
            .|.:..|.::||..|.||.|:.::.. .|...:|.||       |:...|| ..:..|:.::.||
pombe   183 LHQIAGSPSILRQFYDLGVRYATLAH-NCDNVFADAA-------VDGKRTNKGLSPAGRDIVREM 239

  Fly   285 NRLGMLVEISMLSEAAMLAVLKTAKAPVLLTNATPLSMCNSSNIASIPDHVLSLLPENGGVILLN 349
            |||||:|::|..:...|...|..:.||...::::...:.:...  ::||.||..:.|..||:::|
pombe   240 NRLGMIVDLSHTTPETMHQALDVSVAPAFFSHSSAKGVYDHPR--NVPDDVLIRVKETDGVVMVN 302

  Fly   350 L------ERCGDRTLGVREAITAINYVRKVAGVD----HIGLGG-------APK------SYALL 391
            .      ....:.|:.     |.:.::..:|.|.    ||||||       .||      .|..|
pombe   303 FYPAFISPHPENATID-----TVVEHIMHIANVTGSYRHIGLGGDFDGIDMVPKGLEDVSKYPDL 362

  Fly   392 LAELARDRVWGNAAIKKLVGGNVMRILREIETLKNRL---PLYEEW 434
            ..:|| :|......:..:.|.||:|:.:..|.|.:.:   ||  ||
pombe   363 FVKLA-ERGLSITELADIAGRNVLRVWKTTEDLGHSIHEPPL--EW 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5282	NP_649221.1	Peptidase_M19	123..420	CDD:395996	89/349 (26%)
SPAC3A11.10c	NP_594193.1	Peptidase_M19	57..389	CDD:279569	89/351 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2355
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870