DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zye and F07H5.8

DIOPT Version :9

Sequence 1:	NP_649220.1	Gene:	zye / 40255	FlyBaseID:	FBgn0036985	Length:	2284	Species:	Drosophila melanogaster
Sequence 2:	NP_495874.3	Gene:	F07H5.8 / 174407	WormBaseID:	WBGene00008559	Length:	835	Species:	Caenorhabditis elegans

Alignment Length:	1076	Identity:	257/1076 - (23%)
Similarity:	341/1076 - (31%)	Gaps:	398/1076 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   556 SKPNCYP-GSTDTRC-----PQAPGPRCYPGSPDPSCQPPTRITQKPPTSPQPKCYPGSSDPECL 614
            ||.|||| ||...||     ||:.|..|...:....|||.   .||   |....|...|..|:.|
Worm    40 SKCNCYPIGSGMQRCKCSNEPQSSGCSCANKAQTSVCQPS---CQK---SCVDSCVRNSHQPQLL 98

  Fly   615 NCYPGSPDPRCPKVPTTKKAGCYEGSDDPRCQPATYLPPSTRRPP--------TIAPR-PRCYLG 670
             |     |..|..  |..||          |.|:|....|:..||        |.|.: |:....
Worm    99 -C-----DKTCQF--TCNKA----------CTPSTSTSSSSNFPPIKVVVNQQTKASQCPQACAQ 145

  Fly   671 STDPSCPQQ-------------TQPT-------------TRTPITTIKPRCFPGSNDPECQPATT 709
            |...||..|             .|||             .||..||:.|               :
Worm   146 SCANSCTAQPNKSYCIDMCIKSCQPTCVQAAVSINVKEFMRTSTTTLAP---------------S 195

  Fly   710 RRPLTTSKPNCYPGSTDRRC-----PQEPVTTSRP---RCYPGSSDPECQPATLVPPTTVRTTIT 766
            |..::..:|.|     |.:|     ..|.:....|   :| |....|.|.|..:   .:|..:|.
Worm   196 RSCVSACQPTC-----DAQCINVMKRYEVIIQKMPLAQKC-PSQCQPTCSPQCI---QSVTVSIQ 251

  Fly   767 TSRQRCYPGSSDPSCQPPTTRKPITTPKPNCYPGSTDSRCPQTPRTTQQPRCYPGSTDPDCQP-- 829
            |:.|             |||...|...:|.|.|     :|.|...||:  .|.| :..|.|||
Worm   252 TTAQ-------------PTTASCIPACQPACTP-----QCVQAVTTTE--TCIP-ACQPACQPQC 295

  Fly   830 ---ATYLPPTTARTTITTAKPR-CYPGSSDPYCQPPTTKKPNC---YPGSTDSRCPQKPPITPKP 887
               ...:...|::.|..|..|. |.|.     |||..  :|.|   |..|..|.....||:|.
Worm   296 VERQLQIQIVTSQATQATRAPETCIPA-----CQPAC--QPQCVYQYLSSGSSGISTVPPVTK-- 351

  Fly   888 KCYPGSTDLECLNCYPGSPDPRCPKVPTTKKAGCFDGSDDPKCQPATYLPPSTKRTPTIAPKPRC 952
                     .|::.                            ||||                  |
Worm   352 ---------VCISI----------------------------CQPA------------------C 361

  Fly   953 YPGSKDPGCPQI--TTRAP---TSTSRPRCYPGSTDPECHPTTSSPAITRIPVTTRIPLTTAKPR 1012
                 ||||..|  ||.||   .|..:|.|.|..||               ..||.|.|
Worm   362 -----DPGCVAIYTTTPAPLHCVSQCQPACLPSCTD---------------TFTTTISL------ 400

  Fly  1013 CYPGSQEPGCQPATRPPITTSKPRCYPGSLDPECQPSTYLPPTPVRTTVPTIPTTRIPVTTSKPN 1077
              |....|.||||       .:.:|....:..:.:.|...|        ..:....||.::..|.
Worm   401 --PKQCVPECQPA-------CETKCIVAQIVLKIKNSYQQP--------QQLSQQYIPQSSCVPQ 448

  Fly  1078 CYPGSTDRRCPKEPVTTPKPRCYPGSPNPECQ-KATYSPPTTRTPVTTSKPNCYPGSTDSRCPQK 1141
            |.|.     |.:|        |....||...| ......|:|    :||.|.|.
Worm   449 CQPA-----CTQE--------CVAAQPNFSVQINMIDETPST----STSSPQCI----------- 485

  Fly  1142 PPTTLKPKCSPGSSDPECLNCYPGSPDPRCPKVPTTKKSGCFDGSQDPRCQPATYLPPSSRRPPT 1206
                  |:|.| |.|.:|:..|         |:...:.:......:...|.||
Worm   486 ------PQCQP-SCDQQCIQTY---------KIQVQQMNSQQKQQRQYNCVPA------------ 522

  Fly  1207 TAPKPRCHPGSTDPSCPQPTQPITTRLPITTQKARCYPGSTAPE-CQPATTP------TPTSTRP 1264
                  |.| :.:.||.|....:|    |....::...|::.|. ||||..|      |..:|.|
Worm   523 ------CQP-TCEQSCIQSQYQVT----IQQSYSKGNQGNSCPSACQPACEPLCVQQITVQTTVP 576

  Fly  1265 ITTITTSKPNCYPGSTDRRCPQ--------IPVTTTKPRCYP---GSTDPQCQPATY-LPPTTVT 1317
            ||  .|..|.|.|..| :.|.|        ||:||..|.|.|   .:.||||...|. ||..|..
Worm   577 IT--KTCVPQCQPACT-QECVQQATTYTISIPMTTAAPSCAPQCQPACDPQCISFTLKLPVMTTP 638

  Fly  1318 TVRPRCYPGSNDPGCQP-------------PQTTKTPITTSKPVCYLGSTDSRCRQNPSTTQKPK 1369
            ...|.|.| ...|.|||             .|::|......:|||     ||:|.||    .:.:
Worm   639 PPTPSCQP-QCQPACQPSCMETYTFTIPMNDQSSKQCAPACQPVC-----DSKCIQN----YQFE 693

  Fly  1370 CSVGSTDPECQPA-TYLPPTTVSPTIPTTKPRCYPGSTDTSCQP------KTYSPPTSRPLITTS 1427
            ..:...|..|.|| |....|:.......:.|:|....|| ||:.      |..:.||.:..|...
Worm   694 IVIPQADNNCMPACTQSCQTSCVQQNSQSVPQCSTACTD-SCRSSCVEIVKESAEPTFKLEIVLK 757

  Fly  1428 KPRCYPGSPDPECQPATYLPPTTRRTTIPVTKPRCYPGSSDPECQPETYSPPTTRPPVTTSKPNC 1492
            ||                     ...|: ...|:|.....| :|:.:          :.|....|
Worm   758 KP---------------------MEETV-TCAPQCANQCVD-QCKTQ----------LLTQIEFC 789

  Fly  1493 YPGSTDSRCPQKPPTTLQPKCYPGSSDPECLNCYPG 1528
            .| :..:.|.|..|..::|....||   :| ||..|
Worm   790 LP-ACQNACQQNCPLQVEPCAMSGS---QC-NCSTG 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
zye	NP_649220.1	ZP	61..313	CDD:214579
F07H5.8	NP_495874.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000