DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and TAT2

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_014622.1	Gene:	TAT2 / 854139	SGDID:	S000005380	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	556	Identity:	111/556 - (19%)
Similarity:	214/556 - (38%)	Gaps:	154/556 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGP-GIILSFILAG--FISMLAAL------- 89
            |.|.|....:.::.||..:|.|::|.:|....| .|| |:::.:.:||  .|..:..|
Yeast    78 LKRTLKPRHLIMIAIGGSIGTGLFVGSGKAIAE-GGPLGVVIGWAIAGSQIIGTIHGLGEITVRF 141

  Fly    90 ----CYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLE-HMLGAASVARAWSGYVDSMLGG 149
                .:|.:|||......::|.:.|       :|:.|..:|. .::.||...:.|:..:|.::
Yeast   142 PVVGAFANYGTRFLDPSISFVVSTI-------YVLQWFFVLPLEIIAAAMTVQYWNSSIDPVI-- 197

  Fly   150 WIGNTTLELTGGIHEPGLAQYPDVLAFLVCIVYAAALA-------GGVKATAVFNSL--LTLVNI 205
            |                           |.|.||..::       |..:|...|:::  :|:...
Yeast   198 W---------------------------VAIFYAVIVSINLFGVRGFGEAEFAFSTIKAITVCGF 235

  Fly   206 AVMVLVISVG----FWYADGKNWSEAEGGFLPYGVGGVIAGAATCFYAFVGFD-SIATSGEEAKN 265
            .::.:|:..|    ..:...|.|.:.  |.|..|..||::......|:..|.: :...|||  .:
Yeast   236 IILCVVLICGGGPDHEFIGAKYWHDP--GCLANGFPGVLSVLVVASYSLGGIEMTCLASGE--TD 296

  Fly   266 PSVSIPVA------TVISLFVVT---VGYILV-------------SAALTLMIPISEINPAASLP 308
            |. .:|.|      .::..|:::   ||:::.             ::...:.|.:..|....|:.
Yeast   297 PK-GLPSAIKQVFWRILFFFLISLTLVGFLVPYTNQNLLGGSSVDNSPFVIAIKLHHIKALPSIV 360

  Fly   309 EAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNL 373
            .|...::      ::|:|..|         :||..|.:.:||..||:...||.|:...: ||:.:
Yeast   361 NAVILIS------VLSVGNSC---------IFASSRTLCSMAHQGLIPWWFGYIDRAGR-PLVGI 409

  Fly   374 VVSG--------VMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPA 430
            :.:.        |.|..::.||:.  |:....:.|.:.:..::.|.|  |:|
Yeast   410 MANSLFGLLAFLVKSGSMSEVFNW--LMAIAGLATCIVWLSINLSHI--RFR------------- 457

  Fly   431 VAGSPDDDDDDDEDVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGRFEPG--------- 486
            :|........|:.:..|...: ..|..|.:|..::   |.|||.|....:|.:..|
Yeast   458 LAMKAQGKSLDELEFVSAVGI-WGSAYSALINCLI---LIAQFYCSLWPIGGWTSGKERAKIFFQ 518

  Fly   487 SVVSVAVMLFIFLSFAICVELKVSWTQLYTGTWWAL 522
            :.:...:|||||:...|       :.:..||.||.:
Yeast   519 NYLCALIMLFIFIVHKI-------YYKCQTGKWWGV 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	111/556 (20%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
TAT2	NP_014622.1	LysP	52..591	CDD:223903	111/556 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I2106
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1545
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960