DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and TAT1

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_009625.1	Gene:	TAT1 / 852361	SGDID:	S000000273	Length:	619	Species:	Saccharomyces cerevisiae

Alignment Length:	465	Identity:	93/465 - (20%)
Similarity:	182/465 - (39%)	Gaps:	93/465 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RRAILRHILSGICTKM--NRTKSVPTD---VMETP----LNRCLNTFDIALLGIGHMVGAGIYVL 60
            ||...:.||...|.:.  :..:.:|.|   .:|:.    |.:.:.:..:.::.:|..:|.|:.|.
Yeast    51 RRTDSKSILQRKCKEFFDSFKRQLPPDRNSELESQEKNNLTKSIKSRHLVMISLGTGIGTGLLVG 115

  Fly    61 TGTVAKEMAGP-GIILSFILAG---FISMLAA----LCYAEFGTRVPKAGSAYVYTYISMGEFWA 117
            .|.|. ..||| |::|.:.:|.   :..:.||    ||||.......:..|..|...:.......
Yeast   116 NGQVL-GTAGPAGLVLGYGIASIMLYCIIQAAGELGLCYAGLTGNYTRYPSILVDPSLGFAVSVV 179

  Fly   118 FVIGW-NILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAFLVCIV 181
            :.|.| .:|...::.||...:.|:..          |..:             :..|:...|.|:
Yeast   180 YTIQWLTVLPLQLVTAAMTVKYWTSV----------NADI-------------FVAVVFVFVIII 221

  Fly   182 YAAALAGGVKATAVFNS--LLTLVNIAVMVLVISVG-----------FWYADGKNWSEAEGGFLP 233
            ......|..:|..:|||  :|.::...::.::|:.|           :|:..|           |
Yeast   222 NLFGSRGYAEAEFIFNSCKILMVIGFVILAIIINCGGAGDRRYIGAEYWHNPG-----------P 275

  Fly   234 YGVGGVIAGAATCF----YAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTL 294
            :..|  ..|..|.|    :::.|.:.:..|..|.:||:.|||.|....::.:.:.|:|.:..:..
Yeast   276 FAHG--FKGVCTVFCYAAFSYGGIEVLLLSAAEQENPTKSIPNACKKVVYRILLIYMLTTILVCF 338

  Fly   295 MIPI----------SEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAM 349
            ::|.          |..:.|:....|.....:....:.|:...|..:.:....||::.||.:.::
Yeast   339 LVPYNSDELLGSSDSSGSHASPFVIAVASHGVKVVPHFINAVILISVISVANSSLYSGPRLLLSL 403

  Fly   350 ASDGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFD-------LAKLVEFMSIGTLLAYTIV 407
            |..|:|..|...::...: |||...|| ::..|:..|..       ...|:...|:..|..:  :
Yeast   404 AEQGVLPKCLAYVDRNGR-PLLCFFVS-LVFGCIGFVATSDAEEQVFTWLLAISSLSQLFIW--M 464

  Fly   408 SASVIILRYR 417
            |.|:..:|:|
Yeast   465 SMSLSHIRFR 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	86/433 (20%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
TAT1	NP_009625.1	2A0310	91..567	CDD:273334	84/425 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I2106
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1545
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870