DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and AGP1

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_009905.3	Gene:	AGP1 / 850333	SGDID:	S000000530	Length:	633	Species:	Saccharomyces cerevisiae

Alignment Length:	482	Identity:	100/482 - (20%)
Similarity:	171/482 - (35%)	Gaps:	130/482 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PSSRRAILRHILSGICTKMNRTKS-----VPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLT 61
            ||||:|          .::.:.:|     ..|......|.:.:....:.::.:|..:|.|:.|..
Yeast    88 PSSRQA----------QELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGN 142

  Fly    62 GTVAKEMAGP-GIILSFILAGFISML-------AALCYAEFGTRVPKAGSAYVYTYISMGEFWAF 118
            || |...||| |:::.:.:.|.|...       .||.|:..      .|....|....:.:.:.|
Yeast   143 GT-ALVHAGPAGLLIGYAIMGSILYCIIQACGEMALVYSNL------TGGYNAYPSFLVDDGFGF 200

  Fly   119 VIGWNILLE-------HMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAF 176
            .:.|...|:       .::.|:...:.|:..|:                          |||...
Yeast   201 AVAWVYCLQWLCVCPLELVTASMTIKYWTTSVN--------------------------PDVFVI 239

  Fly   177 ----LVCIVYAAALAGGVKATAVFN--SLLTLVNIAVMVLVISVG-----------FWYADGK-N 223
                ||..:......|..:|...||  .:|.:....::.::|.||           :|:..|. |
Yeast   240 IFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFN 304

  Fly   224 WSEAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVAT------VISLFVVT 282
            ...|...|     .||.|...|..:||.|.:.||.:..|..||..:||.|.      ::.||:.|
Yeast   305 GKHAIDRF-----KGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLAT 364

  Fly   283 VGYILVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGA--------------LCGMTT 333
            :  ||    |..::|   .|....|....|....|  .|:|::.:              |..:.:
Yeast   365 I--IL----LGFLVP---YNSDQLLGSTGGGTKAS--PYVIAVASHGVRVVPHFINAVILLSVLS 418

  Fly   334 TLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVS---GVMSACLA-----LVFDLA 390
            ....|.::..|....::..|.....|..|:...: ||:.:.||   .|::.|.|     .||  .
Yeast   419 MANSSFYSSARLFLTLSEQGYAPKVFSYIDRAGR-PLIAMGVSALFAVIAFCAASPKEEQVF--T 480

  Fly   391 KLVEFMSIGTLLAYTIVSASVIILRYR 417
            .|:....:..|..:|.:..|  .||:|
Yeast   481 WLLAISGLSQLFTWTAICLS--HLRFR 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	93/447 (21%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617
AGP1	NP_009905.3	2A0310	117..597	CDD:273334	92/443 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345717
Domainoid	1	1.000	76	1.000	Domainoid score	I2106
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1545
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	7	6.800