DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and CAT2

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_849822.1	Gene:	CAT2 / 842170	AraportID:	AT1G58030	Length:	635	Species:	Arabidopsis thaliana

Alignment Length:	637	Identity:	206/637 - (32%)
Similarity:	324/637 - (50%)	Gaps:	99/637 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFISMLAALCYAEFGTRVP 99
            |.|.|....:..:|:|..:|||:|:|.||||:|.:||.:.|||::||..:.|:|.||||..:|.|
plant    40 LARALTVPHLVAIGVGATIGAGVYILVGTVAREHSGPSLALSFLIAGIAAGLSAFCYAELSSRCP 104

  Fly   100 KAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHE 164
            .|||||.|:||.:||..|::|||.::||:.:|.::|||..|..:..:.||..|   |......|:
plant   105 SAGSAYHYSYICVGEGVAWIIGWALILEYTIGGSAVARGISPNLALIFGGEDG---LPAILARHQ 166

  Fly   165 -PGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGKNWS--E 226
             |||....|..|.::..|....|..|:|.:.....::|.||:.|::.||..|.:......|.  |
plant   167 IPGLDIVVDPCAAILVFVVTGLLCMGIKESTFAQGIVTAVNVCVLLFVIVAGSYLGFKTGWPGYE 231

  Fly   227 AEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAA 291
            ...||.|:||.|:.||:||.|:||:||||:|::.||.:||...:|:...::|.:....|::||..
plant   232 LPTGFFPFGVDGMFAGSATVFFAFIGFDSVASTAEEVRNPQRDLPIGIGLALLLCCSLYMMVSIV 296

  Fly   292 LTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLF 356
            :..:||...::|...:..||...::.||.|||::||:..:.:.|:|:|...||.:.|||.||||.
plant   297 IVGLIPYYAMDPDTPISSAFASHDMQWAVYLITLGAVMALCSALMGALLPQPRILMAMARDGLLP 361

  Fly   357 SCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRP--- 418
            |.|..||..||||:...|.:|:.:|.||...|:::|...:|:|||||:|:|:.||:||||.|
plant   362 SIFSDINKRTQVPVKATVATGLCAATLAFFMDVSQLAGMVSVGTLLAFTMVAISVLILRYVPPDE 426

  Fly   419 -------MERIHTTIRVPAVAGSPDDDDDDDEDVASQSSMDTSSPT------------------- 457
                   .|||.:   |..:.|          :..|...:.||..:
plant   427 QPLPSSLQERIDS---VSFICG----------ETTSSGHVGTSDSSHQPLIVNNDALVDVPLIKN 478

  Fly   458 ---------SEMIEEVLAGRLKAQFRCLEPLLGRFEPGSVVSVAVMLFIF---LSFAICVELKVS 510
                     ||....::|| ....|.|    :|.|    ::|.|.....|   :.:.:|
plant   479 QEALGCLVLSEETRRIVAG-WSIMFTC----VGAF----LLSYAASSLSFPGLIRYPLC------ 528

  Fly   511 WTQLYTGTWWALIIYGFIIFAAGTCVAVIAVHNQNTRGLI-----FKVPLVPFVPALGIFCNILL 570
                  |....|::.|.|        |:.::...:.|...     :..|.||.:|.:.|..|:.|
plant   529 ------GVGGCLLLAGLI--------ALSSIDQDDARHTFGHSGGYMCPFVPLLPIICILINMYL 579

  Fly   571 MVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKEGEVCSSYSILMTTSEAGKV 622
            :|:|.:.||.|..||:.||::||..||.:||.     .:.::.:||:.|.::
plant   580 LVNLGSATWARVSVWLLIGVIVYVFYGRKNSS-----LANAVYVTTAHAEEI 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	203/616 (33%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617	20/49 (41%)
CAT2	NP_849822.1	2A0303	20..610	CDD:273330	201/614 (33%)
CAT2	NP_849822.1	AA_permease_C	560..610	CDD:290617	20/49 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	307	1.000	Domainoid score	I322
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	352	1.000	Inparanoid score	I609
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm1003
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830