DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13248 and CAT8

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_173155.1	Gene:	CAT8 / 838282	AraportID:	AT1G17120	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	609	Identity:	173/609 - (28%)
Similarity:	285/609 - (46%)	Gaps:	115/609 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LSGICTKM-NRTKSVPTDV---------METPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKE 67
            ||..|.:: :|..|..:|.         .|.|:.|||..:|:..|..|.:||:|::|:||..|:.
plant    49 LSATCPRLADRLLSRSSDAYELDAARRESENPMRRCLTWWDLLWLSFGSVVGSGVFVITGQEARV 113

  Fly    68 MAGPGIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGA 132
            .|||.::||:.::|..::|:.|||||||..:|.||.::.|..:.:|:|.||:...|||||.|:||
plant   114 GAGPAVVLSYAISGVSALLSVLCYAEFGVEIPVAGGSFSYLRVELGDFIAFIAAGNILLEAMVGA 178

  Fly   133 ASVARAWSGY---------------VDSMLGGWIGNTTLELTGGIHEPGLAQYPDVLAFLVCIVY 182
            |.:.|:||.|               |||...|:                  ...|.:|..|.:|.
plant   179 AGLGRSWSSYLASLVKNDSDYFRIKVDSFAKGF------------------DLLDPVAVAVLLVA 225

  Fly   183 AAALAGGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGKNWSEAEGGFLPYGVGGVIAGAATCF 247
            ......|.|.|:..|.:.::|.:.::|.::.|||.::...|...    |.|||..||:..||..:
plant   226 NGIAMTGTKRTSWLNLITSMVTVCIIVFIVVVGFTHSKTSNLVP----FFPYGAKGVVQSAAVVY 286

  Fly   248 YAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFG 312
            :::.|||.:|...||.:.||..||:..|.|:.::||.|.|::.|||:|:..:||:..|:...||.
plant   287 WSYTGFDMVANMAEETEKPSRDIPIGLVGSMSMITVVYCLMALALTMMVKYTEIDANAAYSVAFA 351

  Fly   313 QLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVSG 377
            |:.:.|||||:.|.||.||||:||.......|....:|...::...|..::|.|..|:...::..
plant   352 QIGMKWAKYLVGICALKGMTTSLLVGSLGQARYTTQIARSHMIPPWFALVHPKTGTPIYATLLVT 416

  Fly   378 VMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAGSPDDDDDDD 442
            ::|:.::....|..|....|..||..:.:|:.::::.||..
plant   417 ILSSIISFFTSLEVLSSVFSFATLFIFMLVAVALLVRRYYV------------------------ 457

  Fly   443 EDVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGRFEPGSVVSVAVMLFIFLSFAICVEL 507
            :||..:                 ||.||        .||              |:||..|..:.:
plant   458 KDVTPE-----------------AGLLK--------FLG--------------FLFLIIASSIGV 483

  Fly   508 KVSWTQLYTGTWWALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALGIFCNILLMV 572
            ...|.....| |.|..:.|.|.|.....:|::..:....   ::.|||||::|:..|..|:.|:.
plant   484 SALWNSGVKG-WIAYTVTGVIWFIGTLGLALLPKYRVPK---VWGVPLVPWLPSFSIAMNLFLIG 544

  Fly   573 HLDAVTWVRFFVWVCIGMVVYFLY 596
            .|..|.::||.:...: |::|:|:
plant   545 SLGYVAFLRFIICTMV-MLLYYLF 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	167/580 (29%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617	16/46 (35%)
CAT8	NP_173155.1	2A0303	77..575	CDD:273330	167/581 (29%)
CAT8	NP_173155.1	AA_permease_C	523..573	CDD:290617	16/46 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870