DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13248 and CAT3

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_198510.2	Gene:	CAT3 / 833664	AraportID:	AT5G36940	Length:	609	Species:	Arabidopsis thaliana

Alignment Length:	611	Identity:	196/611 - (32%)
Similarity:	309/611 - (50%)	Gaps:	99/611 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFISMLAALCYAEFGTRVP 99
            |.:.|....:..:|:|..:|||:|:|.||||:|.:||.:.|||::||..:.|:|.||||..:|.|
plant    29 LAKALTFPHLIAIGVGSTIGAGVYILVGTVAREHSGPALALSFLIAGISAALSAFCYAELSSRFP 93

  Fly   100 KAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGGWIGNTTLELTGGIHE 164
            .|||||.|:||.:||..|::|||.::||:.:|.::|||..|..:..:.|   |...|......|:
plant    94 SAGSAYHYSYICIGEGVAWLIGWALILEYTIGGSTVARGISPNLAMIFG---GEDCLPTILARHQ 155

  Fly   165 -PGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGKNW--SE 226
             |||....|..|.::..:.......|||.:.....::|..|:.||:.||..|.:......|  .|
plant   156 IPGLDIVVDPCAAVLVFIVTGLCCLGVKESTFAQGIVTTANVFVMIFVIVAGSYLCFKTGWVGYE 220

  Fly   227 AEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAA 291
            ...|:.||||.|::.|:||.|:|::|||::|:..||.|||...:|:...|||.:..:.|::||..
plant   221 LPTGYFPYGVDGMLTGSATVFFAYIGFDTVASMAEEVKNPRRDLPLGIGISLLLCCLLYMMVSVV 285

  Fly   292 LTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLF 356
            :..::|...::|...:..||....:.||.|||::||:..:.:.|:||:...||.:.|||.||||.
plant   286 IVGLVPYYAMDPDTPISSAFSSHGIQWAAYLINLGAVMALCSALMGSILPQPRILMAMARDGLLP 350

  Fly   357 SCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMER 421
            |.|..:|..||||:...:.:||.:|.||...|:::|...:|:|||:|:|:|:.|::|:||
plant   351 SYFSYVNQRTQVPINGTITTGVCAAILAFFMDVSQLAGMVSVGTLVAFTMVAISLLIVRY----- 410

  Fly   422 IHTTIRVPAVAGSPDDDDDDDEDVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGRFE-- 484
                 .||     ||:                 .|....::|..:..:....|..:||||:.:
plant   411 -----VVP-----PDE-----------------VPLPSSLQENSSSHVGTSIRSKQPLLGKVDDS 448

  Fly   485 -------PGS------------------------VVSVAVMLFI---FLSFAICVELKVSWTQLY 515
                   |||                        ::|.|...|:   .|.:::|
plant   449 VVDKENAPGSWVLNKKNRRKFAGWSIMFTCIGNFLLSYAASSFLLPGLLRYSLC----------- 502

  Fly   516 TGTWWALIIYGFIIFAAGTCVAVIAVHNQNTRGLI-----FKVPLVPFVPALGIFCNILLMVHLD 575
             |.....::.|.|:        :|.:...:.|...     |..|.||.:|.:.|..|:.|:|:|.
plant   503 -GVGGLFLLVGLIV--------LICIDQDDARHSFGHSGGFICPFVPLLPIVCILINMYLLVNLG 558

  Fly   576 AVTWVRFFVWVCIGMVVYFLYGIRNS 601
            |.||||..||:.:|:|||..||.|||
plant   559 AATWVRVSVWLFLGVVVYIFYGRRNS 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	196/611 (32%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617	24/49 (49%)
CAT3	NP_198510.2	2A0303	5..584	CDD:273330	194/609 (32%)
CAT3	NP_198510.2	AA_permease_C	534..584	CDD:290617	24/49 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	307	1.000	Domainoid score	I322
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	352	1.000	Inparanoid score	I609
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm1003
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830