DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13248 and CAT4

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001154586.1	Gene:	CAT4 / 821176	AraportID:	AT3G03720	Length:	600	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	188/577 - (32%)
Similarity:	321/577 - (55%)	Gaps:	32/577 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILSFILAGFISMLAALCYAEFGTRVP 99
            |.:.|:..|:..:|:|..:|||:|:|.||||:|..||.:.:||.:||..:.|:|.||||..:|.|
plant    24 LAKKLSAVDLVAIGVGTTIGAGVYILVGTVAREHTGPALAVSFFIAGVAAALSACCYAELASRCP 88

  Fly   100 KAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSGYVDSMLGG------WIGNTTLEL 158
            .|||||.|.||.:||..|:::||.::|::.:|.:::||..:..:.|..||      ::...|:
plant    89 SAGSAYHYAYICLGEGIAWLVGWALVLDYTIGGSAIARGITPNLASFFGGLDNLPVFLARQTI-- 151

  Fly   159 TGGIHEPGLAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGKN 223
                  ||:....|..|.|:.::....|..|:|.::...:::|.||:..:|.:|.||.:.|....
plant   152 ------PGVGIVVDPCAALLIMIVTILLCFGIKESSTVQAIVTSVNVCTLVFIIVVGGYLACKTG 210

  Fly   224 W--SEAEGGFLPYGVGGVIAGAATCFYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYI 286
            |  .:...|:.|:|:.|::||:|..|::::|||::.::.||.|||...:|:...|:|.:..:.|:
plant   211 WVGYDLPSGYFPFGLNGILAGSAVVFFSYIGFDTVTSTAEEVKNPQRDLPLGIGIALLICCILYM 275

  Fly   287 LVSAALTLMIPISEINPAASLPEAFGQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMAS 351
            |:|..:..::|...:||...:..|||...:.||.|:::.||:..:..:|||||.|.||...|||.
plant   276 LLSVVIVGLVPYYSLNPDTPISSAFGDSGMQWAAYILTTGAITALCASLLGSLLAQPRIFMAMAR 340

  Fly   352 DGLLFSCFGKINPTTQVPLLNLVVSGVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRY 416
            ||||.:.|.:|:|.||||:.:.:..||::|.||...|:|:|.|.:|:|||:|:|.|:..|::|||
plant   341 DGLLPAFFSEISPRTQVPVKSTIAIGVLAAALAFFMDVAQLSEMVSVGTLMAFTAVAVCVLVLRY 405

  Fly   417 RPMERIHTTIRVPAVAGSPDDDDDDDEDVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLG 481
            .|.:      .||..:.|....|.|:....:::.:..:..:|   :..|.|...|:.   |...|
plant   406 VPPD------GVPLSSSSQTLSDTDESRAETENFLVDAIESS---DSPLLGNETARD---EKYFG 458

  Fly   482 RFEPGSVVSVAVMLF--IFLSFAICVELKVSWTQLYTGTWWALIIYGFIIFAAGTCVAVIAVHNQ 544
            :....:..|:|::..  :.|:.|...|...|:.:.......|:|:.|.:| ..|........||.
plant   459 KRRKIAAWSIALVCIGVLGLASAASAERLPSFPRFTICGVSAVILLGSLI-TLGYIDEDEERHNF 522

  Fly   545 NTRGLIFKVPLVPFVPALGIFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNS 601
            ..:| .|..|.||::|.|.|..|..|::::.|.||:|..:|:.||.::|..||..:|
plant   523 GHKG-GFLCPFVPYLPVLCILINTYLIINIGAGTWIRVLIWLLIGSMIYIFYGRSHS 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	188/577 (33%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617	19/49 (39%)
CAT4	NP_001154586.1	2A0303	4..579	CDD:273330	188/577 (33%)
CAT4	NP_001154586.1	AA_permease_C	528..578	CDD:290617	19/49 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	307	1.000	Domainoid score	I322
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	352	1.000	Inparanoid score	I609
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm1003
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830