DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13248 and CAT7

DIOPT Version :9

Sequence 1:	NP_649219.1	Gene:	CG13248 / 40254	FlyBaseID:	FBgn0036984	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_187671.1	Gene:	CAT7 / 820229	AraportID:	AT3G10600	Length:	584	Species:	Arabidopsis thaliana

Alignment Length:	633	Identity:	180/633 - (28%)
Similarity:	299/633 - (47%)	Gaps:	126/633 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PS--SRRAILRHILSGICTKMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTV 64
            ||  ||||:   .:|....:|:|.::|..:.|    .|.|..:|:..||||.|:|||::|.||..
plant    28 PSRFSRRAV---SVSTSYDEMSRVRAVSGEQM----RRTLRWYDLIGLGIGGMIGAGVFVTTGRA 85

  Fly    65 AKEMAGPGIILSFILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHM 129
            ::..|||.|::|:.:||..::|:|.||.||...:|.||.|:.|..|:.|||.||:.|.|::::::
plant    86 SRLYAGPSIVVSYAIAGLCALLSAFCYTEFAVHLPVAGGAFSYIRITFGEFPAFITGANLIMDYV 150

  Fly   130 LGAASVARAWSGYVDSMLGGWIGNTTLE-------LTGGIHEPGLAQYPDVLAFLVCIVYAAALA 187
            |..|:|:|.::.|    ||...|.:|.|       |..|.:|      .|.:|.:|.:.....:.
plant   151 LSNAAVSRGFTAY----LGSAFGISTSEWRFIVSGLPNGFNE------IDPIAVIVVLAVTFVIC 205

  Fly   188 GGVKATAVFNSLLTLVNIAVMVLVISVGFWYADGKNWS-----EAEGGFLPYGVGGVIAGAATCF 247
            ...:.::..|.:||.::||.:|.||.:||...|.||.:     |...||.|:||.||..|||..:
plant   206 YSTRESSKVNMVLTALHIAFIVFVIVMGFSKGDVKNLTRPDNPENPSGFFPFGVSGVFNGAAMVY 270

  Fly   248 YAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAFG 312
            .:::|:|:::|..||.|:|...||:....|:.:|.|.|.|::.::::::|...|:..|....||.
plant   271 LSYIGYDAVSTMAEEVKDPVKDIPMGISGSVAIVIVLYCLMAISMSMLLPYDLIDAEAPYSAAFS 335

  Fly   313 QL-NLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVS 376
            :. ...|...::.|||..|:.|:|:.::....|.|..:....::...|.|::|.|..|:......
plant   336 KSEGWEWVTRVVGIGASFGILTSLIVAMLGQARYMCVIGRSRVVPIWFAKVHPKTSTPVNASAFL 400

  Fly   377 GVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAGSPDDDDDD 441
            |:.:|.|||..||..|:..:|||||..:.:|:.:||..||       .|:
plant   401 GIFTAVLALFTDLNVLLNLVSIGTLFVFYMVANAVIFRRY-------VTV--------------- 443

  Fly   442 DEDVASQSSMDTSSPTSEMIEEVLAGRLKAQFRCLEPLLGRFEPGSVVSVAVMLFIFLSFAICVE 506
                                                   |..||...:|. :.||...|.
plant   444 ---------------------------------------GYTEPWPTLSF-LCLFSITSI----- 463

  Fly   507 LKVSWTQLYTGTW---------WALIIYGFIIFAAG-TCVAVIAVHN----QNTRGLIFKVPLVP 557
                   |:|..|         |      ||:.|:. |.:|::.:.:    |......:.|||:|
plant   464 -------LFTLVWQLAPSGPPKW------FILGASTVTAIAIVQIFHCVVPQARIPEFWGVPLMP 515

  Fly   558 FVPALGIFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKEGE 605
            :.|.:.||.||.|:..|||.:::||..:..:.::||..|.:..|.:.|
plant   516 WTPCVSIFLNIFLLGSLDAPSYIRFGFFSGLVVLVYVFYSVHASYDAE 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	168/597 (28%)
CG13248	NP_649219.1	AA_permease_C	551..601	CDD:290617	18/49 (37%)
CAT7	NP_187671.1	2A0303	50..561	CDD:273330	170/604 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870